Schistosome migration in the definitive host.
Schistosomes are parasitic blood flukes that infect >200 million people around the world. Free-swimming larval stages penetrate the skin, invade a blood vessel, and migrate through the heart and lungs to the vasculature of the liver, where maturation and mating occurs. From here, the parasite cou...
Published in: | PLOS Neglected Tropical Diseases |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020
|
Subjects: | |
Online Access: | https://doi.org/10.1371/journal.pntd.0007951 https://doaj.org/article/a425b3d81434489f9f837b3e2bc24db7 |
id |
ftdoajarticles:oai:doaj.org/article:a425b3d81434489f9f837b3e2bc24db7 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:a425b3d81434489f9f837b3e2bc24db7 2023-05-15T15:03:58+02:00 Schistosome migration in the definitive host. Catherine S Nation Akram A Da'dara Jeffrey K Marchant Patrick J Skelly 2020-04-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0007951 https://doaj.org/article/a425b3d81434489f9f837b3e2bc24db7 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0007951 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007951 https://doaj.org/article/a425b3d81434489f9f837b3e2bc24db7 PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0007951 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0007951 2022-12-31T11:50:15Z Schistosomes are parasitic blood flukes that infect >200 million people around the world. Free-swimming larval stages penetrate the skin, invade a blood vessel, and migrate through the heart and lungs to the vasculature of the liver, where maturation and mating occurs. From here, the parasite couples migrate to their preferred egg laying sites. Here, we compare and contrast what is known about the migration patterns within the definitive host of the three major species of human schistosome: Schistosoma mansoni, S. japonicum, and S. haematobium. We conclude that intravascular schistosomes are inexorable colonizers whose migration and egg laying strategy is profligate; all three species (and their eggs) can be found throughout the mesenteric venules, the rectal venous plexus, and, to a greater or lesser extent, the urogenital venous plexuses. In addition, it is common for parasite eggs to be deposited in locations that lack easy access to the exterior, further demonstrating the relentless exploratory nature of these intravascular worms. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 4 e0007951 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Catherine S Nation Akram A Da'dara Jeffrey K Marchant Patrick J Skelly Schistosome migration in the definitive host. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Schistosomes are parasitic blood flukes that infect >200 million people around the world. Free-swimming larval stages penetrate the skin, invade a blood vessel, and migrate through the heart and lungs to the vasculature of the liver, where maturation and mating occurs. From here, the parasite couples migrate to their preferred egg laying sites. Here, we compare and contrast what is known about the migration patterns within the definitive host of the three major species of human schistosome: Schistosoma mansoni, S. japonicum, and S. haematobium. We conclude that intravascular schistosomes are inexorable colonizers whose migration and egg laying strategy is profligate; all three species (and their eggs) can be found throughout the mesenteric venules, the rectal venous plexus, and, to a greater or lesser extent, the urogenital venous plexuses. In addition, it is common for parasite eggs to be deposited in locations that lack easy access to the exterior, further demonstrating the relentless exploratory nature of these intravascular worms. |
format |
Article in Journal/Newspaper |
author |
Catherine S Nation Akram A Da'dara Jeffrey K Marchant Patrick J Skelly |
author_facet |
Catherine S Nation Akram A Da'dara Jeffrey K Marchant Patrick J Skelly |
author_sort |
Catherine S Nation |
title |
Schistosome migration in the definitive host. |
title_short |
Schistosome migration in the definitive host. |
title_full |
Schistosome migration in the definitive host. |
title_fullStr |
Schistosome migration in the definitive host. |
title_full_unstemmed |
Schistosome migration in the definitive host. |
title_sort |
schistosome migration in the definitive host. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0007951 https://doaj.org/article/a425b3d81434489f9f837b3e2bc24db7 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0007951 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0007951 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007951 https://doaj.org/article/a425b3d81434489f9f837b3e2bc24db7 |
op_doi |
https://doi.org/10.1371/journal.pntd.0007951 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
14 |
container_issue |
4 |
container_start_page |
e0007951 |
_version_ |
1766335804000436224 |