Neurological manifestations of dengue viral infection
Francisco Javier Carod-Artal1,21Neurology Department, Raigmore hospital, Inverness, UK; 2Universitat Internacional de Catalunya (UIC), Barcelona, Spain Abstract: Dengue is the most common mosquito-borne viral infection worldwide. There is increased evidence for dengue virus neurotropism, and neurolo...
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ftdoajarticles:oai:doaj.org/article:a9bcb8e00bcc45199a164c5ba4f7f655 2023-05-15T15:04:01+02:00 Neurological manifestations of dengue viral infection Carod-Artal FJ 2014-10-01T00:00:00Z https://doaj.org/article/a9bcb8e00bcc45199a164c5ba4f7f655 EN eng Dove Medical Press http://www.dovepress.com/neurological-manifestations-of-dengue-viral-infection-peer-reviewed-article-RRTM https://doaj.org/toc/1179-7282 1179-7282 https://doaj.org/article/a9bcb8e00bcc45199a164c5ba4f7f655 Research and Reports in Tropical Medicine, Vol 2014, Iss default, Pp 95-104 (2014) Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles 2022-12-31T06:57:24Z Francisco Javier Carod-Artal1,21Neurology Department, Raigmore hospital, Inverness, UK; 2Universitat Internacional de Catalunya (UIC), Barcelona, Spain Abstract: Dengue is the most common mosquito-borne viral infection worldwide. There is increased evidence for dengue virus neurotropism, and neurological manifestations could make part of the clinical picture of dengue virus infection in at least 0.5%–7.4% of symptomatic cases. Neurological complications have been classified into dengue virus encephalopathy, dengue virus encephalitis, immune-mediated syndromes (acute disseminated encephalomyelitis, myelitis, Guillain–Barré syndrome, neuritis brachialis, acute cerebellitis, and others), neuromuscular complications (hypokalemic paralysis, transient benign muscle dysfunction and myositis), and dengue-associated stroke. Common neuro-ophthalmic complications are maculopathy and retinal vasculopathy. Pathogenic mechanisms include systemic complications and metabolic disturbances resulting in encephalopathy, direct effect of the virus provoking encephalitis, and postinfectious immune mechanisms causing immune-mediated syndromes. Dengue viruses should be considered as a cause of neurological disorders in endemic regions. Standardized case definitions for specific neurological complications are still needed. Keywords: encephalitis, encephalopathy, dengue fever, neurological complications Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Barré ENVELOPE(-68.550,-68.550,-67.500,-67.500) |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 |
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Arctic medicine. Tropical medicine RC955-962 Carod-Artal FJ Neurological manifestations of dengue viral infection |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 |
description |
Francisco Javier Carod-Artal1,21Neurology Department, Raigmore hospital, Inverness, UK; 2Universitat Internacional de Catalunya (UIC), Barcelona, Spain Abstract: Dengue is the most common mosquito-borne viral infection worldwide. There is increased evidence for dengue virus neurotropism, and neurological manifestations could make part of the clinical picture of dengue virus infection in at least 0.5%–7.4% of symptomatic cases. Neurological complications have been classified into dengue virus encephalopathy, dengue virus encephalitis, immune-mediated syndromes (acute disseminated encephalomyelitis, myelitis, Guillain–Barré syndrome, neuritis brachialis, acute cerebellitis, and others), neuromuscular complications (hypokalemic paralysis, transient benign muscle dysfunction and myositis), and dengue-associated stroke. Common neuro-ophthalmic complications are maculopathy and retinal vasculopathy. Pathogenic mechanisms include systemic complications and metabolic disturbances resulting in encephalopathy, direct effect of the virus provoking encephalitis, and postinfectious immune mechanisms causing immune-mediated syndromes. Dengue viruses should be considered as a cause of neurological disorders in endemic regions. Standardized case definitions for specific neurological complications are still needed. Keywords: encephalitis, encephalopathy, dengue fever, neurological complications |
format |
Article in Journal/Newspaper |
author |
Carod-Artal FJ |
author_facet |
Carod-Artal FJ |
author_sort |
Carod-Artal FJ |
title |
Neurological manifestations of dengue viral infection |
title_short |
Neurological manifestations of dengue viral infection |
title_full |
Neurological manifestations of dengue viral infection |
title_fullStr |
Neurological manifestations of dengue viral infection |
title_full_unstemmed |
Neurological manifestations of dengue viral infection |
title_sort |
neurological manifestations of dengue viral infection |
publisher |
Dove Medical Press |
publishDate |
2014 |
url |
https://doaj.org/article/a9bcb8e00bcc45199a164c5ba4f7f655 |
long_lat |
ENVELOPE(-68.550,-68.550,-67.500,-67.500) |
geographic |
Arctic Barré |
geographic_facet |
Arctic Barré |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Research and Reports in Tropical Medicine, Vol 2014, Iss default, Pp 95-104 (2014) |
op_relation |
http://www.dovepress.com/neurological-manifestations-of-dengue-viral-infection-peer-reviewed-article-RRTM https://doaj.org/toc/1179-7282 1179-7282 https://doaj.org/article/a9bcb8e00bcc45199a164c5ba4f7f655 |
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1766335847389462528 |