Genome-wide association meta-analysis yields 20 loci associated with gallstone disease
Genome-wide association studies have so far identified eight risk loci for gallstone disease. Here, the authors perform meta-analysis in cohorts from Iceland and the UK which reveals further 21 common and low-frequency risk variants that highlight the role of bile acid homeostasis in gallstone disea...
Published in: | Nature Communications |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doi.org/10.1038/s41467-018-07460-y https://doaj.org/article/a99d2484d9a048f3ab41a8a1d889ba68 |
Summary: | Genome-wide association studies have so far identified eight risk loci for gallstone disease. Here, the authors perform meta-analysis in cohorts from Iceland and the UK which reveals further 21 common and low-frequency risk variants that highlight the role of bile acid homeostasis in gallstone disease. |
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