Treatment in Infections by Enterobacterales Producing Extended Spectrum Betalactamase. Systematic Review
Extended spectrum beta-lactamases producing Enterobacterales have become pandemic worldwide representing a major public health threat due to poor outcomes and high mortality associated with infections by these bacteria, consequently it is essential to conduct a systematic review to document the anti...
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Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
2021
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ftdoajarticles:oai:doaj.org/article:a652dc95f3b541a9842ea5c3d76b7fac 2023-10-09T21:49:08+02:00 Treatment in Infections by Enterobacterales Producing Extended Spectrum Betalactamase. Systematic Review Carli Samira Aziz Delgado José Andrés Mendoza Gaviria 2021-10-01T00:00:00Z https://doi.org/10.5281/zenodo.5546295 https://doaj.org/article/a652dc95f3b541a9842ea5c3d76b7fac EN ES eng spa Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales https://produccioncientificaluz.org/index.php/kasmera/article/view/35056 https://doaj.org/toc/0075-5222 https://doaj.org/toc/2477-9628 doi:10.5281/zenodo.5546295 0075-5222 2477-9628 https://doaj.org/article/a652dc95f3b541a9842ea5c3d76b7fac Kasmera, Vol 49, Iss 2 (2021) Enterobacterales infection beta-lactamase beta-lactamase inhibitors Enterobacteriaceae/enzymology therapeutics Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2021 ftdoajarticles https://doi.org/10.5281/zenodo.5546295 2023-09-10T00:44:08Z Extended spectrum beta-lactamases producing Enterobacterales have become pandemic worldwide representing a major public health threat due to poor outcomes and high mortality associated with infections by these bacteria, consequently it is essential to conduct a systematic review to document the antibiotic combination used to fight infections, in order to categorize and sort the most widely used treatments and determine the most effective ones. The electronic search was conducted since June 2020 until August 2020. The databases used were PubMed, Virtual Health Library, ScienceDirect and the Cochrane library; the following Medical Subject Headings (MESH) were used: “Enterobacterales”, “infection”, “beta-lactamase”, “beta-lactamase inhibitors”, “therapeutics”, “Enterobacteriaceae/enzymology”. The electronic search resulted in 1.526 articles meeting the general criteria, 1.493 articles were excluded; only 35 articles met all the inclusion criteria. there is basically no tangible difference between treatment with beta-lactam antibiotics (either combinations or carbapenem), fluoroquinolones, tetracyclines and Fosfomycin in patients without any pre-existing antibiotic resistance. It is required developing antibiotics, with the understanding that the microorganism will respond to them and resistance will develop (an evolutionary fact). Therefore, efforts to develop antibiotics and study mechanisms of resistance should be continuous, resilient, and steady Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
institution |
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collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish |
topic |
Enterobacterales infection beta-lactamase beta-lactamase inhibitors Enterobacteriaceae/enzymology therapeutics Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Enterobacterales infection beta-lactamase beta-lactamase inhibitors Enterobacteriaceae/enzymology therapeutics Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Carli Samira Aziz Delgado José Andrés Mendoza Gaviria Treatment in Infections by Enterobacterales Producing Extended Spectrum Betalactamase. Systematic Review |
topic_facet |
Enterobacterales infection beta-lactamase beta-lactamase inhibitors Enterobacteriaceae/enzymology therapeutics Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Extended spectrum beta-lactamases producing Enterobacterales have become pandemic worldwide representing a major public health threat due to poor outcomes and high mortality associated with infections by these bacteria, consequently it is essential to conduct a systematic review to document the antibiotic combination used to fight infections, in order to categorize and sort the most widely used treatments and determine the most effective ones. The electronic search was conducted since June 2020 until August 2020. The databases used were PubMed, Virtual Health Library, ScienceDirect and the Cochrane library; the following Medical Subject Headings (MESH) were used: “Enterobacterales”, “infection”, “beta-lactamase”, “beta-lactamase inhibitors”, “therapeutics”, “Enterobacteriaceae/enzymology”. The electronic search resulted in 1.526 articles meeting the general criteria, 1.493 articles were excluded; only 35 articles met all the inclusion criteria. there is basically no tangible difference between treatment with beta-lactam antibiotics (either combinations or carbapenem), fluoroquinolones, tetracyclines and Fosfomycin in patients without any pre-existing antibiotic resistance. It is required developing antibiotics, with the understanding that the microorganism will respond to them and resistance will develop (an evolutionary fact). Therefore, efforts to develop antibiotics and study mechanisms of resistance should be continuous, resilient, and steady |
format |
Article in Journal/Newspaper |
author |
Carli Samira Aziz Delgado José Andrés Mendoza Gaviria |
author_facet |
Carli Samira Aziz Delgado José Andrés Mendoza Gaviria |
author_sort |
Carli Samira Aziz Delgado |
title |
Treatment in Infections by Enterobacterales Producing Extended Spectrum Betalactamase. Systematic Review |
title_short |
Treatment in Infections by Enterobacterales Producing Extended Spectrum Betalactamase. Systematic Review |
title_full |
Treatment in Infections by Enterobacterales Producing Extended Spectrum Betalactamase. Systematic Review |
title_fullStr |
Treatment in Infections by Enterobacterales Producing Extended Spectrum Betalactamase. Systematic Review |
title_full_unstemmed |
Treatment in Infections by Enterobacterales Producing Extended Spectrum Betalactamase. Systematic Review |
title_sort |
treatment in infections by enterobacterales producing extended spectrum betalactamase. systematic review |
publisher |
Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales |
publishDate |
2021 |
url |
https://doi.org/10.5281/zenodo.5546295 https://doaj.org/article/a652dc95f3b541a9842ea5c3d76b7fac |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Kasmera, Vol 49, Iss 2 (2021) |
op_relation |
https://produccioncientificaluz.org/index.php/kasmera/article/view/35056 https://doaj.org/toc/0075-5222 https://doaj.org/toc/2477-9628 doi:10.5281/zenodo.5546295 0075-5222 2477-9628 https://doaj.org/article/a652dc95f3b541a9842ea5c3d76b7fac |
op_doi |
https://doi.org/10.5281/zenodo.5546295 |
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1779312171889459200 |