Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings.
The Ebola virus disease (EVD) outbreak in West Africa was unprecedented in scale and location. Limited access to both diagnostic and supportive pathology assays in both resource-rich and resource-limited settings had a detrimental effect on the identification and isolation of cases as well as indivi...
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ftdoajarticles:oai:doaj.org/article:a233a6dcf3e14349b32e5b7d4eac814e 2023-05-15T15:02:48+02:00 Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings. Robert J Shorten Colin S Brown Michael Jacobs Simon Rattenbury Andrew J Simpson Stephen Mepham 2016-10-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004948 https://doaj.org/article/a233a6dcf3e14349b32e5b7d4eac814e EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5082928?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004948 https://doaj.org/article/a233a6dcf3e14349b32e5b7d4eac814e PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0004948 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004948 2022-12-31T14:10:45Z The Ebola virus disease (EVD) outbreak in West Africa was unprecedented in scale and location. Limited access to both diagnostic and supportive pathology assays in both resource-rich and resource-limited settings had a detrimental effect on the identification and isolation of cases as well as individual patient management. Limited access to such assays in resource-rich settings resulted in delays in differentiating EVD from other illnesses in returning travellers, in turn utilising valuable resources until a diagnosis could be made. This had a much greater impact in West Africa, where it contributed to the initial failure to contain the outbreak. This review explores diagnostic assays of use in EVD in both resource-rich and resource-limited settings, including their respective limitations, and some novel assays and approaches that may be of use in future outbreaks. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 10 e0004948 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Robert J Shorten Colin S Brown Michael Jacobs Simon Rattenbury Andrew J Simpson Stephen Mepham Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
The Ebola virus disease (EVD) outbreak in West Africa was unprecedented in scale and location. Limited access to both diagnostic and supportive pathology assays in both resource-rich and resource-limited settings had a detrimental effect on the identification and isolation of cases as well as individual patient management. Limited access to such assays in resource-rich settings resulted in delays in differentiating EVD from other illnesses in returning travellers, in turn utilising valuable resources until a diagnosis could be made. This had a much greater impact in West Africa, where it contributed to the initial failure to contain the outbreak. This review explores diagnostic assays of use in EVD in both resource-rich and resource-limited settings, including their respective limitations, and some novel assays and approaches that may be of use in future outbreaks. |
format |
Article in Journal/Newspaper |
author |
Robert J Shorten Colin S Brown Michael Jacobs Simon Rattenbury Andrew J Simpson Stephen Mepham |
author_facet |
Robert J Shorten Colin S Brown Michael Jacobs Simon Rattenbury Andrew J Simpson Stephen Mepham |
author_sort |
Robert J Shorten |
title |
Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings. |
title_short |
Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings. |
title_full |
Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings. |
title_fullStr |
Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings. |
title_full_unstemmed |
Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings. |
title_sort |
diagnostics in ebola virus disease in resource-rich and resource-limited settings. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0004948 https://doaj.org/article/a233a6dcf3e14349b32e5b7d4eac814e |
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Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
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PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0004948 (2016) |
op_relation |
http://europepmc.org/articles/PMC5082928?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004948 https://doaj.org/article/a233a6dcf3e14349b32e5b7d4eac814e |
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https://doi.org/10.1371/journal.pntd.0004948 |
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PLOS Neglected Tropical Diseases |
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10 |
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e0004948 |
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