Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso
Abstract The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported. Of 28 children treated with a standard single dose of pyrimethamine-sulfadoxine and followed-up over 14 days, onl...
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ftdoajarticles:oai:doaj.org/article:a395e25c8fc34a03acd97825b8694195 2023-05-15T15:01:35+02:00 Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso Traore Corneille Müller Olaf Kouyate Bocar 2004-05-01T00:00:00Z https://doi.org/10.1186/1475-2875-3-10 https://doaj.org/article/a395e25c8fc34a03acd97825b8694195 EN eng BMC http://www.malariajournal.com/content/3/1/10 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-3-10 1475-2875 https://doaj.org/article/a395e25c8fc34a03acd97825b8694195 Malaria Journal, Vol 3, Iss 1, p 10 (2004) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2004 ftdoajarticles https://doi.org/10.1186/1475-2875-3-10 2022-12-31T08:22:06Z Abstract The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported. Of 28 children treated with a standard single dose of pyrimethamine-sulfadoxine and followed-up over 14 days, only one Late Treatment Failure and four Late Parasitological Failures were observed, all with low-grade parasitaemia. In this area of very restricted use of pyrimethamine-sulfadoxine, the drug appears to be still sufficiently effective in the treatment of malaria. These findings provide further evidence for the justification of continued use of pyrimethamine-sulfadoxine as a second-line treatment for malaria in Burkina Faso. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 3 1 10 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Traore Corneille Müller Olaf Kouyate Bocar Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported. Of 28 children treated with a standard single dose of pyrimethamine-sulfadoxine and followed-up over 14 days, only one Late Treatment Failure and four Late Parasitological Failures were observed, all with low-grade parasitaemia. In this area of very restricted use of pyrimethamine-sulfadoxine, the drug appears to be still sufficiently effective in the treatment of malaria. These findings provide further evidence for the justification of continued use of pyrimethamine-sulfadoxine as a second-line treatment for malaria in Burkina Faso. |
format |
Article in Journal/Newspaper |
author |
Traore Corneille Müller Olaf Kouyate Bocar |
author_facet |
Traore Corneille Müller Olaf Kouyate Bocar |
author_sort |
Traore Corneille |
title |
Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso |
title_short |
Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso |
title_full |
Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso |
title_fullStr |
Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso |
title_full_unstemmed |
Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso |
title_sort |
efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural burkina faso |
publisher |
BMC |
publishDate |
2004 |
url |
https://doi.org/10.1186/1475-2875-3-10 https://doaj.org/article/a395e25c8fc34a03acd97825b8694195 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 3, Iss 1, p 10 (2004) |
op_relation |
http://www.malariajournal.com/content/3/1/10 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-3-10 1475-2875 https://doaj.org/article/a395e25c8fc34a03acd97825b8694195 |
op_doi |
https://doi.org/10.1186/1475-2875-3-10 |
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Malaria Journal |
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3 |
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1 |
container_start_page |
10 |
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1766333595632271360 |