Listeriosis and AIDS: case report and literature review Listeriose e AIDS: relato de caso e revisão de literatura
Listeriosis is a not uncommon infection in humans, usually associated with immunodeficient states and with newborns. However, relatively few cases have been reported in HIV-infected patients. This scarcity of reported cases has aroused interest in the association of listerosis and AIDS. In this pape...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Main Authors: | , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Universidade de São Paulo (USP)
1992
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Subjects: | |
Online Access: | https://doi.org/10.1590/S0036-46651992000500016 https://doaj.org/article/ad5c3ab60f0641ed87a1c908cb2edfe1 |
Summary: | Listeriosis is a not uncommon infection in humans, usually associated with immunodeficient states and with newborns. However, relatively few cases have been reported in HIV-infected patients. This scarcity of reported cases has aroused interest in the association of listerosis and AIDS. In this paper we present a case of meningitis and septicemia caused by Listeria monocytogenes in a female patient with AIDS. A review of recent medical literature indicates that association of listeriosis and AIDS may be more common than it seems. Recent research in host-parasite interaction in listerial infection suggests an important role for tumor necrosis factor (TNF) and for integralin, a bacterial protein, in modulating listerial disease in AIDS patients. Inadequate diagnosis may be in part responsible for the scarcity of reports. A listeriose é uma infecção não incomum, geralmente associada com recém-nascidos e pacientes imunodeprimidos que tem sido poucas vezes encontrada em pacientes com AIDS. Esta escassez de relatos despertou o interesse de diversos investigadores. Neste artigo, os autores relatam um caso de septicemia e meningite por Listeria monocytogenes em paciente com AIDS e fazem uma revisão da literatura. Novos conhecimentos sobre a interação agente - hospedeiro nas infecções por listeria, como o papel do fator de necrose tumoral e da integralina, estão permitindo novas interpretações da aparente escassez de infecções por listeria em pacientes com AIDS. O número de relatos vem crescendo em período recente, sugerindo que a associação pode ser mais freqüente do que aparenta ser, em parte explicada por inadequação no diagnóstico. |
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