Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome.
Nakalanga syndrome is a condition that was described in Uganda and various other African countries decades ago. Its features include growth retardation, physical deformities, endocrine dysfunction, mental impairment, and epilepsy, amongst others. Its cause remains obscure. Nodding syndrome is a neur...
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ftdoajarticles:oai:doaj.org/article:ab8bcba74cb54d1c88122c4592bbdc83 2023-05-15T15:05:30+02:00 Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome. Kathrin Föger Gina Gora-Stahlberg James Sejvar Emilio Ovuga Louise Jilek-Aall Erich Schmutzhard Christoph Kaiser Andrea S Winkler 2017-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0005201 https://doaj.org/article/ab8bcba74cb54d1c88122c4592bbdc83 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5300103?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005201 https://doaj.org/article/ab8bcba74cb54d1c88122c4592bbdc83 PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005201 (2017) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2017 ftdoajarticles https://doi.org/10.1371/journal.pntd.0005201 2023-01-08T01:25:30Z Nakalanga syndrome is a condition that was described in Uganda and various other African countries decades ago. Its features include growth retardation, physical deformities, endocrine dysfunction, mental impairment, and epilepsy, amongst others. Its cause remains obscure. Nodding syndrome is a neurological disorder with some features in common with Nakalanga syndrome, which has been described mainly in Uganda, South Sudan, and Tanzania. It has been considered an encephalopathy affecting children who, besides head nodding attacks, can also present with stunted growth, delayed puberty, and mental impairment, amongst other symptoms. Despite active research over the last years on the pathogenesis of Nodding syndrome, to date, no convincing single cause of Nodding syndrome has been reported. In this review, by means of a thorough literature search, we compare features of both disorders. We conclude that Nakalanga and Nodding syndromes are closely related and may represent the same condition. Our findings may provide new directions in research on the cause underlying this neurological disorder. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 11 2 e0005201 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Kathrin Föger Gina Gora-Stahlberg James Sejvar Emilio Ovuga Louise Jilek-Aall Erich Schmutzhard Christoph Kaiser Andrea S Winkler Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Nakalanga syndrome is a condition that was described in Uganda and various other African countries decades ago. Its features include growth retardation, physical deformities, endocrine dysfunction, mental impairment, and epilepsy, amongst others. Its cause remains obscure. Nodding syndrome is a neurological disorder with some features in common with Nakalanga syndrome, which has been described mainly in Uganda, South Sudan, and Tanzania. It has been considered an encephalopathy affecting children who, besides head nodding attacks, can also present with stunted growth, delayed puberty, and mental impairment, amongst other symptoms. Despite active research over the last years on the pathogenesis of Nodding syndrome, to date, no convincing single cause of Nodding syndrome has been reported. In this review, by means of a thorough literature search, we compare features of both disorders. We conclude that Nakalanga and Nodding syndromes are closely related and may represent the same condition. Our findings may provide new directions in research on the cause underlying this neurological disorder. |
format |
Article in Journal/Newspaper |
author |
Kathrin Föger Gina Gora-Stahlberg James Sejvar Emilio Ovuga Louise Jilek-Aall Erich Schmutzhard Christoph Kaiser Andrea S Winkler |
author_facet |
Kathrin Föger Gina Gora-Stahlberg James Sejvar Emilio Ovuga Louise Jilek-Aall Erich Schmutzhard Christoph Kaiser Andrea S Winkler |
author_sort |
Kathrin Föger |
title |
Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome. |
title_short |
Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome. |
title_full |
Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome. |
title_fullStr |
Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome. |
title_full_unstemmed |
Nakalanga Syndrome: Clinical Characteristics, Potential Causes, and Its Relationship with Recently Described Nodding Syndrome. |
title_sort |
nakalanga syndrome: clinical characteristics, potential causes, and its relationship with recently described nodding syndrome. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2017 |
url |
https://doi.org/10.1371/journal.pntd.0005201 https://doaj.org/article/ab8bcba74cb54d1c88122c4592bbdc83 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005201 (2017) |
op_relation |
http://europepmc.org/articles/PMC5300103?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005201 https://doaj.org/article/ab8bcba74cb54d1c88122c4592bbdc83 |
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https://doi.org/10.1371/journal.pntd.0005201 |
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PLOS Neglected Tropical Diseases |
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11 |
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2 |
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e0005201 |
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1766337191995244544 |