Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil.
Sporotrichosis associated with zoonotic transmission remains a relevant public health problem in Rio de Janeiro, Brazil, affecting a large at-risk population, which includes HIV-infected individuals. We assessed patients co-infected by Sporothrix spp. and HIV over time in the context of an unabated...
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ftdoajarticles:oai:doaj.org/article:a9be7e50ebd9435fa5f047770a486a88 2023-05-15T15:16:36+02:00 Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil. Dayvison Francis Saraiva Freitas Antonio Carlos Francesconi do Valle Margarete Bernardo Tavares da Silva Dayse Pereira Campos Marcelo Rosandiski Lyra Rogerio Valls de Souza Valdiléa Gonçalves Veloso Rosely Maria Zancopé-Oliveira Francisco Inácio Bastos Maria Clara Gutierrez Galhardo 2014-08-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0003110 https://doaj.org/article/a9be7e50ebd9435fa5f047770a486a88 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4148221?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003110 https://doaj.org/article/a9be7e50ebd9435fa5f047770a486a88 PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e3110 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0003110 2022-12-31T15:54:44Z Sporotrichosis associated with zoonotic transmission remains a relevant public health problem in Rio de Janeiro, Brazil, affecting a large at-risk population, which includes HIV-infected individuals. We assessed patients co-infected by Sporothrix spp. and HIV over time in the context of an unabated sporotrichosis epidemic. A retrospective cohort retrieved information from a National reference institute for infectious diseases regarding 48 patients with sporotrichosis-HIV co-infection (group 1) as well as 3,570 patients with sporotrichosis (group 2), from 1987 through March 2013. Most patients from group 1 were male (68.8%), whereas women were predominant in group 2 (69.1%; p<0.0001). Patients from group 1 were younger than those from group 2 (μ = 38.38±10.17 vs. 46.34±15.85; p<0.001) and differed from group 2 in terms of their race/ethnic background, with 70.8% non-white patients in group 1 vs. 38.6% from group 2 (p<0.0001). Close to half (∼44%) of the patients from group 1 were hospitalized due to sporotrichosis over time, whereas hospitalization was very unlikely in group 2, among whom approximately 1% were hospitalized over time. Dissemination of sporotrichosis was the main cause of hospitalization in both groups, although it was more common among hospitalized patients from group 1 (19/21 [90.5%] vs. 16/37 [43.2%]; p<0.001). Over the period under analysis, eight patients died due to sporotrichosis (3/48 vs. 5/3,570). The diagnosis of sporotrichosis elicited HIV testing and subsequent diagnosis in 19/48 patients, whereas 23/48 patients were simultaneously diagnosed with the two infections. HIV infection aggravates sporotrichosis, with a higher incidence of severe disseminated cases and a higher number of hospitalizations and deaths. Underserved populations, among whom sporotrichosis has been propagated, have been affected by different transmissible (e.g., HIV) and non-transmissible diseases. These populations should be targeted by community development programs and entitled to integrated management ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 8 8 e3110 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Dayvison Francis Saraiva Freitas Antonio Carlos Francesconi do Valle Margarete Bernardo Tavares da Silva Dayse Pereira Campos Marcelo Rosandiski Lyra Rogerio Valls de Souza Valdiléa Gonçalves Veloso Rosely Maria Zancopé-Oliveira Francisco Inácio Bastos Maria Clara Gutierrez Galhardo Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Sporotrichosis associated with zoonotic transmission remains a relevant public health problem in Rio de Janeiro, Brazil, affecting a large at-risk population, which includes HIV-infected individuals. We assessed patients co-infected by Sporothrix spp. and HIV over time in the context of an unabated sporotrichosis epidemic. A retrospective cohort retrieved information from a National reference institute for infectious diseases regarding 48 patients with sporotrichosis-HIV co-infection (group 1) as well as 3,570 patients with sporotrichosis (group 2), from 1987 through March 2013. Most patients from group 1 were male (68.8%), whereas women were predominant in group 2 (69.1%; p<0.0001). Patients from group 1 were younger than those from group 2 (μ = 38.38±10.17 vs. 46.34±15.85; p<0.001) and differed from group 2 in terms of their race/ethnic background, with 70.8% non-white patients in group 1 vs. 38.6% from group 2 (p<0.0001). Close to half (∼44%) of the patients from group 1 were hospitalized due to sporotrichosis over time, whereas hospitalization was very unlikely in group 2, among whom approximately 1% were hospitalized over time. Dissemination of sporotrichosis was the main cause of hospitalization in both groups, although it was more common among hospitalized patients from group 1 (19/21 [90.5%] vs. 16/37 [43.2%]; p<0.001). Over the period under analysis, eight patients died due to sporotrichosis (3/48 vs. 5/3,570). The diagnosis of sporotrichosis elicited HIV testing and subsequent diagnosis in 19/48 patients, whereas 23/48 patients were simultaneously diagnosed with the two infections. HIV infection aggravates sporotrichosis, with a higher incidence of severe disseminated cases and a higher number of hospitalizations and deaths. Underserved populations, among whom sporotrichosis has been propagated, have been affected by different transmissible (e.g., HIV) and non-transmissible diseases. These populations should be targeted by community development programs and entitled to integrated management ... |
format |
Article in Journal/Newspaper |
author |
Dayvison Francis Saraiva Freitas Antonio Carlos Francesconi do Valle Margarete Bernardo Tavares da Silva Dayse Pereira Campos Marcelo Rosandiski Lyra Rogerio Valls de Souza Valdiléa Gonçalves Veloso Rosely Maria Zancopé-Oliveira Francisco Inácio Bastos Maria Clara Gutierrez Galhardo |
author_facet |
Dayvison Francis Saraiva Freitas Antonio Carlos Francesconi do Valle Margarete Bernardo Tavares da Silva Dayse Pereira Campos Marcelo Rosandiski Lyra Rogerio Valls de Souza Valdiléa Gonçalves Veloso Rosely Maria Zancopé-Oliveira Francisco Inácio Bastos Maria Clara Gutierrez Galhardo |
author_sort |
Dayvison Francis Saraiva Freitas |
title |
Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil. |
title_short |
Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil. |
title_full |
Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil. |
title_fullStr |
Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil. |
title_full_unstemmed |
Sporotrichosis: an emerging neglected opportunistic infection in HIV-infected patients in Rio de Janeiro, Brazil. |
title_sort |
sporotrichosis: an emerging neglected opportunistic infection in hiv-infected patients in rio de janeiro, brazil. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0003110 https://doaj.org/article/a9be7e50ebd9435fa5f047770a486a88 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e3110 (2014) |
op_relation |
http://europepmc.org/articles/PMC4148221?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003110 https://doaj.org/article/a9be7e50ebd9435fa5f047770a486a88 |
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https://doi.org/10.1371/journal.pntd.0003110 |
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PLoS Neglected Tropical Diseases |
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8 |
container_start_page |
e3110 |
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