Radiometric detection of metabolic activity of Paracoccidioides brasiliensis and its susceptibility to amphotericin B and diethylstilbestrol

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Edwaldo E. Camargo, Maria K. Sato, Gilda M. B. Del Negro, Carlos da Silva Lacaz
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP) 1987
• Subjects: Paracoccidioides brasiliensis; Radiometric assay; 14C-Substrates; Amphotericin B; Diethylstilbestrol; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; The ''Y''
• Online Access: https://doi.org/10.1590/S0036-46651987000500005; https://doaj.org/article/b104e73659b04bf7b585355a7ac3d306

Paracoccidioidomycosis (South American blastomycosis) is a systemic disease, strikingly more frequent in males, caused by the dimorphic fungus Paracoccidioides brasiliensis. A radiometric assay system has been applied to study the metabolic activity and the effect of drugs on this fungus "in vi...