What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis
Abstract Background Reactive malaria case detection involves the screening of those in contact with index cases and is used in countries in the Greater Mekong Sub-region. The yield of reactive case detection, defined here as the percentage of positive malaria cases among potential contacts who were...
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ftdoajarticles:oai:doaj.org/article:a29557dde5de45f0ab81dc29a743c001 2023-05-15T15:11:14+02:00 What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis Jacqueline Deen Mavuto Mukaka Lorenz von Seidlein 2021-03-01T00:00:00Z https://doi.org/10.1186/s12936-021-03667-5 https://doaj.org/article/a29557dde5de45f0ab81dc29a743c001 EN eng BMC https://doi.org/10.1186/s12936-021-03667-5 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-021-03667-5 1475-2875 https://doaj.org/article/a29557dde5de45f0ab81dc29a743c001 Malaria Journal, Vol 20, Iss 1, Pp 1-8 (2021) Malaria Active case detection Reactive case detection Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2021 ftdoajarticles https://doi.org/10.1186/s12936-021-03667-5 2022-12-31T06:17:09Z Abstract Background Reactive malaria case detection involves the screening of those in contact with index cases and is used in countries in the Greater Mekong Sub-region. The yield of reactive case detection, defined here as the percentage of positive malaria cases among potential contacts who were screened, was assessed. Methods A literature search was conducted on PubMed to identify studies on reactive case detection in the Greater Mekong Sub-region. Eligible published articles were reviewed and pooled estimates from the studies were calculated, by type of malaria test used. Results Eighty-five publications were retrieved, of which 8 (9.4%) eligible articles were included in the analysis. The yield from reactive case detection ranged from 0.1 to 4.2%, with higher rates from PCR testing compared with microscopy and/or rapid diagnostic test. The overall yield from microscopy and/or rapid diagnostic test was 0.56% (95% CI 0.31–0.88%), while that from PCR was 2.35% (95% CI 1.19–3.87%). The two studies comparing different target groups showed higher yield from co-workers/co-travellers, compared with household contacts. Conclusion In low malaria transmission settings, the effectiveness of reactive case detection is diminishing. In the Greater Mekong Sub-region, modifying reactive case detection from household contacts to co-workers/co-travellers and from testing to presumptive treatment of targeted contacts, could increase the impact of this approach. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 20 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Malaria Active case detection Reactive case detection Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Malaria Active case detection Reactive case detection Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Jacqueline Deen Mavuto Mukaka Lorenz von Seidlein What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis |
topic_facet |
Malaria Active case detection Reactive case detection Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Reactive malaria case detection involves the screening of those in contact with index cases and is used in countries in the Greater Mekong Sub-region. The yield of reactive case detection, defined here as the percentage of positive malaria cases among potential contacts who were screened, was assessed. Methods A literature search was conducted on PubMed to identify studies on reactive case detection in the Greater Mekong Sub-region. Eligible published articles were reviewed and pooled estimates from the studies were calculated, by type of malaria test used. Results Eighty-five publications were retrieved, of which 8 (9.4%) eligible articles were included in the analysis. The yield from reactive case detection ranged from 0.1 to 4.2%, with higher rates from PCR testing compared with microscopy and/or rapid diagnostic test. The overall yield from microscopy and/or rapid diagnostic test was 0.56% (95% CI 0.31–0.88%), while that from PCR was 2.35% (95% CI 1.19–3.87%). The two studies comparing different target groups showed higher yield from co-workers/co-travellers, compared with household contacts. Conclusion In low malaria transmission settings, the effectiveness of reactive case detection is diminishing. In the Greater Mekong Sub-region, modifying reactive case detection from household contacts to co-workers/co-travellers and from testing to presumptive treatment of targeted contacts, could increase the impact of this approach. |
format |
Article in Journal/Newspaper |
author |
Jacqueline Deen Mavuto Mukaka Lorenz von Seidlein |
author_facet |
Jacqueline Deen Mavuto Mukaka Lorenz von Seidlein |
author_sort |
Jacqueline Deen |
title |
What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis |
title_short |
What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis |
title_full |
What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis |
title_fullStr |
What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis |
title_full_unstemmed |
What is the yield of malaria reactive case detection in the Greater Mekong Sub-region? A review of published data and meta-analysis |
title_sort |
what is the yield of malaria reactive case detection in the greater mekong sub-region? a review of published data and meta-analysis |
publisher |
BMC |
publishDate |
2021 |
url |
https://doi.org/10.1186/s12936-021-03667-5 https://doaj.org/article/a29557dde5de45f0ab81dc29a743c001 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 20, Iss 1, Pp 1-8 (2021) |
op_relation |
https://doi.org/10.1186/s12936-021-03667-5 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-021-03667-5 1475-2875 https://doaj.org/article/a29557dde5de45f0ab81dc29a743c001 |
op_doi |
https://doi.org/10.1186/s12936-021-03667-5 |
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Malaria Journal |
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20 |
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1 |
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1766342124766232576 |