The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges
A considerable number of clinical trials is being conducted globally in response to the COVID-19 pandemic, including in low- and middle-income countries such as those in the Latin America and Caribbean region (LAC). Yet, an abundance of studies does not necessarily shorten the path to find safe and...
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Pan American Health Organization
2020
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Online Access: | https://doi.org/10.26633/RPSP.2020.177 https://doaj.org/article/af2e6b3715654ec99e57018e7b6ba8f9 |
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ftdoajarticles:oai:doaj.org/article:af2e6b3715654ec99e57018e7b6ba8f9 2023-05-15T15:05:25+02:00 The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges Sarah Carracedo Ana Palmero Marcie Neil Anisa Hasan-Granier Carla Saenz Ludovic Reveiz 2020-12-01T00:00:00Z https://doi.org/10.26633/RPSP.2020.177 https://doaj.org/article/af2e6b3715654ec99e57018e7b6ba8f9 EN ES PT eng spa por Pan American Health Organization https://iris.paho.org/handle/10665.2/53150 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2020.177 https://doaj.org/article/af2e6b3715654ec99e57018e7b6ba8f9 Revista Panamericana de Salud Pública, Vol 44, Iss 177, Pp 1-5 (2020) coronavirus infections clinical trial ethics research public health policy latin america caribbean region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.26633/RPSP.2020.177 2022-12-31T04:46:49Z A considerable number of clinical trials is being conducted globally in response to the COVID-19 pandemic, including in low- and middle-income countries such as those in the Latin America and Caribbean region (LAC). Yet, an abundance of studies does not necessarily shorten the path to find safe and efficacious interventions for COVID-19. We analyze the trials for COVID-19 treatment and prevention that are registered from LAC countries in the International Clinical Trials Registry Platform, and identify a trend towards small repetitive non-rigorous studies that duplicate efforts and drain limited resources without producing meaningful conclusions on the safety and efficacy of the interventions being tested. We further assess the challenges to conducting scientifically sound and socially valuable research in the LAC region in order to inform recommendations to encourage clinical trials that are most likely to produce robust evidence during the pandemic. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista Panamericana de Salud Pública 44 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish Portuguese |
topic |
coronavirus infections clinical trial ethics research public health policy latin america caribbean region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
coronavirus infections clinical trial ethics research public health policy latin america caribbean region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Sarah Carracedo Ana Palmero Marcie Neil Anisa Hasan-Granier Carla Saenz Ludovic Reveiz The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
topic_facet |
coronavirus infections clinical trial ethics research public health policy latin america caribbean region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
A considerable number of clinical trials is being conducted globally in response to the COVID-19 pandemic, including in low- and middle-income countries such as those in the Latin America and Caribbean region (LAC). Yet, an abundance of studies does not necessarily shorten the path to find safe and efficacious interventions for COVID-19. We analyze the trials for COVID-19 treatment and prevention that are registered from LAC countries in the International Clinical Trials Registry Platform, and identify a trend towards small repetitive non-rigorous studies that duplicate efforts and drain limited resources without producing meaningful conclusions on the safety and efficacy of the interventions being tested. We further assess the challenges to conducting scientifically sound and socially valuable research in the LAC region in order to inform recommendations to encourage clinical trials that are most likely to produce robust evidence during the pandemic. |
format |
Article in Journal/Newspaper |
author |
Sarah Carracedo Ana Palmero Marcie Neil Anisa Hasan-Granier Carla Saenz Ludovic Reveiz |
author_facet |
Sarah Carracedo Ana Palmero Marcie Neil Anisa Hasan-Granier Carla Saenz Ludovic Reveiz |
author_sort |
Sarah Carracedo |
title |
The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
title_short |
The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
title_full |
The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
title_fullStr |
The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
title_full_unstemmed |
The landscape of COVID-19 clinical trials in Latin America and the Caribbean: assessment and challenges |
title_sort |
landscape of covid-19 clinical trials in latin america and the caribbean: assessment and challenges |
publisher |
Pan American Health Organization |
publishDate |
2020 |
url |
https://doi.org/10.26633/RPSP.2020.177 https://doaj.org/article/af2e6b3715654ec99e57018e7b6ba8f9 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 44, Iss 177, Pp 1-5 (2020) |
op_relation |
https://iris.paho.org/handle/10665.2/53150 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2020.177 https://doaj.org/article/af2e6b3715654ec99e57018e7b6ba8f9 |
op_doi |
https://doi.org/10.26633/RPSP.2020.177 |
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Revista Panamericana de Salud Pública |
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44 |
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1 |
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1766337129702490112 |