Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal ( Phoca vitulina ) population
Abstract Background Brucella is a group of bacteria that causes brucellosis, which can affect population health and reproductive success in many marine mammals. We investigated the serological prevalence of antibodies against Brucella bacteria in a declining harbor seal population in Glacier Bay Nat...
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ftdoajarticles:oai:doaj.org/article:b1a42be375294172a51aec3135886707 2023-05-15T16:20:26+02:00 Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal ( Phoca vitulina ) population Hueffer Karsten Gende Scott M O’Hara Todd M 2013-01-01T00:00:00Z https://doi.org/10.1186/1751-0147-55-2 https://doaj.org/article/b1a42be375294172a51aec3135886707 EN eng BMC http://www.actavetscand.com/content/55/1/2 https://doaj.org/toc/1751-0147 doi:10.1186/1751-0147-55-2 1751-0147 https://doaj.org/article/b1a42be375294172a51aec3135886707 Acta Veterinaria Scandinavica, Vol 55, Iss 1, p 2 (2013) Brucella Harbor seals Alaska Assay dependence Veterinary medicine SF600-1100 article 2013 ftdoajarticles https://doi.org/10.1186/1751-0147-55-2 2022-12-31T08:46:22Z Abstract Background Brucella is a group of bacteria that causes brucellosis, which can affect population health and reproductive success in many marine mammals. We investigated the serological prevalence of antibodies against Brucella bacteria in a declining harbor seal population in Glacier Bay National Park, Alaska. Results Prevalence ranged from 16 to 74 percent for those tests detecting antibodies, indicating that harbor seals in Glacier Bay have been exposed to Brucella bacteria. However, the actual level of serological prevalence could not be determined because results were strongly assay-dependent. Conclusions This study reinforces the need to carefully consider assay choice when comparing different studies on the prevalence of anti– Brucella antibodies in pinnipeds and further highlights the need for species- or taxon-specific assay validation for both pathogen and host species. Article in Journal/Newspaper glacier harbor seal Phoca vitulina Alaska Directory of Open Access Journals: DOAJ Articles Glacier Bay Acta Veterinaria Scandinavica 55 1 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Brucella Harbor seals Alaska Assay dependence Veterinary medicine SF600-1100 |
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Brucella Harbor seals Alaska Assay dependence Veterinary medicine SF600-1100 Hueffer Karsten Gende Scott M O’Hara Todd M Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal ( Phoca vitulina ) population |
topic_facet |
Brucella Harbor seals Alaska Assay dependence Veterinary medicine SF600-1100 |
description |
Abstract Background Brucella is a group of bacteria that causes brucellosis, which can affect population health and reproductive success in many marine mammals. We investigated the serological prevalence of antibodies against Brucella bacteria in a declining harbor seal population in Glacier Bay National Park, Alaska. Results Prevalence ranged from 16 to 74 percent for those tests detecting antibodies, indicating that harbor seals in Glacier Bay have been exposed to Brucella bacteria. However, the actual level of serological prevalence could not be determined because results were strongly assay-dependent. Conclusions This study reinforces the need to carefully consider assay choice when comparing different studies on the prevalence of anti– Brucella antibodies in pinnipeds and further highlights the need for species- or taxon-specific assay validation for both pathogen and host species. |
format |
Article in Journal/Newspaper |
author |
Hueffer Karsten Gende Scott M O’Hara Todd M |
author_facet |
Hueffer Karsten Gende Scott M O’Hara Todd M |
author_sort |
Hueffer Karsten |
title |
Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal ( Phoca vitulina ) population |
title_short |
Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal ( Phoca vitulina ) population |
title_full |
Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal ( Phoca vitulina ) population |
title_fullStr |
Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal ( Phoca vitulina ) population |
title_full_unstemmed |
Assay dependence of Brucella antibody prevalence in a declining Alaskan harbor seal ( Phoca vitulina ) population |
title_sort |
assay dependence of brucella antibody prevalence in a declining alaskan harbor seal ( phoca vitulina ) population |
publisher |
BMC |
publishDate |
2013 |
url |
https://doi.org/10.1186/1751-0147-55-2 https://doaj.org/article/b1a42be375294172a51aec3135886707 |
geographic |
Glacier Bay |
geographic_facet |
Glacier Bay |
genre |
glacier harbor seal Phoca vitulina Alaska |
genre_facet |
glacier harbor seal Phoca vitulina Alaska |
op_source |
Acta Veterinaria Scandinavica, Vol 55, Iss 1, p 2 (2013) |
op_relation |
http://www.actavetscand.com/content/55/1/2 https://doaj.org/toc/1751-0147 doi:10.1186/1751-0147-55-2 1751-0147 https://doaj.org/article/b1a42be375294172a51aec3135886707 |
op_doi |
https://doi.org/10.1186/1751-0147-55-2 |
container_title |
Acta Veterinaria Scandinavica |
container_volume |
55 |
container_issue |
1 |
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1766008356159356928 |