The FML (Fucose Mannose Ligand) of Leishmania donovani: a new tool in diagnosis, prognosis, transfusional control and vaccination against human kala-azar

• Main Authors: Claris B. Palatnik de Sousa, Elza M. Gomes, Edilma Paraguai de Souza, Wania R. dos Santos, Sirley R. de Macedo, Linnete V. de Medeiros, Kleber Luz
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1996
• Subjects: Glicoconjugado; Leishmania donovani; Calazar; Transfusão de sangue; Diagnóstico; Glycoconjugate; Diagnosis; Prognosis; Kala-azar; Visceral leishmaniasis; Blood transfusion; Leishmanial antigens; Arctic medicine. Tropical medicine; RC955-962; Arctic; Azar
• Online Access: https://doaj.org/article/af00dabc9d5c41dea94565f3340b0e91

The Fucose-Mannose Ligand (FML) of Leishmania donovani is a complex glycoproteic fraction. Its potential use as a tool for diagnosis of human visceral leishmaniasis was tested with human sera from Natal, Rio Grande do Norte, Brazil. The FML-ELISA test, showed 100% sensitivity and 96% specificity, id...