Evaluation of laboratory markers of progression of HIV disease to death
INTRODUCTION: One of the important current problems in HIV/AIDS infection is the establishment of epidemiological and laboratorial prognostic parameters during patient follow-up. This study aimed at analyzing the evolution of laboratory tests: CD4 lymphocyte count, viral load, hemoglobin (Hb), aspar...
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ftdoajarticles:oai:doaj.org/article:ab22c47b30ff41d3a7a26438fd72c6f0 2023-05-15T15:08:07+02:00 Evaluation of laboratory markers of progression of HIV disease to death Graça Maria de Castro Viana Maria do Desterro Soares Brandão Nascimento Aila de Menezes Ferreira Érica Milena Fernandes Rabelo João Arnaud Diniz Neto Carolina de Souza Galvão Alessandro Carvalho dos Santos Onildo Martins Santos Júnior Rodrigo Artur Souza de Oliveira José Roberto Binda Júnior 2011-12-01T00:00:00Z https://doi.org/10.1590/s0037-86822011005000062 https://doaj.org/article/ab22c47b30ff41d3a7a26438fd72c6f0 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000600001&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/s0037-86822011005000062 https://doaj.org/article/ab22c47b30ff41d3a7a26438fd72c6f0 Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 6, Pp 657-660 (2011) Fatores de risco Prognóstico HIV/AIDS Arctic medicine. Tropical medicine RC955-962 article 2011 ftdoajarticles https://doi.org/10.1590/s0037-86822011005000062 2022-12-30T21:27:18Z INTRODUCTION: One of the important current problems in HIV/AIDS infection is the establishment of epidemiological and laboratorial prognostic parameters during patient follow-up. This study aimed at analyzing the evolution of laboratory tests: CD4 lymphocyte count, viral load, hemoglobin (Hb), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and the epidemiological variables sex and age as prognostic factors for survival in progression to death among AIDS patients. METHODS: A retrospective study was conducted using analysis of medical records, and prospective 24-month follow-up of patients with HIV/ AIDS attended at the President Vargas Hospital Outpatient Clinic, a reference center in HIV/ AIDS attendance in the State of Maranhão, Brazil. The study analyzed patients aged 10 to 60 years old, who manifested AIDS and who were not using antiretroviral therapy or had used it for less than 5 years. The Chi-square test was used for statistical analysis. RESULTS: The sample included 100 patients - 57 were current outpatients, and 43 had died. The variables viral load (p=0.726), ALT (p=0.314), sex (p=0.687), and age (p=0.742) were analyzed, and no evidence of association between them and worst prognosis was observed. CONCLUSIONS: A significant relation was verified between low Hb levels (p=0.000) and CD4 (p=0.000) and shorter survival. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 44 6 657 660 |
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Directory of Open Access Journals: DOAJ Articles |
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Fatores de risco Prognóstico HIV/AIDS Arctic medicine. Tropical medicine RC955-962 |
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Fatores de risco Prognóstico HIV/AIDS Arctic medicine. Tropical medicine RC955-962 Graça Maria de Castro Viana Maria do Desterro Soares Brandão Nascimento Aila de Menezes Ferreira Érica Milena Fernandes Rabelo João Arnaud Diniz Neto Carolina de Souza Galvão Alessandro Carvalho dos Santos Onildo Martins Santos Júnior Rodrigo Artur Souza de Oliveira José Roberto Binda Júnior Evaluation of laboratory markers of progression of HIV disease to death |
topic_facet |
Fatores de risco Prognóstico HIV/AIDS Arctic medicine. Tropical medicine RC955-962 |
description |
INTRODUCTION: One of the important current problems in HIV/AIDS infection is the establishment of epidemiological and laboratorial prognostic parameters during patient follow-up. This study aimed at analyzing the evolution of laboratory tests: CD4 lymphocyte count, viral load, hemoglobin (Hb), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and the epidemiological variables sex and age as prognostic factors for survival in progression to death among AIDS patients. METHODS: A retrospective study was conducted using analysis of medical records, and prospective 24-month follow-up of patients with HIV/ AIDS attended at the President Vargas Hospital Outpatient Clinic, a reference center in HIV/ AIDS attendance in the State of Maranhão, Brazil. The study analyzed patients aged 10 to 60 years old, who manifested AIDS and who were not using antiretroviral therapy or had used it for less than 5 years. The Chi-square test was used for statistical analysis. RESULTS: The sample included 100 patients - 57 were current outpatients, and 43 had died. The variables viral load (p=0.726), ALT (p=0.314), sex (p=0.687), and age (p=0.742) were analyzed, and no evidence of association between them and worst prognosis was observed. CONCLUSIONS: A significant relation was verified between low Hb levels (p=0.000) and CD4 (p=0.000) and shorter survival. |
format |
Article in Journal/Newspaper |
author |
Graça Maria de Castro Viana Maria do Desterro Soares Brandão Nascimento Aila de Menezes Ferreira Érica Milena Fernandes Rabelo João Arnaud Diniz Neto Carolina de Souza Galvão Alessandro Carvalho dos Santos Onildo Martins Santos Júnior Rodrigo Artur Souza de Oliveira José Roberto Binda Júnior |
author_facet |
Graça Maria de Castro Viana Maria do Desterro Soares Brandão Nascimento Aila de Menezes Ferreira Érica Milena Fernandes Rabelo João Arnaud Diniz Neto Carolina de Souza Galvão Alessandro Carvalho dos Santos Onildo Martins Santos Júnior Rodrigo Artur Souza de Oliveira José Roberto Binda Júnior |
author_sort |
Graça Maria de Castro Viana |
title |
Evaluation of laboratory markers of progression of HIV disease to death |
title_short |
Evaluation of laboratory markers of progression of HIV disease to death |
title_full |
Evaluation of laboratory markers of progression of HIV disease to death |
title_fullStr |
Evaluation of laboratory markers of progression of HIV disease to death |
title_full_unstemmed |
Evaluation of laboratory markers of progression of HIV disease to death |
title_sort |
evaluation of laboratory markers of progression of hiv disease to death |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2011 |
url |
https://doi.org/10.1590/s0037-86822011005000062 https://doaj.org/article/ab22c47b30ff41d3a7a26438fd72c6f0 |
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Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 44, Iss 6, Pp 657-660 (2011) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000600001&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/s0037-86822011005000062 https://doaj.org/article/ab22c47b30ff41d3a7a26438fd72c6f0 |
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https://doi.org/10.1590/s0037-86822011005000062 |
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Revista da Sociedade Brasileira de Medicina Tropical |
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44 |
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