Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury
This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective da...
Published in: | International Journal of Circumpolar Health |
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ftdoajarticles:oai:doaj.org/article:ad00c100e2004691a18300d4d6a5e7d0 2023-05-15T15:07:47+02:00 Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury Clara Amalie Gade Timmermann Anna L. Choi Maria Skaalum Petersen Flemming Nielsen Esben Budtz-Jørgensen Pál Weihe Philippe Grandjean 2017-01-01T00:00:00Z https://doi.org/10.1080/22423982.2017.1406234 https://doaj.org/article/ad00c100e2004691a18300d4d6a5e7d0 EN eng Taylor & Francis Group http://dx.doi.org/10.1080/22423982.2017.1406234 https://doaj.org/toc/2242-3982 2242-3982 doi:10.1080/22423982.2017.1406234 https://doaj.org/article/ad00c100e2004691a18300d4d6a5e7d0 International Journal of Circumpolar Health, Vol 76, Iss 1 (2017) Contaminants DDE Faroe islands PCB methylmercury pilot whale sex ratio Arctic medicine. Tropical medicine RC955-962 article 2017 ftdoajarticles https://doi.org/10.1080/22423982.2017.1406234 2022-12-31T00:19:53Z This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective data from three Faroese birth cohorts, with a total of 2,152 healthy mother–child dyads recruited between 1986 and 2009. The Faroe Islands is a subarctic fishing community, where pilot whale meat and blubber are part of the traditional marine diet. Exposures were measured in maternal hair, serum or umbilical cord blood. Confounder adjusted logistic regression models were used to assess the associations between maternal exposures and the secondary sex ratio. A doubling in ΣPCB, p,p’-DDE and mercury concentrations were associated with increased odds by 8% (95% CI = 0–16%), 7% (95% CI = 0–14%) and 9% (95% CI = 2–17%), respectively, of giving birth to a boy. In conclusion, maternal exposure to ΣPCB, DDE and methylmercury was associated with a slightly increased secondary sex ratio. The impact of paternal exposures could not be taken into account and deserves attention. Article in Journal/Newspaper Arctic Circumpolar Health Faroe Islands International Journal of Circumpolar Health Subarctic Directory of Open Access Journals: DOAJ Articles Arctic Faroe Islands International Journal of Circumpolar Health 76 1 1406234 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Contaminants DDE Faroe islands PCB methylmercury pilot whale sex ratio Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Contaminants DDE Faroe islands PCB methylmercury pilot whale sex ratio Arctic medicine. Tropical medicine RC955-962 Clara Amalie Gade Timmermann Anna L. Choi Maria Skaalum Petersen Flemming Nielsen Esben Budtz-Jørgensen Pál Weihe Philippe Grandjean Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury |
topic_facet |
Contaminants DDE Faroe islands PCB methylmercury pilot whale sex ratio Arctic medicine. Tropical medicine RC955-962 |
description |
This study was undertaken to assess the potential impact of maternal exposures to polychlorinated biphenyl (PCB), dichlorodiphenyl dichloroethylene (DDE) and methylmercury on the secondary sex ratios (the ratio of male to female live births) over a span of 23 years. The study includes prospective data from three Faroese birth cohorts, with a total of 2,152 healthy mother–child dyads recruited between 1986 and 2009. The Faroe Islands is a subarctic fishing community, where pilot whale meat and blubber are part of the traditional marine diet. Exposures were measured in maternal hair, serum or umbilical cord blood. Confounder adjusted logistic regression models were used to assess the associations between maternal exposures and the secondary sex ratio. A doubling in ΣPCB, p,p’-DDE and mercury concentrations were associated with increased odds by 8% (95% CI = 0–16%), 7% (95% CI = 0–14%) and 9% (95% CI = 2–17%), respectively, of giving birth to a boy. In conclusion, maternal exposure to ΣPCB, DDE and methylmercury was associated with a slightly increased secondary sex ratio. The impact of paternal exposures could not be taken into account and deserves attention. |
format |
Article in Journal/Newspaper |
author |
Clara Amalie Gade Timmermann Anna L. Choi Maria Skaalum Petersen Flemming Nielsen Esben Budtz-Jørgensen Pál Weihe Philippe Grandjean |
author_facet |
Clara Amalie Gade Timmermann Anna L. Choi Maria Skaalum Petersen Flemming Nielsen Esben Budtz-Jørgensen Pál Weihe Philippe Grandjean |
author_sort |
Clara Amalie Gade Timmermann |
title |
Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury |
title_short |
Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury |
title_full |
Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury |
title_fullStr |
Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury |
title_full_unstemmed |
Secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury |
title_sort |
secondary sex ratio in relation to exposures to polychlorinated biphenyls, dichlorodiphenyl dichloroethylene and methylmercury |
publisher |
Taylor & Francis Group |
publishDate |
2017 |
url |
https://doi.org/10.1080/22423982.2017.1406234 https://doaj.org/article/ad00c100e2004691a18300d4d6a5e7d0 |
geographic |
Arctic Faroe Islands |
geographic_facet |
Arctic Faroe Islands |
genre |
Arctic Circumpolar Health Faroe Islands International Journal of Circumpolar Health Subarctic |
genre_facet |
Arctic Circumpolar Health Faroe Islands International Journal of Circumpolar Health Subarctic |
op_source |
International Journal of Circumpolar Health, Vol 76, Iss 1 (2017) |
op_relation |
http://dx.doi.org/10.1080/22423982.2017.1406234 https://doaj.org/toc/2242-3982 2242-3982 doi:10.1080/22423982.2017.1406234 https://doaj.org/article/ad00c100e2004691a18300d4d6a5e7d0 |
op_doi |
https://doi.org/10.1080/22423982.2017.1406234 |
container_title |
International Journal of Circumpolar Health |
container_volume |
76 |
container_issue |
1 |
container_start_page |
1406234 |
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1766339205827395584 |