A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka
Abstract Background Melioidosis is an infection caused by a facultative intracellular Gram-negative bacterium, Burkholderia pseudomallei. It can present as septicemia, localized infection with/without septicemia, asymptomatic infections, ulcers, pneumonia, visceral abscesses, neurological infection,...
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ftdoajarticles:oai:doaj.org/article:b0791283c5034e8e8819984b1b7d155b 2023-05-15T15:14:59+02:00 A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka A. K. T. M. Karunarathna S. A. Mendis W. P. D. P. Perera Geethika Patabendige A. S. Pallewatte Aruna Kulatunga 2018-09-01T00:00:00Z https://doi.org/10.1186/s40794-018-0073-5 https://doaj.org/article/b0791283c5034e8e8819984b1b7d155b EN eng BMC http://link.springer.com/article/10.1186/s40794-018-0073-5 https://doaj.org/toc/2055-0936 doi:10.1186/s40794-018-0073-5 2055-0936 https://doaj.org/article/b0791283c5034e8e8819984b1b7d155b Tropical Diseases, Travel Medicine and Vaccines, Vol 4, Iss 1, Pp 1-6 (2018) Melioidosis Burkholderia pseudomallei Musculoskeletal manifestations of melioidosis Multiple intramuscular abscesses Sacroiliitis Intensive phase Arctic medicine. Tropical medicine RC955-962 article 2018 ftdoajarticles https://doi.org/10.1186/s40794-018-0073-5 2022-12-31T14:46:47Z Abstract Background Melioidosis is an infection caused by a facultative intracellular Gram-negative bacterium, Burkholderia pseudomallei. It can present as septicemia, localized infection with/without septicemia, asymptomatic infections, ulcers, pneumonia, visceral abscesses, neurological infection, musculoskeletal infections and can involve any organ. Case presentation A 56 year old Sri Lankan diabetic female presented with fever, chills and rigors for 2 weeks. She also had malaise and loss of appetite, but no other features. On examination, she was febrile (temperature was 101.4 0 F) and rest of the examination was unremarkable. Her blood culture was positive for Burkholderia pseudomallei and she was started on IV antibiotics, on day 3. During her 2nd week of hospital stay, she developed right sided low back pain with buttock pain, right hip joint pain and restricted hip joint movements suggestive of right sacroiliitis. CE CT and MRI scans confirmed the diagnosis of right iliopsoas abscesses and right sacroiliitis. Incision and drainage was performed and a pigtail catheter was left in place for continuous drainage of abscesses. Her intensive phase was initiated with IV ceftazidime 2 g every 6 h for 12 days, then changed over to IV meropenem 2 g every 8 h together with oral co-trimoxazole. 2 weeks later, oral co-trimoxazole was replaced by oral doxycycline for another 6 weeks (due to transient pancytopaenia). She made a complete and uneventful recovery with oral co-trimoxazole for another 6 months, in her eradication phase. We report this case to show the importance in early diagnosis of melioidosis, and to consider it in the differential diagnosis of multiple abscesses and to emphasize the importance in suspecting melioidosis as a causative agent in infective sacroiliitis. Discussion Melioidosis can have 2 major presentations; acute infection (symptoms lasting less than 2 months) and chronic infection (symptoms lasting more than 2 months). Musculoskeletal melioidosis is a well-recognized manifestation of the ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Diseases, Travel Medicine and Vaccines 4 1 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Melioidosis Burkholderia pseudomallei Musculoskeletal manifestations of melioidosis Multiple intramuscular abscesses Sacroiliitis Intensive phase Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Melioidosis Burkholderia pseudomallei Musculoskeletal manifestations of melioidosis Multiple intramuscular abscesses Sacroiliitis Intensive phase Arctic medicine. Tropical medicine RC955-962 A. K. T. M. Karunarathna S. A. Mendis W. P. D. P. Perera Geethika Patabendige A. S. Pallewatte Aruna Kulatunga A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka |
topic_facet |
Melioidosis Burkholderia pseudomallei Musculoskeletal manifestations of melioidosis Multiple intramuscular abscesses Sacroiliitis Intensive phase Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Melioidosis is an infection caused by a facultative intracellular Gram-negative bacterium, Burkholderia pseudomallei. It can present as septicemia, localized infection with/without septicemia, asymptomatic infections, ulcers, pneumonia, visceral abscesses, neurological infection, musculoskeletal infections and can involve any organ. Case presentation A 56 year old Sri Lankan diabetic female presented with fever, chills and rigors for 2 weeks. She also had malaise and loss of appetite, but no other features. On examination, she was febrile (temperature was 101.4 0 F) and rest of the examination was unremarkable. Her blood culture was positive for Burkholderia pseudomallei and she was started on IV antibiotics, on day 3. During her 2nd week of hospital stay, she developed right sided low back pain with buttock pain, right hip joint pain and restricted hip joint movements suggestive of right sacroiliitis. CE CT and MRI scans confirmed the diagnosis of right iliopsoas abscesses and right sacroiliitis. Incision and drainage was performed and a pigtail catheter was left in place for continuous drainage of abscesses. Her intensive phase was initiated with IV ceftazidime 2 g every 6 h for 12 days, then changed over to IV meropenem 2 g every 8 h together with oral co-trimoxazole. 2 weeks later, oral co-trimoxazole was replaced by oral doxycycline for another 6 weeks (due to transient pancytopaenia). She made a complete and uneventful recovery with oral co-trimoxazole for another 6 months, in her eradication phase. We report this case to show the importance in early diagnosis of melioidosis, and to consider it in the differential diagnosis of multiple abscesses and to emphasize the importance in suspecting melioidosis as a causative agent in infective sacroiliitis. Discussion Melioidosis can have 2 major presentations; acute infection (symptoms lasting less than 2 months) and chronic infection (symptoms lasting more than 2 months). Musculoskeletal melioidosis is a well-recognized manifestation of the ... |
format |
Article in Journal/Newspaper |
author |
A. K. T. M. Karunarathna S. A. Mendis W. P. D. P. Perera Geethika Patabendige A. S. Pallewatte Aruna Kulatunga |
author_facet |
A. K. T. M. Karunarathna S. A. Mendis W. P. D. P. Perera Geethika Patabendige A. S. Pallewatte Aruna Kulatunga |
author_sort |
A. K. T. M. Karunarathna |
title |
A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka |
title_short |
A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka |
title_full |
A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka |
title_fullStr |
A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka |
title_full_unstemmed |
A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka |
title_sort |
case report of melioidosis complicated by infective sacroiliitis in sri lanka |
publisher |
BMC |
publishDate |
2018 |
url |
https://doi.org/10.1186/s40794-018-0073-5 https://doaj.org/article/b0791283c5034e8e8819984b1b7d155b |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Diseases, Travel Medicine and Vaccines, Vol 4, Iss 1, Pp 1-6 (2018) |
op_relation |
http://link.springer.com/article/10.1186/s40794-018-0073-5 https://doaj.org/toc/2055-0936 doi:10.1186/s40794-018-0073-5 2055-0936 https://doaj.org/article/b0791283c5034e8e8819984b1b7d155b |
op_doi |
https://doi.org/10.1186/s40794-018-0073-5 |
container_title |
Tropical Diseases, Travel Medicine and Vaccines |
container_volume |
4 |
container_issue |
1 |
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1766345372396945408 |