Japanese encephalitis-a pathological and clinical perspective.
Japanese encephalitis (JE) is the leading form of viral encephalitis in Asia. It is caused by the JE virus (JEV), which belongs to the family Flaviviridae. JEV is endemic to many parts of Asia, where periodic outbreaks take hundreds of lives. Despite the catastrophes it causes, JE has remained a tro...
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ftdoajarticles:oai:doaj.org/article:a34fe68830824a90ab2c9bb4e03d1f20 2023-05-15T15:05:18+02:00 Japanese encephalitis-a pathological and clinical perspective. Debapriya Ghosh Anirban Basu 2009-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0000437 https://doaj.org/article/a34fe68830824a90ab2c9bb4e03d1f20 EN eng Public Library of Science (PLoS) https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19787040/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0000437 https://doaj.org/article/a34fe68830824a90ab2c9bb4e03d1f20 PLoS Neglected Tropical Diseases, Vol 3, Iss 9, p e437 (2009) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2009 ftdoajarticles https://doi.org/10.1371/journal.pntd.0000437 2022-12-31T05:05:11Z Japanese encephalitis (JE) is the leading form of viral encephalitis in Asia. It is caused by the JE virus (JEV), which belongs to the family Flaviviridae. JEV is endemic to many parts of Asia, where periodic outbreaks take hundreds of lives. Despite the catastrophes it causes, JE has remained a tropical disease uncommon in the West. With rapid globalization and climatic shift, JEV has started to emerge in areas where the threat was previously unknown. Scientific evidence predicts that JEV will soon become a global pathogen and cause of worldwide pandemics. Although some research documents JEV pathogenesis and drug discovery, worldwide awareness of the need for extensive research to deal with JE is still lacking. This review focuses on the exigency of developing a worldwide effort to acknowledge the prime importance of performing an extensive study of this thus far neglected tropical viral disease. This review also outlines the pathogenesis, the scientific efforts channeled into develop a therapy, and the outlook for a possible future breakthrough addressing this killer disease. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 3 9 e437 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Debapriya Ghosh Anirban Basu Japanese encephalitis-a pathological and clinical perspective. |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Japanese encephalitis (JE) is the leading form of viral encephalitis in Asia. It is caused by the JE virus (JEV), which belongs to the family Flaviviridae. JEV is endemic to many parts of Asia, where periodic outbreaks take hundreds of lives. Despite the catastrophes it causes, JE has remained a tropical disease uncommon in the West. With rapid globalization and climatic shift, JEV has started to emerge in areas where the threat was previously unknown. Scientific evidence predicts that JEV will soon become a global pathogen and cause of worldwide pandemics. Although some research documents JEV pathogenesis and drug discovery, worldwide awareness of the need for extensive research to deal with JE is still lacking. This review focuses on the exigency of developing a worldwide effort to acknowledge the prime importance of performing an extensive study of this thus far neglected tropical viral disease. This review also outlines the pathogenesis, the scientific efforts channeled into develop a therapy, and the outlook for a possible future breakthrough addressing this killer disease. |
format |
Article in Journal/Newspaper |
author |
Debapriya Ghosh Anirban Basu |
author_facet |
Debapriya Ghosh Anirban Basu |
author_sort |
Debapriya Ghosh |
title |
Japanese encephalitis-a pathological and clinical perspective. |
title_short |
Japanese encephalitis-a pathological and clinical perspective. |
title_full |
Japanese encephalitis-a pathological and clinical perspective. |
title_fullStr |
Japanese encephalitis-a pathological and clinical perspective. |
title_full_unstemmed |
Japanese encephalitis-a pathological and clinical perspective. |
title_sort |
japanese encephalitis-a pathological and clinical perspective. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2009 |
url |
https://doi.org/10.1371/journal.pntd.0000437 https://doaj.org/article/a34fe68830824a90ab2c9bb4e03d1f20 |
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Arctic |
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Arctic |
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Arctic |
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Arctic |
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PLoS Neglected Tropical Diseases, Vol 3, Iss 9, p e437 (2009) |
op_relation |
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19787040/?tool=EBI https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0000437 https://doaj.org/article/a34fe68830824a90ab2c9bb4e03d1f20 |
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https://doi.org/10.1371/journal.pntd.0000437 |
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e437 |
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