An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche

An epidemic of exanthematic illness in a day care center is described. Ten children aged 7 to 13 months were affected by the illness. The exanthem was characterized by nonconfluent macular or maculopapular lesions that appeared on the face, body and limbs. Fifty percent of the infected children had...

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Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Regina C. Moreira, Silvana B. Castrignano, Rita de C. C. Carmona, Filumena M. S. Gomes, Sueli G. Saes, Rosely S Oliveira, Denise F. C. Souza, Sueko Takimoto, Marisa C. L. Costa, Eliseu Alves Waldman
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 1995
Subjects:
Online Access:https://doi.org/10.1590/S0036-46651995000300009
https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe
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spelling ftdoajarticles:oai:doaj.org/article:a4db5af9f6554a438d2f88b12bda98fe 2024-09-09T19:27:17+00:00 An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche Regina C. Moreira Silvana B. Castrignano Rita de C. C. Carmona Filumena M. S. Gomes Sueli G. Saes Rosely S Oliveira Denise F. C. Souza Sueko Takimoto Marisa C. L. Costa Eliseu Alves Waldman 1995-06-01T00:00:00Z https://doi.org/10.1590/S0036-46651995000300009 https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000300009 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651995000300009 0036-4665 1678-9946 https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe Revista do Instituto de Medicina Tropical de São Paulo, Vol 37, Iss 3, Pp 235-238 (1995) Enteroviruses Epidemiology of enterovirus Exanthematic disease Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1995 ftdoajarticles https://doi.org/10.1590/S0036-46651995000300009 2024-08-05T17:49:31Z An epidemic of exanthematic illness in a day care center is described. Ten children aged 7 to 13 months were affected by the illness. The exanthem was characterized by nonconfluent macular or maculopapular lesions that appeared on the face, body and limbs. Fifty percent of the infected children had fever of up to 39ºC at the beginning of the disease. Coxsackievirus B3 (CB3) was isolated from the stool of one ill child. Paired serum samples were obtained from eight ill children and six of them presented seroconversion to CB3. Antibodies to CB3 were detected at titers higher than 16 in a single serum sample collected from the other two patients. Neutralizing antibodies to CB3 were detected in 71.0% of the contact children. É descrita uma epidemia de doença exantemática em uma creche, acometendo 10 crianças de 7 a 13 meses de idade. O quadro exantemático caracterizou-se por lesões máculo ou maculopapulares não confluentes, que atingiam a face, tronco e pernas. 50% das crianças infectadas apresentaram febre de até 39ºC, no início da doença. Foi isolado das fezes de uma criança doente o coxsackievírus B3 (CB3). Foram examinados soros pareados de 8 das 10 crianças doentes e em 6 delas demonstrou-se soroconversão para CB3. Duas crianças que apresentaram sintomatologia e que tiveram amostras de sangue colhidas somente 7 meses após a epidemia, apresentaram anticorpos específicos contra o CB3, em títulos superiores a 16. Entre os contatos das crianças doentes, verificou-se que 71,0% do total apresentaram anticorpos neutralizantes específicos contra o CB3. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 37 3 235 238
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Enteroviruses
Epidemiology of enterovirus
Exanthematic disease
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
spellingShingle Enteroviruses
Epidemiology of enterovirus
Exanthematic disease
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Regina C. Moreira
Silvana B. Castrignano
Rita de C. C. Carmona
Filumena M. S. Gomes
Sueli G. Saes
Rosely S Oliveira
Denise F. C. Souza
Sueko Takimoto
Marisa C. L. Costa
Eliseu Alves Waldman
An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche
topic_facet Enteroviruses
Epidemiology of enterovirus
Exanthematic disease
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
description An epidemic of exanthematic illness in a day care center is described. Ten children aged 7 to 13 months were affected by the illness. The exanthem was characterized by nonconfluent macular or maculopapular lesions that appeared on the face, body and limbs. Fifty percent of the infected children had fever of up to 39ºC at the beginning of the disease. Coxsackievirus B3 (CB3) was isolated from the stool of one ill child. Paired serum samples were obtained from eight ill children and six of them presented seroconversion to CB3. Antibodies to CB3 were detected at titers higher than 16 in a single serum sample collected from the other two patients. Neutralizing antibodies to CB3 were detected in 71.0% of the contact children. É descrita uma epidemia de doença exantemática em uma creche, acometendo 10 crianças de 7 a 13 meses de idade. O quadro exantemático caracterizou-se por lesões máculo ou maculopapulares não confluentes, que atingiam a face, tronco e pernas. 50% das crianças infectadas apresentaram febre de até 39ºC, no início da doença. Foi isolado das fezes de uma criança doente o coxsackievírus B3 (CB3). Foram examinados soros pareados de 8 das 10 crianças doentes e em 6 delas demonstrou-se soroconversão para CB3. Duas crianças que apresentaram sintomatologia e que tiveram amostras de sangue colhidas somente 7 meses após a epidemia, apresentaram anticorpos específicos contra o CB3, em títulos superiores a 16. Entre os contatos das crianças doentes, verificou-se que 71,0% do total apresentaram anticorpos neutralizantes específicos contra o CB3.
format Article in Journal/Newspaper
author Regina C. Moreira
Silvana B. Castrignano
Rita de C. C. Carmona
Filumena M. S. Gomes
Sueli G. Saes
Rosely S Oliveira
Denise F. C. Souza
Sueko Takimoto
Marisa C. L. Costa
Eliseu Alves Waldman
author_facet Regina C. Moreira
Silvana B. Castrignano
Rita de C. C. Carmona
Filumena M. S. Gomes
Sueli G. Saes
Rosely S Oliveira
Denise F. C. Souza
Sueko Takimoto
Marisa C. L. Costa
Eliseu Alves Waldman
author_sort Regina C. Moreira
title An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche
title_short An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche
title_full An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche
title_fullStr An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche
title_full_unstemmed An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche
title_sort exanthematic disease epidemic associated with coxsackievirus b3 infection in a day care center epidemia de doença exantemática associada à infecção causada por coxsackievírus b3 em uma creche
publisher Universidade de São Paulo (USP)
publishDate 1995
url https://doi.org/10.1590/S0036-46651995000300009
https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe
geographic Arctic
geographic_facet Arctic
genre Arctic
genre_facet Arctic
op_source Revista do Instituto de Medicina Tropical de São Paulo, Vol 37, Iss 3, Pp 235-238 (1995)
op_relation http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000300009
https://doaj.org/toc/0036-4665
https://doaj.org/toc/1678-9946
doi:10.1590/S0036-46651995000300009
0036-4665
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op_doi https://doi.org/10.1590/S0036-46651995000300009
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