Zika virus infection in the genital tract of non-pregnant females: a systematic review
ABSTRACT This review provides a general overview on the positivity and persistence of Zika virus (ZIKV) in female genital tract (FGT) of non-pregnant women and animals, as well as in cell cultures, and its influence on FGT health. We performed a systematic review based on the PRISMA statement to ide...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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2020
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Online Access: | https://doi.org/10.1590/s1678-9946202062016 https://doaj.org/article/aac1a903776a45b386b4812d6ca15e0b |
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ftdoajarticles:oai:doaj.org/article:aac1a903776a45b386b4812d6ca15e0b 2024-09-09T19:26:37+00:00 Zika virus infection in the genital tract of non-pregnant females: a systematic review Fabrício Morelli Raquel Pantarotto Souza Taís Elisângela da Cruz Gabrielle Marconi Zago Ferreira Damke Edilson Damke Tamy Tuani Suehiro Vânia Ramos Sela da Silva Marcia Edilaine Lopes Consolaro 2020-03-01T00:00:00Z https://doi.org/10.1590/s1678-9946202062016 https://doaj.org/article/aac1a903776a45b386b4812d6ca15e0b EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652020000100401&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/s1678-9946202062016 https://doaj.org/article/aac1a903776a45b386b4812d6ca15e0b Revista do Instituto de Medicina Tropical de São Paulo, Vol 62 (2020) Zika virus Female Non-pregnant Genital tract Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2020 ftdoajarticles https://doi.org/10.1590/s1678-9946202062016 2024-08-05T17:49:31Z ABSTRACT This review provides a general overview on the positivity and persistence of Zika virus (ZIKV) in female genital tract (FGT) of non-pregnant women and animals, as well as in cell cultures, and its influence on FGT health. We performed a systematic review based on the PRISMA statement to identify studies focused on “Zika virus” and “non-pregnant female” in PubMed, Embase, Scopus Scholar and Web of Knowledge databases of full-text papers and abstracts published in English, with no restrictions regarding the initial date of publication, up to August 2019. Our search terms yielded 625 records, that were 108 after removal of duplicates, leaving 517 items for title and abstract reviews. Of these, 475 did not meet the inclusion criteria, leaving 42 records for full-text review and resulting in the exclusion of 6 additional records. The remaining 36 met our inclusion criteria. Variations were observed regarding the presence and persistence of ZIKV in lower and upper genital samples. However, the FGT was the place in which ZIKV RNA has been detected, sometimes for relatively long periods, even after the clearance from blood and urine. In addition to the vagina and cervix, the endometrium, uterus and ovary (oocytes and follicles) could also be involved in persistent ZIKV infections. Further prospective studies are needed to assess the effect of ZIKV on FGT health. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Prisma ENVELOPE(-58.767,-58.767,-69.200,-69.200) Revista do Instituto de Medicina Tropical de São Paulo 62 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Zika virus Female Non-pregnant Genital tract Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Zika virus Female Non-pregnant Genital tract Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Fabrício Morelli Raquel Pantarotto Souza Taís Elisângela da Cruz Gabrielle Marconi Zago Ferreira Damke Edilson Damke Tamy Tuani Suehiro Vânia Ramos Sela da Silva Marcia Edilaine Lopes Consolaro Zika virus infection in the genital tract of non-pregnant females: a systematic review |
topic_facet |
Zika virus Female Non-pregnant Genital tract Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
ABSTRACT This review provides a general overview on the positivity and persistence of Zika virus (ZIKV) in female genital tract (FGT) of non-pregnant women and animals, as well as in cell cultures, and its influence on FGT health. We performed a systematic review based on the PRISMA statement to identify studies focused on “Zika virus” and “non-pregnant female” in PubMed, Embase, Scopus Scholar and Web of Knowledge databases of full-text papers and abstracts published in English, with no restrictions regarding the initial date of publication, up to August 2019. Our search terms yielded 625 records, that were 108 after removal of duplicates, leaving 517 items for title and abstract reviews. Of these, 475 did not meet the inclusion criteria, leaving 42 records for full-text review and resulting in the exclusion of 6 additional records. The remaining 36 met our inclusion criteria. Variations were observed regarding the presence and persistence of ZIKV in lower and upper genital samples. However, the FGT was the place in which ZIKV RNA has been detected, sometimes for relatively long periods, even after the clearance from blood and urine. In addition to the vagina and cervix, the endometrium, uterus and ovary (oocytes and follicles) could also be involved in persistent ZIKV infections. Further prospective studies are needed to assess the effect of ZIKV on FGT health. |
format |
Article in Journal/Newspaper |
author |
Fabrício Morelli Raquel Pantarotto Souza Taís Elisângela da Cruz Gabrielle Marconi Zago Ferreira Damke Edilson Damke Tamy Tuani Suehiro Vânia Ramos Sela da Silva Marcia Edilaine Lopes Consolaro |
author_facet |
Fabrício Morelli Raquel Pantarotto Souza Taís Elisângela da Cruz Gabrielle Marconi Zago Ferreira Damke Edilson Damke Tamy Tuani Suehiro Vânia Ramos Sela da Silva Marcia Edilaine Lopes Consolaro |
author_sort |
Fabrício Morelli |
title |
Zika virus infection in the genital tract of non-pregnant females: a systematic review |
title_short |
Zika virus infection in the genital tract of non-pregnant females: a systematic review |
title_full |
Zika virus infection in the genital tract of non-pregnant females: a systematic review |
title_fullStr |
Zika virus infection in the genital tract of non-pregnant females: a systematic review |
title_full_unstemmed |
Zika virus infection in the genital tract of non-pregnant females: a systematic review |
title_sort |
zika virus infection in the genital tract of non-pregnant females: a systematic review |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2020 |
url |
https://doi.org/10.1590/s1678-9946202062016 https://doaj.org/article/aac1a903776a45b386b4812d6ca15e0b |
long_lat |
ENVELOPE(-58.767,-58.767,-69.200,-69.200) |
geographic |
Arctic Prisma |
geographic_facet |
Arctic Prisma |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 62 (2020) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652020000100401&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/s1678-9946202062016 https://doaj.org/article/aac1a903776a45b386b4812d6ca15e0b |
op_doi |
https://doi.org/10.1590/s1678-9946202062016 |
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Revista do Instituto de Medicina Tropical de São Paulo |
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62 |
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