Identification of the Mycobacterium tuberculosis Beijing lineage in Ecuador
Introduction: Mycobacterium tuberculosis Beijing lineage isolates are considered to be especially virulent, transmissible and prone to acquire resistances. Beijing strains have been reported worldwide, but studies in Latin America are still scarce. The only multinational study performed in the regio...
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ftdoajarticles:oai:doaj.org/article:a66deaef16b2429cbea6fd8da7ae53b4 2023-05-15T15:07:21+02:00 Identification of the Mycobacterium tuberculosis Beijing lineage in Ecuador Patricia Jiménez Karina Calvopiña Diana Herrera Carlos Rojas Laura Pérez-Lago Marcelo Grijalva Remedios Guna Darío García-de Viedma 2017-06-01T00:00:00Z https://doi.org/10.7705/biomedica.v37i3.3450 https://doaj.org/article/a66deaef16b2429cbea6fd8da7ae53b4 EN ES eng spa Instituto Nacional de Salud https://www.revistabiomedica.org/index.php/biomedica/article/view/3450 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.v37i3.3450 https://doaj.org/article/a66deaef16b2429cbea6fd8da7ae53b4 Biomédica: revista del Instituto Nacional de Salud, Vol 37, Iss 2, Pp 233-237 (2017) Mycobacterium tuberculosis tuberculosis case reports virulence molecular epidemiology Ecuador Medicine R Arctic medicine. Tropical medicine RC955-962 article 2017 ftdoajarticles https://doi.org/10.7705/biomedica.v37i3.3450 2022-12-30T23:55:57Z Introduction: Mycobacterium tuberculosis Beijing lineage isolates are considered to be especially virulent, transmissible and prone to acquire resistances. Beijing strains have been reported worldwide, but studies in Latin America are still scarce. The only multinational study performed in the region indicated a heterogeneous distribution for this lineage, which was absent in Chile, Colombia and Ecuador, although further studies found the lineage in Chile and Colombia. Objective: To search for the presence of the Beijing lineage in Ecuador, the only country in the region where it remains unreported. Materials and methods: We obtained a convenience sample (2006-2012) from two hospitals covering different populations. The isolates were genotyped using 24-MIRU-VNTR. Lineages were assigned by comparing their patterns to those in the MIRU-VNTRplus platform. Isolates belonging to the Beijing lineage were confirmed by allele-specific PCR. Results: We identified the first Beijing isolate in Ecuador in an unexpected epidemiological scenario: A patient was infected in the Andean region, in a population with low mobility and far from the borders of the neighboring countries where Beijing strains had been previously reported. Conclusion: This is the first report of the presence of the Beijing lineage in Ecuador in an unusual epidemiological context that deserves special attention. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Biomédica 37 2 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish |
topic |
Mycobacterium tuberculosis tuberculosis case reports virulence molecular epidemiology Ecuador Medicine R Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Mycobacterium tuberculosis tuberculosis case reports virulence molecular epidemiology Ecuador Medicine R Arctic medicine. Tropical medicine RC955-962 Patricia Jiménez Karina Calvopiña Diana Herrera Carlos Rojas Laura Pérez-Lago Marcelo Grijalva Remedios Guna Darío García-de Viedma Identification of the Mycobacterium tuberculosis Beijing lineage in Ecuador |
topic_facet |
Mycobacterium tuberculosis tuberculosis case reports virulence molecular epidemiology Ecuador Medicine R Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction: Mycobacterium tuberculosis Beijing lineage isolates are considered to be especially virulent, transmissible and prone to acquire resistances. Beijing strains have been reported worldwide, but studies in Latin America are still scarce. The only multinational study performed in the region indicated a heterogeneous distribution for this lineage, which was absent in Chile, Colombia and Ecuador, although further studies found the lineage in Chile and Colombia. Objective: To search for the presence of the Beijing lineage in Ecuador, the only country in the region where it remains unreported. Materials and methods: We obtained a convenience sample (2006-2012) from two hospitals covering different populations. The isolates were genotyped using 24-MIRU-VNTR. Lineages were assigned by comparing their patterns to those in the MIRU-VNTRplus platform. Isolates belonging to the Beijing lineage were confirmed by allele-specific PCR. Results: We identified the first Beijing isolate in Ecuador in an unexpected epidemiological scenario: A patient was infected in the Andean region, in a population with low mobility and far from the borders of the neighboring countries where Beijing strains had been previously reported. Conclusion: This is the first report of the presence of the Beijing lineage in Ecuador in an unusual epidemiological context that deserves special attention. |
format |
Article in Journal/Newspaper |
author |
Patricia Jiménez Karina Calvopiña Diana Herrera Carlos Rojas Laura Pérez-Lago Marcelo Grijalva Remedios Guna Darío García-de Viedma |
author_facet |
Patricia Jiménez Karina Calvopiña Diana Herrera Carlos Rojas Laura Pérez-Lago Marcelo Grijalva Remedios Guna Darío García-de Viedma |
author_sort |
Patricia Jiménez |
title |
Identification of the Mycobacterium tuberculosis Beijing lineage in Ecuador |
title_short |
Identification of the Mycobacterium tuberculosis Beijing lineage in Ecuador |
title_full |
Identification of the Mycobacterium tuberculosis Beijing lineage in Ecuador |
title_fullStr |
Identification of the Mycobacterium tuberculosis Beijing lineage in Ecuador |
title_full_unstemmed |
Identification of the Mycobacterium tuberculosis Beijing lineage in Ecuador |
title_sort |
identification of the mycobacterium tuberculosis beijing lineage in ecuador |
publisher |
Instituto Nacional de Salud |
publishDate |
2017 |
url |
https://doi.org/10.7705/biomedica.v37i3.3450 https://doaj.org/article/a66deaef16b2429cbea6fd8da7ae53b4 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Biomédica: revista del Instituto Nacional de Salud, Vol 37, Iss 2, Pp 233-237 (2017) |
op_relation |
https://www.revistabiomedica.org/index.php/biomedica/article/view/3450 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.v37i3.3450 https://doaj.org/article/a66deaef16b2429cbea6fd8da7ae53b4 |
op_doi |
https://doi.org/10.7705/biomedica.v37i3.3450 |
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Biomédica |
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37 |
container_issue |
2 |
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1766338877951311872 |