Oral manifestations in chikungunya patients: A systematic review
Background Chikungunya fever is considered an abrupt onset arbovirus transmitted by mosquitoes, mainly Aedes aegypti and Aedes albopictus. The disease has a significant impact on the quality of life of affected persons, and many of its numerous symptoms have not yet been properly clarified, such as...
Main Authors: | , , , , |
---|---|
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/a746aaa959434719886383ef674e18d9 |
id |
ftdoajarticles:oai:doaj.org/article:a746aaa959434719886383ef674e18d9 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:a746aaa959434719886383ef674e18d9 2023-05-15T15:15:36+02:00 Oral manifestations in chikungunya patients: A systematic review Daniela Brostolin da Costa Alessandro Diogo De-Carli Livia Fernandes Probst Antonio José Grande Ana Tereza Gomes Guerrero 2021-06-01T00:00:00Z https://doaj.org/article/a746aaa959434719886383ef674e18d9 EN eng Public Library of Science (PLoS) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191910/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 https://doaj.org/article/a746aaa959434719886383ef674e18d9 PLoS Neglected Tropical Diseases, Vol 15, Iss 6 (2021) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2021 ftdoajarticles 2022-12-31T06:52:07Z Background Chikungunya fever is considered an abrupt onset arbovirus transmitted by mosquitoes, mainly Aedes aegypti and Aedes albopictus. The disease has a significant impact on the quality of life of affected persons, and many of its numerous symptoms have not yet been properly clarified, such as the manifestations that can occur in the oral cavity. The aim of this study was to identify the main oral manifestations related to chikungunya fever, as well as describe the demographic characteristics of patients, by conducting a systematic review of the literature. Methods and findings Searches were performed in MEDLINE (PubMed), Embase (Elsevier), LILACS (VHL), Cochrane Library, Scopus, and CAPES electronic databases for theses and dissertations published up to January 16, 2021 without language and date restrictions. Additional manual searches of gray literature, reference list, and Google Scholar were carried out. We included 27 studies highlighting mainly oral manifestations that cause masticatory discomfort such as ulcers and oral thrush, gingival bleeding, pain and burning of the oral mucous membranes, temporomandibular joint (TMJ) arthralgia, opportunistic infections, and changes in taste. Conclusions There seems to be a predominance of oral manifestations that cause discomfort when chewing, such as ulcerations in the acute phase of the disease, with complete remission within 3 to 10 days after the onset, apparently mostly affecting women and older persons. These oral manifestations can be compatible with basic viral infections related to inflammatory response and transitory immunosuppression. Author summary Since its resurgence in 2004, control of the transmission of chikungunya fever has become a challenge to public health worldwide. As it is capable of diminishing the quality of life of infected persons, it has aroused interest in the scientific community in developing more in-depth studies. Many of its numerous symptoms have not yet been properly clarified, such as the manifestations that can occur in the ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Daniela Brostolin da Costa Alessandro Diogo De-Carli Livia Fernandes Probst Antonio José Grande Ana Tereza Gomes Guerrero Oral manifestations in chikungunya patients: A systematic review |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Chikungunya fever is considered an abrupt onset arbovirus transmitted by mosquitoes, mainly Aedes aegypti and Aedes albopictus. The disease has a significant impact on the quality of life of affected persons, and many of its numerous symptoms have not yet been properly clarified, such as the manifestations that can occur in the oral cavity. The aim of this study was to identify the main oral manifestations related to chikungunya fever, as well as describe the demographic characteristics of patients, by conducting a systematic review of the literature. Methods and findings Searches were performed in MEDLINE (PubMed), Embase (Elsevier), LILACS (VHL), Cochrane Library, Scopus, and CAPES electronic databases for theses and dissertations published up to January 16, 2021 without language and date restrictions. Additional manual searches of gray literature, reference list, and Google Scholar were carried out. We included 27 studies highlighting mainly oral manifestations that cause masticatory discomfort such as ulcers and oral thrush, gingival bleeding, pain and burning of the oral mucous membranes, temporomandibular joint (TMJ) arthralgia, opportunistic infections, and changes in taste. Conclusions There seems to be a predominance of oral manifestations that cause discomfort when chewing, such as ulcerations in the acute phase of the disease, with complete remission within 3 to 10 days after the onset, apparently mostly affecting women and older persons. These oral manifestations can be compatible with basic viral infections related to inflammatory response and transitory immunosuppression. Author summary Since its resurgence in 2004, control of the transmission of chikungunya fever has become a challenge to public health worldwide. As it is capable of diminishing the quality of life of infected persons, it has aroused interest in the scientific community in developing more in-depth studies. Many of its numerous symptoms have not yet been properly clarified, such as the manifestations that can occur in the ... |
format |
Article in Journal/Newspaper |
author |
Daniela Brostolin da Costa Alessandro Diogo De-Carli Livia Fernandes Probst Antonio José Grande Ana Tereza Gomes Guerrero |
author_facet |
Daniela Brostolin da Costa Alessandro Diogo De-Carli Livia Fernandes Probst Antonio José Grande Ana Tereza Gomes Guerrero |
author_sort |
Daniela Brostolin da Costa |
title |
Oral manifestations in chikungunya patients: A systematic review |
title_short |
Oral manifestations in chikungunya patients: A systematic review |
title_full |
Oral manifestations in chikungunya patients: A systematic review |
title_fullStr |
Oral manifestations in chikungunya patients: A systematic review |
title_full_unstemmed |
Oral manifestations in chikungunya patients: A systematic review |
title_sort |
oral manifestations in chikungunya patients: a systematic review |
publisher |
Public Library of Science (PLoS) |
publishDate |
2021 |
url |
https://doaj.org/article/a746aaa959434719886383ef674e18d9 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 15, Iss 6 (2021) |
op_relation |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191910/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 https://doaj.org/article/a746aaa959434719886383ef674e18d9 |
_version_ |
1766345960898691072 |