Neurological manifestations of dengue in Central Brazil

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Marianna Peres Tassara, Adriana Oliveira Guilarde, Benigno Alberto Moraes da Rocha, Valéria Christina de Rezende Féres, Celina Maria Turchi Martelli
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT)
• Subjects: Dengue; Neurological; Encephalopathy; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0444-2016; https://doaj.org/article/adfce596a7e34879a94a3d86c60117bd

Abstract INTRODUCTION: The incidence of dengue has increased throughout the 2000s with a consequent global increase in atypical clinical forms. METHODS: This study reports a series of cases of neurological dengue out of 498 confirmed cases of laboratory dengue in Goiânia, Brazil. Cases were confirmed based on viral RNA detection via polymerase chain reaction or IgM antibody capture. RESULTS: Neurological symptoms occurred in 5.6% of cases, including paresthesia (3.8%), encephalitis (2%), encephalopathy (1%), seizure (0.8%), meningoencephalitis (0.4%), and paresis (0.4%). DENV-3 was the predominant circulating serotype (93%). CONCLUSIONS: We reported dengue cases with neurological manifestations in endemic area.