A malaria transmission-directed model of mosquito life cycle and ecology
Abstract Background Malaria is a major public health issue in much of the world, and the mosquito vectors which drive transmission are key targets for interventions. Mathematical models for planning malaria eradication benefit from detailed representations of local mosquito populations, their natura...
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ftdoajarticles:oai:doaj.org/article:ac4e0d7c06b04e2586cc18b28dabc9f5 2023-05-15T15:06:58+02:00 A malaria transmission-directed model of mosquito life cycle and ecology Eckhoff Philip A 2011-10-01T00:00:00Z https://doi.org/10.1186/1475-2875-10-303 https://doaj.org/article/ac4e0d7c06b04e2586cc18b28dabc9f5 EN eng BMC http://www.malariajournal.com/content/10/1/303 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-10-303 1475-2875 https://doaj.org/article/ac4e0d7c06b04e2586cc18b28dabc9f5 Malaria Journal, Vol 10, Iss 1, p 303 (2011) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2011 ftdoajarticles https://doi.org/10.1186/1475-2875-10-303 2022-12-30T22:09:51Z Abstract Background Malaria is a major public health issue in much of the world, and the mosquito vectors which drive transmission are key targets for interventions. Mathematical models for planning malaria eradication benefit from detailed representations of local mosquito populations, their natural dynamics and their response to campaign pressures. Methods A new model is presented for mosquito population dynamics, effects of weather, and impacts of multiple simultaneous interventions. This model is then embedded in a large-scale individual-based simulation and results for local elimination of malaria are discussed. Mosquito population behaviours, such as anthropophily and indoor feeding, are included to study their effect upon the efficacy of vector control-based elimination campaigns. Results Results for vector control tools, such as bed nets, indoor spraying, larval control and space spraying, both alone and in combination, are displayed for a single-location simulation with vector species and seasonality characteristic of central Tanzania, varying baseline transmission intensity and vector bionomics. The sensitivities to habitat type, anthropophily, indoor feeding, and baseline transmission intensity are explored. Conclusions The ability to model a spectrum of local vector species with different ecologies and behaviours allows local customization of packages of interventions and exploration of the effect of proposed new tools. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 10 1 |
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English |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Eckhoff Philip A A malaria transmission-directed model of mosquito life cycle and ecology |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Malaria is a major public health issue in much of the world, and the mosquito vectors which drive transmission are key targets for interventions. Mathematical models for planning malaria eradication benefit from detailed representations of local mosquito populations, their natural dynamics and their response to campaign pressures. Methods A new model is presented for mosquito population dynamics, effects of weather, and impacts of multiple simultaneous interventions. This model is then embedded in a large-scale individual-based simulation and results for local elimination of malaria are discussed. Mosquito population behaviours, such as anthropophily and indoor feeding, are included to study their effect upon the efficacy of vector control-based elimination campaigns. Results Results for vector control tools, such as bed nets, indoor spraying, larval control and space spraying, both alone and in combination, are displayed for a single-location simulation with vector species and seasonality characteristic of central Tanzania, varying baseline transmission intensity and vector bionomics. The sensitivities to habitat type, anthropophily, indoor feeding, and baseline transmission intensity are explored. Conclusions The ability to model a spectrum of local vector species with different ecologies and behaviours allows local customization of packages of interventions and exploration of the effect of proposed new tools. |
format |
Article in Journal/Newspaper |
author |
Eckhoff Philip A |
author_facet |
Eckhoff Philip A |
author_sort |
Eckhoff Philip A |
title |
A malaria transmission-directed model of mosquito life cycle and ecology |
title_short |
A malaria transmission-directed model of mosquito life cycle and ecology |
title_full |
A malaria transmission-directed model of mosquito life cycle and ecology |
title_fullStr |
A malaria transmission-directed model of mosquito life cycle and ecology |
title_full_unstemmed |
A malaria transmission-directed model of mosquito life cycle and ecology |
title_sort |
malaria transmission-directed model of mosquito life cycle and ecology |
publisher |
BMC |
publishDate |
2011 |
url |
https://doi.org/10.1186/1475-2875-10-303 https://doaj.org/article/ac4e0d7c06b04e2586cc18b28dabc9f5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 10, Iss 1, p 303 (2011) |
op_relation |
http://www.malariajournal.com/content/10/1/303 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-10-303 1475-2875 https://doaj.org/article/ac4e0d7c06b04e2586cc18b28dabc9f5 |
op_doi |
https://doi.org/10.1186/1475-2875-10-303 |
container_title |
Malaria Journal |
container_volume |
10 |
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1 |
_version_ |
1766338545185718272 |