Copeptin does not accurately predict disease severity in imported malaria

• Published in: Malaria Journal
• Main Authors: van Wolfswinkel Marlies E, Hesselink Dennis A, Hoorn Ewout J, de Rijke Yolanda B, Koelewijn Rob, van Hellemond Jaap J, van Genderen Perry JJ
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2012
• Subjects: Malaria; Imported; Severity; Biomarkers; Copeptin; Arginine vasopressin; C-reactive protein; CRP; Traveller; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1186/1475-2875-11-6; https://doaj.org/article/a3449e63909f4119b7ba310e90db916d

Abstract Background Copeptin has recently been identified to be a stable surrogate marker for the unstable hormone arginine vasopressin (AVP). Copeptin has been shown to correlate with disease severity in leptospirosis and bacterial sepsis. Hyponatraemia is common in severe imported malaria and dysr...