SEROLOGICAL MARKERS OF VIRAL, SYPHILITIC AND TOXOPLASMIC INFECTION IN CHILDREN AND TEENAGERS WITH NEPHROTIC SYNDROME: CASE SERIES FROM MATO GROSSO STATE, BRAZIL
Some infections can be the cause of secondary nephrotic syndrome. The aim of this study was to describe the experience of a Renal Disease Reference Clinic from Central Brazil, in which serological markers of some infectious agents are systematically screened in children with nephrotic syndrome. Data...
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ftdoajarticles:oai:doaj.org/article:aa326d72605e4173b96a5d915102c167 2024-09-09T19:26:37+00:00 SEROLOGICAL MARKERS OF VIRAL, SYPHILITIC AND TOXOPLASMIC INFECTION IN CHILDREN AND TEENAGERS WITH NEPHROTIC SYNDROME: CASE SERIES FROM MATO GROSSO STATE, BRAZIL Silvania França da Silva Soares Teresinha Lermen Donatti Francisco José Dutra Souto 2014-12-01T00:00:00Z https://doi.org/10.1590/S0036-46652014000600008 https://doaj.org/article/aa326d72605e4173b96a5d915102c167 EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652014000600499&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/S0036-46652014000600008 https://doaj.org/article/aa326d72605e4173b96a5d915102c167 Revista do Instituto de Medicina Tropical de São Paulo, Vol 56, Iss 6, Pp 499-504 (2014) Nephrotic syndrome Kidney diseases/epidemiology Infant Mato Grosso State Infectious diseases Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2014 ftdoajarticles https://doi.org/10.1590/S0036-46652014000600008 2024-08-05T17:49:30Z Some infections can be the cause of secondary nephrotic syndrome. The aim of this study was to describe the experience of a Renal Disease Reference Clinic from Central Brazil, in which serological markers of some infectious agents are systematically screened in children with nephrotic syndrome. Data were obtained from the assessment of medical files of all children under fifteen years of age, who matched nephrotic syndrome criteria. Subjects were tested for IgG and IgM antibodies against T. gondii and cytomegalovirus; antibodies against Herpes simplex, hepatitis C virus and HIV; and surface antigen (HBsAg) of hepatitis B virus. The VDRL test was also performed. 169 cases were studied. The median age on the first visit was 44 months and 103 (60.9%) patients were male. Anti-CMV IgG and IgM were found in 70.4% and 4.1%, respectively. IgG and IgM against Toxoplasma gondii were present in 32.5% and 5.3%, respectively. Two patients were positive for HBsAg, but none showed markers for HIV, hepatitis C, or Treponema pallidum. IgG and IgM against herpes simplex virus were performed on 54 patients, of which 48.1% and 22.2% were positive. IgM antibodies in some children with clinical signs of recent infection suggest that these diseases may play a role in the genesis of nephrotic syndrome. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 56 6 499 504 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Nephrotic syndrome Kidney diseases/epidemiology Infant Mato Grosso State Infectious diseases Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Nephrotic syndrome Kidney diseases/epidemiology Infant Mato Grosso State Infectious diseases Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Silvania França da Silva Soares Teresinha Lermen Donatti Francisco José Dutra Souto SEROLOGICAL MARKERS OF VIRAL, SYPHILITIC AND TOXOPLASMIC INFECTION IN CHILDREN AND TEENAGERS WITH NEPHROTIC SYNDROME: CASE SERIES FROM MATO GROSSO STATE, BRAZIL |
topic_facet |
Nephrotic syndrome Kidney diseases/epidemiology Infant Mato Grosso State Infectious diseases Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Some infections can be the cause of secondary nephrotic syndrome. The aim of this study was to describe the experience of a Renal Disease Reference Clinic from Central Brazil, in which serological markers of some infectious agents are systematically screened in children with nephrotic syndrome. Data were obtained from the assessment of medical files of all children under fifteen years of age, who matched nephrotic syndrome criteria. Subjects were tested for IgG and IgM antibodies against T. gondii and cytomegalovirus; antibodies against Herpes simplex, hepatitis C virus and HIV; and surface antigen (HBsAg) of hepatitis B virus. The VDRL test was also performed. 169 cases were studied. The median age on the first visit was 44 months and 103 (60.9%) patients were male. Anti-CMV IgG and IgM were found in 70.4% and 4.1%, respectively. IgG and IgM against Toxoplasma gondii were present in 32.5% and 5.3%, respectively. Two patients were positive for HBsAg, but none showed markers for HIV, hepatitis C, or Treponema pallidum. IgG and IgM against herpes simplex virus were performed on 54 patients, of which 48.1% and 22.2% were positive. IgM antibodies in some children with clinical signs of recent infection suggest that these diseases may play a role in the genesis of nephrotic syndrome. |
format |
Article in Journal/Newspaper |
author |
Silvania França da Silva Soares Teresinha Lermen Donatti Francisco José Dutra Souto |
author_facet |
Silvania França da Silva Soares Teresinha Lermen Donatti Francisco José Dutra Souto |
author_sort |
Silvania França da Silva Soares |
title |
SEROLOGICAL MARKERS OF VIRAL, SYPHILITIC AND TOXOPLASMIC INFECTION IN CHILDREN AND TEENAGERS WITH NEPHROTIC SYNDROME: CASE SERIES FROM MATO GROSSO STATE, BRAZIL |
title_short |
SEROLOGICAL MARKERS OF VIRAL, SYPHILITIC AND TOXOPLASMIC INFECTION IN CHILDREN AND TEENAGERS WITH NEPHROTIC SYNDROME: CASE SERIES FROM MATO GROSSO STATE, BRAZIL |
title_full |
SEROLOGICAL MARKERS OF VIRAL, SYPHILITIC AND TOXOPLASMIC INFECTION IN CHILDREN AND TEENAGERS WITH NEPHROTIC SYNDROME: CASE SERIES FROM MATO GROSSO STATE, BRAZIL |
title_fullStr |
SEROLOGICAL MARKERS OF VIRAL, SYPHILITIC AND TOXOPLASMIC INFECTION IN CHILDREN AND TEENAGERS WITH NEPHROTIC SYNDROME: CASE SERIES FROM MATO GROSSO STATE, BRAZIL |
title_full_unstemmed |
SEROLOGICAL MARKERS OF VIRAL, SYPHILITIC AND TOXOPLASMIC INFECTION IN CHILDREN AND TEENAGERS WITH NEPHROTIC SYNDROME: CASE SERIES FROM MATO GROSSO STATE, BRAZIL |
title_sort |
serological markers of viral, syphilitic and toxoplasmic infection in children and teenagers with nephrotic syndrome: case series from mato grosso state, brazil |
publisher |
Universidade de São Paulo (USP) |
publishDate |
2014 |
url |
https://doi.org/10.1590/S0036-46652014000600008 https://doaj.org/article/aa326d72605e4173b96a5d915102c167 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 56, Iss 6, Pp 499-504 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652014000600499&lng=en&tlng=en https://doaj.org/toc/1678-9946 1678-9946 doi:10.1590/S0036-46652014000600008 https://doaj.org/article/aa326d72605e4173b96a5d915102c167 |
op_doi |
https://doi.org/10.1590/S0036-46652014000600008 |
container_title |
Revista do Instituto de Medicina Tropical de São Paulo |
container_volume |
56 |
container_issue |
6 |
container_start_page |
499 |
op_container_end_page |
504 |
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1809896196304535552 |