Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference.

• Published in: PLoS Neglected Tropical Diseases
• Main Authors: M M Mourão, Nathalie Dinguirard, Glória R Franco, Timothy P Yoshino
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2009
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; K5
• Online Access: https://doi.org/10.1371/journal.pntd.0000502; https://doaj.org/article/a3df925920ff4695bf20f726db48a01c

RNA interference (RNAi) represents the only method currently available for manipulating gene-specific expression in Schistosoma spp., although application of this technology as a functional genomic profiling tool has yet to be explored. In the present study 32 genes, including antioxidants, transcri...