Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report
Hump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized. In this case, we report a patient with thrombotic thrombocytopenic purpura-like syndrome following envenoming which...
Published in: | Journal of Venomous Animals and Toxins including Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:ab0518634b42430eb62b24fa883d6852 2023-05-15T15:07:42+02:00 Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report Milinda Withana Chaturaka Rodrigo Ariaranee Gnanathasan Lallindra Gooneratne 2014-08-01T00:00:00Z https://doi.org/10.1186/1678-9199-20-26 https://doaj.org/article/ab0518634b42430eb62b24fa883d6852 EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200504&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1186/1678-9199-20-26 https://doaj.org/article/ab0518634b42430eb62b24fa883d6852 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 20, Iss 0 (2014) Thrombotic thrombocytopenic purpura Hump-nosed viper Thrombotic microangiopathy Snakebite Hemolytic uremic syndrome Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2014 ftdoajarticles https://doi.org/10.1186/1678-9199-20-26 2022-12-31T08:37:57Z Hump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized. In this case, we report a patient with thrombotic thrombocytopenic purpura-like syndrome following envenoming which, to the best of our knowledge, has not been reported in the literature before. A 55-year-old woman from southern Sri Lanka presented to the local hospital 12 hours after a hump-nosed viper (Hypnale hypnale) bite. Five days later, she developed a syndrome that was characteristic of thrombotic thrombocytopenic purpura with fever, thrombocytopenia, microangiopathic hemolysis, renal impairment and neurological dysfunction in the form of confusion and coma. Her clinical syndrome and relevant laboratory parameters improved after she was treated with therapeutic plasma exchange. We compared our observations on this patient with the current literature and concluded that thrombotic thrombocytopenic purpura is a theoretically plausible yet unreported manifestation of hump-nosed viper bite up to this moment. This study also provides an important message for clinicians to look out for this complication in hump-nosed viper bites since timely treatment can be lifesaving. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 20 1 26 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Thrombotic thrombocytopenic purpura Hump-nosed viper Thrombotic microangiopathy Snakebite Hemolytic uremic syndrome Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Thrombotic thrombocytopenic purpura Hump-nosed viper Thrombotic microangiopathy Snakebite Hemolytic uremic syndrome Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 Milinda Withana Chaturaka Rodrigo Ariaranee Gnanathasan Lallindra Gooneratne Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
topic_facet |
Thrombotic thrombocytopenic purpura Hump-nosed viper Thrombotic microangiopathy Snakebite Hemolytic uremic syndrome Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Hump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized. In this case, we report a patient with thrombotic thrombocytopenic purpura-like syndrome following envenoming which, to the best of our knowledge, has not been reported in the literature before. A 55-year-old woman from southern Sri Lanka presented to the local hospital 12 hours after a hump-nosed viper (Hypnale hypnale) bite. Five days later, she developed a syndrome that was characteristic of thrombotic thrombocytopenic purpura with fever, thrombocytopenia, microangiopathic hemolysis, renal impairment and neurological dysfunction in the form of confusion and coma. Her clinical syndrome and relevant laboratory parameters improved after she was treated with therapeutic plasma exchange. We compared our observations on this patient with the current literature and concluded that thrombotic thrombocytopenic purpura is a theoretically plausible yet unreported manifestation of hump-nosed viper bite up to this moment. This study also provides an important message for clinicians to look out for this complication in hump-nosed viper bites since timely treatment can be lifesaving. |
format |
Article in Journal/Newspaper |
author |
Milinda Withana Chaturaka Rodrigo Ariaranee Gnanathasan Lallindra Gooneratne |
author_facet |
Milinda Withana Chaturaka Rodrigo Ariaranee Gnanathasan Lallindra Gooneratne |
author_sort |
Milinda Withana |
title |
Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
title_short |
Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
title_full |
Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
title_fullStr |
Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
title_full_unstemmed |
Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report |
title_sort |
presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (hypnale hypnale) bite: a case report |
publisher |
SciELO |
publishDate |
2014 |
url |
https://doi.org/10.1186/1678-9199-20-26 https://doaj.org/article/ab0518634b42430eb62b24fa883d6852 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 20, Iss 0 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200504&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1186/1678-9199-20-26 https://doaj.org/article/ab0518634b42430eb62b24fa883d6852 |
op_doi |
https://doi.org/10.1186/1678-9199-20-26 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
20 |
container_issue |
1 |
container_start_page |
26 |
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1766339143789445120 |