Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression Características clínicas e radiológicas da tuberculose pulmonar associada ao HIV de acordo com o nível de imunossupressão
Medical charts and radiographs from 38 HIV-infected patients with positive cultures for Mycobacterium tuberculosis from sputum or bronchoalveolar lavage were reviewed in order to compare the clinical, radiographic, and sputum bacilloscopy characteristics of HIV-infected patients with pulmonary tuber...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2007
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ftdoajarticles:oai:doaj.org/article:af4da465699d4e5faf466461577a1850 2023-05-15T15:18:20+02:00 Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression Características clínicas e radiológicas da tuberculose pulmonar associada ao HIV de acordo com o nível de imunossupressão Guilherme Freire Garcia Alexandre Sampaio Moura Cid Sérgio Ferreira Manoel Otávio da Costa Rocha 2007-12-01T00:00:00Z https://doi.org/10.1590/S0037-86822007000600004 https://doaj.org/article/af4da465699d4e5faf466461577a1850 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822007000600004 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822007000600004 0037-8682 1678-9849 https://doaj.org/article/af4da465699d4e5faf466461577a1850 Revista da Sociedade Brasileira de Medicina Tropical, Vol 40, Iss 6, Pp 622-626 (2007) Tuberculose pulmonar Síndrome da imunodeficiência adquirida Radiografia torácica Contagem de linfócito CD4 Pulmonary tuberculosis Acquired immunodeficiency syndrome Thoracic radiography CD4 lymphocyte count Arctic medicine. Tropical medicine RC955-962 article 2007 ftdoajarticles https://doi.org/10.1590/S0037-86822007000600004 2022-12-30T23:08:14Z Medical charts and radiographs from 38 HIV-infected patients with positive cultures for Mycobacterium tuberculosis from sputum or bronchoalveolar lavage were reviewed in order to compare the clinical, radiographic, and sputum bacilloscopy characteristics of HIV-infected patients with pulmonary tuberculosis according to CD4+ lymphocyte count (CD4). The mean age of the patients was 32 years and 76% were male. The median CD4 was 106 cells/mm³ and 71% had CD4 < 200 cells/mm³. Sputum bacilloscopy was positive in 45% of the patients. Patients with CD4 < 200 cells/mm³ showed significantly less post-primary pattern (7% vs. 63%; p = 0.02) and more frequently reported weight loss (p = 0.04). Although not statistically significant, patients with lower CD4 showed lower positivity of sputum bacilloscopy (37% vs. 64%; p = 0.18). HIV-infected patients with culture-confirmed pulmonary tuberculosis had a high proportion of non-post-primary pattern in thoracic radiographs. Patients with CD4 lower than 200 cells/mm³ showed post-primary patterns less frequently and reported weight loss more frequently. Foram revisados prontuários e radiografias de 38 pacientes infectados pelo HIV com culturas de escarro ou lavado broncoalveolar positivas para Mycobacterium tuberculosis no intuito de comparar características clínicas, radiológicas e baciloscópicas de pacientes HIV-positivos com tuberculose pulmonar de acordo com a contagem de linfócitos CD4. A idade média dos pacientes foi 32 anos e 76% eram homens. Mediana de CD4 foi 106 cells/mm³ e 71% tinham CD4 <200cel/mm³. Baciloscopia de escarro foi positiva em 45%. Pacientes com CD4 <200 cel/mm³ apresentaram significativamente menos padrão pós-primário (p=0,02) e relataram emagrecimento mais freqüentemente (p=0,04). Embora sem significância estatística, pacientes com contagem mais baixa de CD4 apresentaram menor positividade na baciloscopia de escarro (p=0,18). Pacientes HIV-positivos com tuberculose pulmonar confirmada por cultura apresentam alta proporção de padrão diferentes do ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Alta Arctic Revista da Sociedade Brasileira de Medicina Tropical 40 6 622 626 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Tuberculose pulmonar Síndrome da imunodeficiência adquirida Radiografia torácica Contagem de linfócito CD4 Pulmonary tuberculosis Acquired immunodeficiency syndrome Thoracic radiography CD4 lymphocyte count Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Tuberculose pulmonar Síndrome da imunodeficiência adquirida Radiografia torácica Contagem de linfócito CD4 Pulmonary tuberculosis Acquired immunodeficiency syndrome Thoracic radiography CD4 lymphocyte count Arctic medicine. Tropical medicine RC955-962 Guilherme Freire Garcia Alexandre Sampaio Moura Cid Sérgio Ferreira Manoel Otávio da Costa Rocha Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression Características clínicas e radiológicas da tuberculose pulmonar associada ao HIV de acordo com o nível de imunossupressão |
topic_facet |
Tuberculose pulmonar Síndrome da imunodeficiência adquirida Radiografia torácica Contagem de linfócito CD4 Pulmonary tuberculosis Acquired immunodeficiency syndrome Thoracic radiography CD4 lymphocyte count Arctic medicine. Tropical medicine RC955-962 |
description |
Medical charts and radiographs from 38 HIV-infected patients with positive cultures for Mycobacterium tuberculosis from sputum or bronchoalveolar lavage were reviewed in order to compare the clinical, radiographic, and sputum bacilloscopy characteristics of HIV-infected patients with pulmonary tuberculosis according to CD4+ lymphocyte count (CD4). The mean age of the patients was 32 years and 76% were male. The median CD4 was 106 cells/mm³ and 71% had CD4 < 200 cells/mm³. Sputum bacilloscopy was positive in 45% of the patients. Patients with CD4 < 200 cells/mm³ showed significantly less post-primary pattern (7% vs. 63%; p = 0.02) and more frequently reported weight loss (p = 0.04). Although not statistically significant, patients with lower CD4 showed lower positivity of sputum bacilloscopy (37% vs. 64%; p = 0.18). HIV-infected patients with culture-confirmed pulmonary tuberculosis had a high proportion of non-post-primary pattern in thoracic radiographs. Patients with CD4 lower than 200 cells/mm³ showed post-primary patterns less frequently and reported weight loss more frequently. Foram revisados prontuários e radiografias de 38 pacientes infectados pelo HIV com culturas de escarro ou lavado broncoalveolar positivas para Mycobacterium tuberculosis no intuito de comparar características clínicas, radiológicas e baciloscópicas de pacientes HIV-positivos com tuberculose pulmonar de acordo com a contagem de linfócitos CD4. A idade média dos pacientes foi 32 anos e 76% eram homens. Mediana de CD4 foi 106 cells/mm³ e 71% tinham CD4 <200cel/mm³. Baciloscopia de escarro foi positiva em 45%. Pacientes com CD4 <200 cel/mm³ apresentaram significativamente menos padrão pós-primário (p=0,02) e relataram emagrecimento mais freqüentemente (p=0,04). Embora sem significância estatística, pacientes com contagem mais baixa de CD4 apresentaram menor positividade na baciloscopia de escarro (p=0,18). Pacientes HIV-positivos com tuberculose pulmonar confirmada por cultura apresentam alta proporção de padrão diferentes do ... |
format |
Article in Journal/Newspaper |
author |
Guilherme Freire Garcia Alexandre Sampaio Moura Cid Sérgio Ferreira Manoel Otávio da Costa Rocha |
author_facet |
Guilherme Freire Garcia Alexandre Sampaio Moura Cid Sérgio Ferreira Manoel Otávio da Costa Rocha |
author_sort |
Guilherme Freire Garcia |
title |
Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression Características clínicas e radiológicas da tuberculose pulmonar associada ao HIV de acordo com o nível de imunossupressão |
title_short |
Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression Características clínicas e radiológicas da tuberculose pulmonar associada ao HIV de acordo com o nível de imunossupressão |
title_full |
Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression Características clínicas e radiológicas da tuberculose pulmonar associada ao HIV de acordo com o nível de imunossupressão |
title_fullStr |
Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression Características clínicas e radiológicas da tuberculose pulmonar associada ao HIV de acordo com o nível de imunossupressão |
title_full_unstemmed |
Clinical and radiographic features of HIV-related pulmonary tuberculosis according to the level of immunosuppression Características clínicas e radiológicas da tuberculose pulmonar associada ao HIV de acordo com o nível de imunossupressão |
title_sort |
clinical and radiographic features of hiv-related pulmonary tuberculosis according to the level of immunosuppression características clínicas e radiológicas da tuberculose pulmonar associada ao hiv de acordo com o nível de imunossupressão |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2007 |
url |
https://doi.org/10.1590/S0037-86822007000600004 https://doaj.org/article/af4da465699d4e5faf466461577a1850 |
geographic |
Alta Arctic |
geographic_facet |
Alta Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 40, Iss 6, Pp 622-626 (2007) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822007000600004 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 doi:10.1590/S0037-86822007000600004 0037-8682 1678-9849 https://doaj.org/article/af4da465699d4e5faf466461577a1850 |
op_doi |
https://doi.org/10.1590/S0037-86822007000600004 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
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40 |
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6 |
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622 |
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626 |
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