Metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity
Introduction: The postprandial stage is associated with the increase of markers related to cardiovascular risk, and its intensity depends on the metabolic state. Objective: To determine the impact of a high-fat meal intake on the metabolic and inflammatory profile, and its relationship to abdominal...
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ftdoajarticles:oai:doaj.org/article:a96c4fdeaf86451bb3743c666b3038b4 2023-05-15T15:09:42+02:00 Metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity Alicia Norma Alayón Ana Patricia Rivadeneira Carlos Herrera Heidy Guzmán Dioneris Arellano Isabella Echeverri 2018-05-01T00:00:00Z https://doi.org/10.7705/biomedica.v38i0.3911 https://doaj.org/article/a96c4fdeaf86451bb3743c666b3038b4 EN ES eng spa Instituto Nacional de Salud https://www.revistabiomedica.org/index.php/biomedica/article/view/3911 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.v38i0.3911 https://doaj.org/article/a96c4fdeaf86451bb3743c666b3038b4 Biomédica: revista del Instituto Nacional de Salud, Vol 38, Iss 0, Pp 93-100 (2018) obesidad inflamación periodo posprandial dieta rica en grasa resistencia a la insulina lipopolisacáridos Medicine R Arctic medicine. Tropical medicine RC955-962 article 2018 ftdoajarticles https://doi.org/10.7705/biomedica.v38i0.3911 2022-12-31T02:08:44Z Introduction: The postprandial stage is associated with the increase of markers related to cardiovascular risk, and its intensity depends on the metabolic state. Objective: To determine the impact of a high-fat meal intake on the metabolic and inflammatory profile, and its relationship to abdominal obesity. Materials and methods: This clinical trial included 42 individuals (21 with abdominal obesity). We measured glucose, insulin, lipid profile, reactive C protein, lipopolysaccharides, and interleukin 6 in fasting blood, and four hours after eating. Results: Besides obesity, we found insulin resistance and higher levels of fasting triacylglycerides and C-reactive protein. There were higher postprandial responses to glucose, insulin, and triacylglycerides. Interleukin 6 decreased in the non-obese group, and lipopolysaccharides increased in both groups. Conclusions: A saturated high-fat food intake produced a greater impact on the glycemic variables in the group with obesity, while it affected the lipids in both groups. However, the increase of triacylglycerides was higher in the presence of a high basal concentration, and it promoted the increase of lipopolysaccharides. The basal and postprandial inflammatory state affected the group with obesity more. The postprandial moment reflected the most frequent state of the individuals on a normal day and evidenced the capacity of the metabolic response to food intake, as well as early metabolic risk states. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Biomédica 38 100 107 |
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Directory of Open Access Journals: DOAJ Articles |
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language |
English Spanish |
topic |
obesidad inflamación periodo posprandial dieta rica en grasa resistencia a la insulina lipopolisacáridos Medicine R Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
obesidad inflamación periodo posprandial dieta rica en grasa resistencia a la insulina lipopolisacáridos Medicine R Arctic medicine. Tropical medicine RC955-962 Alicia Norma Alayón Ana Patricia Rivadeneira Carlos Herrera Heidy Guzmán Dioneris Arellano Isabella Echeverri Metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity |
topic_facet |
obesidad inflamación periodo posprandial dieta rica en grasa resistencia a la insulina lipopolisacáridos Medicine R Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction: The postprandial stage is associated with the increase of markers related to cardiovascular risk, and its intensity depends on the metabolic state. Objective: To determine the impact of a high-fat meal intake on the metabolic and inflammatory profile, and its relationship to abdominal obesity. Materials and methods: This clinical trial included 42 individuals (21 with abdominal obesity). We measured glucose, insulin, lipid profile, reactive C protein, lipopolysaccharides, and interleukin 6 in fasting blood, and four hours after eating. Results: Besides obesity, we found insulin resistance and higher levels of fasting triacylglycerides and C-reactive protein. There were higher postprandial responses to glucose, insulin, and triacylglycerides. Interleukin 6 decreased in the non-obese group, and lipopolysaccharides increased in both groups. Conclusions: A saturated high-fat food intake produced a greater impact on the glycemic variables in the group with obesity, while it affected the lipids in both groups. However, the increase of triacylglycerides was higher in the presence of a high basal concentration, and it promoted the increase of lipopolysaccharides. The basal and postprandial inflammatory state affected the group with obesity more. The postprandial moment reflected the most frequent state of the individuals on a normal day and evidenced the capacity of the metabolic response to food intake, as well as early metabolic risk states. |
format |
Article in Journal/Newspaper |
author |
Alicia Norma Alayón Ana Patricia Rivadeneira Carlos Herrera Heidy Guzmán Dioneris Arellano Isabella Echeverri |
author_facet |
Alicia Norma Alayón Ana Patricia Rivadeneira Carlos Herrera Heidy Guzmán Dioneris Arellano Isabella Echeverri |
author_sort |
Alicia Norma Alayón |
title |
Metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity |
title_short |
Metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity |
title_full |
Metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity |
title_fullStr |
Metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity |
title_full_unstemmed |
Metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity |
title_sort |
metabolic and inflammatory postprandial effect of a highly saturated fat meal and its relationship to abdominal obesity |
publisher |
Instituto Nacional de Salud |
publishDate |
2018 |
url |
https://doi.org/10.7705/biomedica.v38i0.3911 https://doaj.org/article/a96c4fdeaf86451bb3743c666b3038b4 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Biomédica: revista del Instituto Nacional de Salud, Vol 38, Iss 0, Pp 93-100 (2018) |
op_relation |
https://www.revistabiomedica.org/index.php/biomedica/article/view/3911 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.v38i0.3911 https://doaj.org/article/a96c4fdeaf86451bb3743c666b3038b4 |
op_doi |
https://doi.org/10.7705/biomedica.v38i0.3911 |
container_title |
Biomédica |
container_volume |
38 |
container_start_page |
100 |
op_container_end_page |
107 |
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1766340840461959168 |