Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania
Problem. Factors related to MDRTB mortality in Tanzania have not been adequately explored and reported. Objectives. To determine demographic, clinical, radiographic, and laboratory factors associated with MDRTB mortality in a Tanzanian TB Referral Hospital. Methodology. This was a cross-sectional st...
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ftdoajarticles:oai:doaj.org/article:b1be9f341e1b44f4941b680665d172e3 2023-05-15T15:06:19+02:00 Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania Edson W. Mollel Jaffu O. Chilongola 2017-01-01T00:00:00Z https://doi.org/10.1155/2017/9241238 https://doaj.org/article/b1be9f341e1b44f4941b680665d172e3 EN eng Hindawi Limited http://dx.doi.org/10.1155/2017/9241238 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2017/9241238 https://doaj.org/article/b1be9f341e1b44f4941b680665d172e3 Journal of Tropical Medicine, Vol 2017 (2017) Arctic medicine. Tropical medicine RC955-962 article 2017 ftdoajarticles https://doi.org/10.1155/2017/9241238 2022-12-31T02:08:20Z Problem. Factors related to MDRTB mortality in Tanzania have not been adequately explored and reported. Objectives. To determine demographic, clinical, radiographic, and laboratory factors associated with MDRTB mortality in a Tanzanian TB Referral Hospital. Methodology. This was a cross-sectional study with 193 participants. Demographic, clinical, laboratory, and radiological data were collected, and their associations with mortality among MDRTB patients were determined. Results and Conclusions. Cough was the commonest finding among these MDRTB patients, with 179 (92.75%) of them presenting with cough, followed by chest X-ray consolidation in 156 patients (80.83%) and history of previous TB treatment in 151 patients (78.24%). Cigarette smoking, HIV positivity, and low CD4 counts were significantly associated with MDRTB mortality, p values of 0.034, 0.044, and 0.048, respectively. Fever on the other hand was at the borderline with p value of 0.059. We conclude that cigarette smoking and HIV status are significant risk factors for mortality among MDRTB patients. HIV screening should continually be emphasized among patients and the general community for early ARTs initiation. Based on the results from our study, policy makers and public health personnel should consider addressing tobacco cessation as part of national TB control strategy. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Tropical Medicine 2017 1 6 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 |
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Arctic medicine. Tropical medicine RC955-962 Edson W. Mollel Jaffu O. Chilongola Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Problem. Factors related to MDRTB mortality in Tanzania have not been adequately explored and reported. Objectives. To determine demographic, clinical, radiographic, and laboratory factors associated with MDRTB mortality in a Tanzanian TB Referral Hospital. Methodology. This was a cross-sectional study with 193 participants. Demographic, clinical, laboratory, and radiological data were collected, and their associations with mortality among MDRTB patients were determined. Results and Conclusions. Cough was the commonest finding among these MDRTB patients, with 179 (92.75%) of them presenting with cough, followed by chest X-ray consolidation in 156 patients (80.83%) and history of previous TB treatment in 151 patients (78.24%). Cigarette smoking, HIV positivity, and low CD4 counts were significantly associated with MDRTB mortality, p values of 0.034, 0.044, and 0.048, respectively. Fever on the other hand was at the borderline with p value of 0.059. We conclude that cigarette smoking and HIV status are significant risk factors for mortality among MDRTB patients. HIV screening should continually be emphasized among patients and the general community for early ARTs initiation. Based on the results from our study, policy makers and public health personnel should consider addressing tobacco cessation as part of national TB control strategy. |
format |
Article in Journal/Newspaper |
author |
Edson W. Mollel Jaffu O. Chilongola |
author_facet |
Edson W. Mollel Jaffu O. Chilongola |
author_sort |
Edson W. Mollel |
title |
Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania |
title_short |
Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania |
title_full |
Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania |
title_fullStr |
Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania |
title_full_unstemmed |
Predictors for Mortality among Multidrug-Resistant Tuberculosis Patients in Tanzania |
title_sort |
predictors for mortality among multidrug-resistant tuberculosis patients in tanzania |
publisher |
Hindawi Limited |
publishDate |
2017 |
url |
https://doi.org/10.1155/2017/9241238 https://doaj.org/article/b1be9f341e1b44f4941b680665d172e3 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Tropical Medicine, Vol 2017 (2017) |
op_relation |
http://dx.doi.org/10.1155/2017/9241238 https://doaj.org/toc/1687-9686 https://doaj.org/toc/1687-9694 1687-9686 1687-9694 doi:10.1155/2017/9241238 https://doaj.org/article/b1be9f341e1b44f4941b680665d172e3 |
op_doi |
https://doi.org/10.1155/2017/9241238 |
container_title |
Journal of Tropical Medicine |
container_volume |
2017 |
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1 |
op_container_end_page |
6 |
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1766337945984303104 |