An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche
An epidemic of exanthematic illness in a day care center is described. Ten children aged 7 to 13 months were affected by the illness. The exanthem was characterized by nonconfluent macular or maculopapular lesions that appeared on the face, body and limbs. Fifty percent of the infected children had...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Language: | English |
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Universidade de São Paulo (USP)
1995
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Online Access: | https://doi.org/10.1590/S0036-46651995000300009 https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe |
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ftdoajarticles:oai:doaj.org/article:a4db5af9f6554a438d2f88b12bda98fe 2024-09-09T19:27:17+00:00 An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche Regina C. Moreira Silvana B. Castrignano Rita de C. C. Carmona Filumena M. S. Gomes Sueli G. Saes Rosely S Oliveira Denise F. C. Souza Sueko Takimoto Marisa C. L. Costa Eliseu Alves Waldman 1995-06-01T00:00:00Z https://doi.org/10.1590/S0036-46651995000300009 https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe EN eng Universidade de São Paulo (USP) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000300009 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651995000300009 0036-4665 1678-9946 https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe Revista do Instituto de Medicina Tropical de São Paulo, Vol 37, Iss 3, Pp 235-238 (1995) Enteroviruses Epidemiology of enterovirus Exanthematic disease Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 1995 ftdoajarticles https://doi.org/10.1590/S0036-46651995000300009 2024-08-05T17:49:31Z An epidemic of exanthematic illness in a day care center is described. Ten children aged 7 to 13 months were affected by the illness. The exanthem was characterized by nonconfluent macular or maculopapular lesions that appeared on the face, body and limbs. Fifty percent of the infected children had fever of up to 39ºC at the beginning of the disease. Coxsackievirus B3 (CB3) was isolated from the stool of one ill child. Paired serum samples were obtained from eight ill children and six of them presented seroconversion to CB3. Antibodies to CB3 were detected at titers higher than 16 in a single serum sample collected from the other two patients. Neutralizing antibodies to CB3 were detected in 71.0% of the contact children. É descrita uma epidemia de doença exantemática em uma creche, acometendo 10 crianças de 7 a 13 meses de idade. O quadro exantemático caracterizou-se por lesões máculo ou maculopapulares não confluentes, que atingiam a face, tronco e pernas. 50% das crianças infectadas apresentaram febre de até 39ºC, no início da doença. Foi isolado das fezes de uma criança doente o coxsackievírus B3 (CB3). Foram examinados soros pareados de 8 das 10 crianças doentes e em 6 delas demonstrou-se soroconversão para CB3. Duas crianças que apresentaram sintomatologia e que tiveram amostras de sangue colhidas somente 7 meses após a epidemia, apresentaram anticorpos específicos contra o CB3, em títulos superiores a 16. Entre os contatos das crianças doentes, verificou-se que 71,0% do total apresentaram anticorpos neutralizantes específicos contra o CB3. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista do Instituto de Medicina Tropical de São Paulo 37 3 235 238 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Enteroviruses Epidemiology of enterovirus Exanthematic disease Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Enteroviruses Epidemiology of enterovirus Exanthematic disease Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Regina C. Moreira Silvana B. Castrignano Rita de C. C. Carmona Filumena M. S. Gomes Sueli G. Saes Rosely S Oliveira Denise F. C. Souza Sueko Takimoto Marisa C. L. Costa Eliseu Alves Waldman An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche |
topic_facet |
Enteroviruses Epidemiology of enterovirus Exanthematic disease Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
An epidemic of exanthematic illness in a day care center is described. Ten children aged 7 to 13 months were affected by the illness. The exanthem was characterized by nonconfluent macular or maculopapular lesions that appeared on the face, body and limbs. Fifty percent of the infected children had fever of up to 39ºC at the beginning of the disease. Coxsackievirus B3 (CB3) was isolated from the stool of one ill child. Paired serum samples were obtained from eight ill children and six of them presented seroconversion to CB3. Antibodies to CB3 were detected at titers higher than 16 in a single serum sample collected from the other two patients. Neutralizing antibodies to CB3 were detected in 71.0% of the contact children. É descrita uma epidemia de doença exantemática em uma creche, acometendo 10 crianças de 7 a 13 meses de idade. O quadro exantemático caracterizou-se por lesões máculo ou maculopapulares não confluentes, que atingiam a face, tronco e pernas. 50% das crianças infectadas apresentaram febre de até 39ºC, no início da doença. Foi isolado das fezes de uma criança doente o coxsackievírus B3 (CB3). Foram examinados soros pareados de 8 das 10 crianças doentes e em 6 delas demonstrou-se soroconversão para CB3. Duas crianças que apresentaram sintomatologia e que tiveram amostras de sangue colhidas somente 7 meses após a epidemia, apresentaram anticorpos específicos contra o CB3, em títulos superiores a 16. Entre os contatos das crianças doentes, verificou-se que 71,0% do total apresentaram anticorpos neutralizantes específicos contra o CB3. |
format |
Article in Journal/Newspaper |
author |
Regina C. Moreira Silvana B. Castrignano Rita de C. C. Carmona Filumena M. S. Gomes Sueli G. Saes Rosely S Oliveira Denise F. C. Souza Sueko Takimoto Marisa C. L. Costa Eliseu Alves Waldman |
author_facet |
Regina C. Moreira Silvana B. Castrignano Rita de C. C. Carmona Filumena M. S. Gomes Sueli G. Saes Rosely S Oliveira Denise F. C. Souza Sueko Takimoto Marisa C. L. Costa Eliseu Alves Waldman |
author_sort |
Regina C. Moreira |
title |
An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche |
title_short |
An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche |
title_full |
An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche |
title_fullStr |
An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche |
title_full_unstemmed |
An exanthematic disease epidemic associated with coxsackievirus B3 infection in a day care center Epidemia de doença exantemática associada à infecção causada por coxsackievírus B3 em uma creche |
title_sort |
exanthematic disease epidemic associated with coxsackievirus b3 infection in a day care center epidemia de doença exantemática associada à infecção causada por coxsackievírus b3 em uma creche |
publisher |
Universidade de São Paulo (USP) |
publishDate |
1995 |
url |
https://doi.org/10.1590/S0036-46651995000300009 https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 37, Iss 3, Pp 235-238 (1995) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651995000300009 https://doaj.org/toc/0036-4665 https://doaj.org/toc/1678-9946 doi:10.1590/S0036-46651995000300009 0036-4665 1678-9946 https://doaj.org/article/a4db5af9f6554a438d2f88b12bda98fe |
op_doi |
https://doi.org/10.1590/S0036-46651995000300009 |
container_title |
Revista do Instituto de Medicina Tropical de São Paulo |
container_volume |
37 |
container_issue |
3 |
container_start_page |
235 |
op_container_end_page |
238 |
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