Distinct cytokine profiles in malaria coinfections: A systematic review
Background Few data exist on the distinct cytokine profiles of individuals with malaria coinfections and other diseases. This study focuses on data collation of distinct cytokine profiles between individuals with malaria coinfections and monoinfections to provide evidence for further diagnostic or p...
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ftdoajarticles:oai:doaj.org/article:a57e8744a2fb462fa32b518083b3aaa5 2023-05-15T15:14:13+02:00 Distinct cytokine profiles in malaria coinfections: A systematic review Manas Kotepui Wanida Mala Pattamaporn Kwankaew Kwuntida Uthaisar Kotepui Frederick Ramirez Masangkay Polrat Wilairatana 2023-01-01T00:00:00Z https://doaj.org/article/a57e8744a2fb462fa32b518083b3aaa5 EN eng Public Library of Science (PLoS) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886258/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 https://doaj.org/article/a57e8744a2fb462fa32b518083b3aaa5 PLoS Neglected Tropical Diseases, Vol 17, Iss 1 (2023) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2023 ftdoajarticles 2023-02-05T01:26:50Z Background Few data exist on the distinct cytokine profiles of individuals with malaria coinfections and other diseases. This study focuses on data collation of distinct cytokine profiles between individuals with malaria coinfections and monoinfections to provide evidence for further diagnostic or prognostic studies. Methods We searched five medical databases, including Embase, MEDLINE, PubMed, Ovid, and Scopus, for articles on cytokines in malaria coinfections published from January 1, 1983 to May 3, 2022, after which the distinct cytokine patterns between malaria coinfection and monoinfection were illustrated in heat maps. Results Preliminary searches identified 2127 articles, of which 34 were included in the systematic review. Distinct cytokine profiles in malaria coinfections with bacteremia; HIV; HBV; dengue; filariasis; intestinal parasites; and schistosomiasis were tumor necrosis factor (TNF), interferon (IFN)-γ, IFN-α, interleukin (IL)-1, IL-1 receptor antagonist (Ra), IL-4, IL-7, IL-12, IL-15, IL-17; TNF, IL-1Ra, IL-4, IL-10, IL-12, IL-18, CCL3, CCL5, CXCL8, CXCL9, CXCL11, granulocyte colony-stimulating factor (G-CSF); TNF, IFN-γ, IL-4, IL-6, IL-10, IL-12, CCL2; IFN-γ, IL-1, IL-4, IL-6, IL-10, IL-12, IL-13, IL-17, CCL2, CCL3, CCL4, G-CSF; IL-1Ra, IL-10, CXCL5, CXCL8, CXCL10; TNF, IL-2, IL-4, IL-6, IL-10; and TNF, IFN-γ, IL-4, IL-5, IL-10, transforming growth factor-β, CXCL8, respectively. Conclusion This systematic review provides information on distinct cytokine profiles of malaria coinfections and malaria monoinfections. Further studies should investigate whether specific cytokines for each coinfection type could serve as essential diagnostic or prognostic biomarkers for malaria coinfections. Author summary Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium knowlesi infections all cause malaria, an acute febrile illness that is transmitted to people by the bites of infected female Anopheles mosquitoes. Following malaria infections in people, an individual’s ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Manas Kotepui Wanida Mala Pattamaporn Kwankaew Kwuntida Uthaisar Kotepui Frederick Ramirez Masangkay Polrat Wilairatana Distinct cytokine profiles in malaria coinfections: A systematic review |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Background Few data exist on the distinct cytokine profiles of individuals with malaria coinfections and other diseases. This study focuses on data collation of distinct cytokine profiles between individuals with malaria coinfections and monoinfections to provide evidence for further diagnostic or prognostic studies. Methods We searched five medical databases, including Embase, MEDLINE, PubMed, Ovid, and Scopus, for articles on cytokines in malaria coinfections published from January 1, 1983 to May 3, 2022, after which the distinct cytokine patterns between malaria coinfection and monoinfection were illustrated in heat maps. Results Preliminary searches identified 2127 articles, of which 34 were included in the systematic review. Distinct cytokine profiles in malaria coinfections with bacteremia; HIV; HBV; dengue; filariasis; intestinal parasites; and schistosomiasis were tumor necrosis factor (TNF), interferon (IFN)-γ, IFN-α, interleukin (IL)-1, IL-1 receptor antagonist (Ra), IL-4, IL-7, IL-12, IL-15, IL-17; TNF, IL-1Ra, IL-4, IL-10, IL-12, IL-18, CCL3, CCL5, CXCL8, CXCL9, CXCL11, granulocyte colony-stimulating factor (G-CSF); TNF, IFN-γ, IL-4, IL-6, IL-10, IL-12, CCL2; IFN-γ, IL-1, IL-4, IL-6, IL-10, IL-12, IL-13, IL-17, CCL2, CCL3, CCL4, G-CSF; IL-1Ra, IL-10, CXCL5, CXCL8, CXCL10; TNF, IL-2, IL-4, IL-6, IL-10; and TNF, IFN-γ, IL-4, IL-5, IL-10, transforming growth factor-β, CXCL8, respectively. Conclusion This systematic review provides information on distinct cytokine profiles of malaria coinfections and malaria monoinfections. Further studies should investigate whether specific cytokines for each coinfection type could serve as essential diagnostic or prognostic biomarkers for malaria coinfections. Author summary Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium knowlesi infections all cause malaria, an acute febrile illness that is transmitted to people by the bites of infected female Anopheles mosquitoes. Following malaria infections in people, an individual’s ... |
format |
Article in Journal/Newspaper |
author |
Manas Kotepui Wanida Mala Pattamaporn Kwankaew Kwuntida Uthaisar Kotepui Frederick Ramirez Masangkay Polrat Wilairatana |
author_facet |
Manas Kotepui Wanida Mala Pattamaporn Kwankaew Kwuntida Uthaisar Kotepui Frederick Ramirez Masangkay Polrat Wilairatana |
author_sort |
Manas Kotepui |
title |
Distinct cytokine profiles in malaria coinfections: A systematic review |
title_short |
Distinct cytokine profiles in malaria coinfections: A systematic review |
title_full |
Distinct cytokine profiles in malaria coinfections: A systematic review |
title_fullStr |
Distinct cytokine profiles in malaria coinfections: A systematic review |
title_full_unstemmed |
Distinct cytokine profiles in malaria coinfections: A systematic review |
title_sort |
distinct cytokine profiles in malaria coinfections: a systematic review |
publisher |
Public Library of Science (PLoS) |
publishDate |
2023 |
url |
https://doaj.org/article/a57e8744a2fb462fa32b518083b3aaa5 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 17, Iss 1 (2023) |
op_relation |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886258/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 https://doaj.org/article/a57e8744a2fb462fa32b518083b3aaa5 |
_version_ |
1766344695010557952 |