An update on the detection and treatment of Rickettsia felis
Laya Hun, Adriana TroyoCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa RicaAbstract: Rickettsia felis was described as a human pathogen almost two decades ago, and human infection is currently reported in 18 countries in all c...
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ftdoajarticles:oai:doaj.org/article:b059ac2f55244364a307626f83c4f211 2023-05-15T15:09:05+02:00 An update on the detection and treatment of Rickettsia felis Hun L Troyo A 2012-06-01T00:00:00Z https://doaj.org/article/b059ac2f55244364a307626f83c4f211 EN eng Dove Medical Press http://www.dovepress.com/an-update-on-the-detection-and-treatment-of-rickettsia-felis-a10201 https://doaj.org/toc/1179-7282 1179-7282 https://doaj.org/article/b059ac2f55244364a307626f83c4f211 Research and Reports in Tropical Medicine, Vol 2012, Iss default, Pp 47-55 (2012) Arctic medicine. Tropical medicine RC955-962 article 2012 ftdoajarticles 2022-12-31T02:27:03Z Laya Hun, Adriana TroyoCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa RicaAbstract: Rickettsia felis was described as a human pathogen almost two decades ago, and human infection is currently reported in 18 countries in all continents. The distribution of this species is worldwide, determined by the presence of the main arthropod vector, Ctenocephalides felis (Bouché). The list of symptoms, which includes fever, headache, myalgia, and rash, keeps increasing as new cases with unexpected symptoms are described. Moreover, the clinical presentation of R. felis infection can be easily confused with many tropical and nontropical diseases, as well as other rickettsial infections. Although specific laboratory diagnosis and treatment for this flea-borne rickettsiosis are detailed in the scientific literature, it is possible that most human cases are not being diagnosed properly. Furthermore, since the cat flea infests different common domestic animals, contact with humans may be more frequent than reported. In this review, we provide an update on methods for specific detection of human infection by R. felis described in the literature, as well as the treatment prescribed to the patients. Considering advances in molecular detection tools, as well as options for as-yet-unreported isolation of R. felis from patients in cell culture, increased diagnosis and characterization of this emerging pathogen is warranted.Keywords: Rickettsia felis, human cases, laboratory diagnosis, treatment Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Adriana ENVELOPE(-62.783,-62.783,-64.667,-64.667) Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 |
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Arctic medicine. Tropical medicine RC955-962 Hun L Troyo A An update on the detection and treatment of Rickettsia felis |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
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Laya Hun, Adriana TroyoCentro de Investigación en Enfermedades Tropicales, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa RicaAbstract: Rickettsia felis was described as a human pathogen almost two decades ago, and human infection is currently reported in 18 countries in all continents. The distribution of this species is worldwide, determined by the presence of the main arthropod vector, Ctenocephalides felis (Bouché). The list of symptoms, which includes fever, headache, myalgia, and rash, keeps increasing as new cases with unexpected symptoms are described. Moreover, the clinical presentation of R. felis infection can be easily confused with many tropical and nontropical diseases, as well as other rickettsial infections. Although specific laboratory diagnosis and treatment for this flea-borne rickettsiosis are detailed in the scientific literature, it is possible that most human cases are not being diagnosed properly. Furthermore, since the cat flea infests different common domestic animals, contact with humans may be more frequent than reported. In this review, we provide an update on methods for specific detection of human infection by R. felis described in the literature, as well as the treatment prescribed to the patients. Considering advances in molecular detection tools, as well as options for as-yet-unreported isolation of R. felis from patients in cell culture, increased diagnosis and characterization of this emerging pathogen is warranted.Keywords: Rickettsia felis, human cases, laboratory diagnosis, treatment |
format |
Article in Journal/Newspaper |
author |
Hun L Troyo A |
author_facet |
Hun L Troyo A |
author_sort |
Hun L |
title |
An update on the detection and treatment of Rickettsia felis |
title_short |
An update on the detection and treatment of Rickettsia felis |
title_full |
An update on the detection and treatment of Rickettsia felis |
title_fullStr |
An update on the detection and treatment of Rickettsia felis |
title_full_unstemmed |
An update on the detection and treatment of Rickettsia felis |
title_sort |
update on the detection and treatment of rickettsia felis |
publisher |
Dove Medical Press |
publishDate |
2012 |
url |
https://doaj.org/article/b059ac2f55244364a307626f83c4f211 |
long_lat |
ENVELOPE(-62.783,-62.783,-64.667,-64.667) |
geographic |
Adriana Arctic |
geographic_facet |
Adriana Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Research and Reports in Tropical Medicine, Vol 2012, Iss default, Pp 47-55 (2012) |
op_relation |
http://www.dovepress.com/an-update-on-the-detection-and-treatment-of-rickettsia-felis-a10201 https://doaj.org/toc/1179-7282 1179-7282 https://doaj.org/article/b059ac2f55244364a307626f83c4f211 |
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1766340312780767232 |