Role of toll-like receptor 4 in eliciting adaptive immune responses against recombinant BCG expressing the C-terminus of merozoite surface protein-1 of Plasmodium falciparum

• Published in: Asian Pacific Journal of Tropical Biomedicine
• Main Authors: Muhammad A Abbas, Rapeah Suppian
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wolters Kluwer Medknow Publications 2019
• Subjects: adaptive; bcg; immune; malaria; msp-1; tlr-4; vaccine; Arctic medicine. Tropical medicine; RC955-962; Biology (General); QH301-705.5; Arctic; Calmette
• Online Access: https://doi.org/10.4103/2221-1691.250268; https://doaj.org/article/adaf59d3baab4ae9a9ae4189071197c9

Objective: To determine the role of toll-like receptor 4 (TLR-4) in eliciting cellular and humoral immune responses against recombinant Mycobacterium bovis bacille Calmette-Guérin (rBCG) expressing the C-terminus of merozoite surface protein-1 of Plasmodium falciparum. Methods: Six groups of mice (n...