A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania
Abstract Background Despite the development of resistance to Plasmodium falciparum malaria, sulfadoxine–pyrimethamine is still effective for intermittent preventive treatment of malaria in pregnancy (IPTp). In Tanzania, more than 10 years have passed since sulfadoxine–pyrimethamine and sulfamethopyr...
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ftdoajarticles:oai:doaj.org/article:a218fda8b9d94388b44d3bda86964923 2023-05-15T15:16:46+02:00 A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania Alphonce I. Marealle Dennis P. Mbwambo Wigilya P. Mikomangwa Manase Kilonzi Hamu J. Mlyuka Ritah F. Mutagonda 2018-11-01T00:00:00Z https://doi.org/10.1186/s12936-018-2565-1 https://doaj.org/article/a218fda8b9d94388b44d3bda86964923 EN eng BMC http://link.springer.com/article/10.1186/s12936-018-2565-1 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-018-2565-1 1475-2875 https://doaj.org/article/a218fda8b9d94388b44d3bda86964923 Malaria Journal, Vol 17, Iss 1, Pp 1-7 (2018) Sulfonamide-based antimalarials Availability Medicine dispensers Knowledge Practice Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2018 ftdoajarticles https://doi.org/10.1186/s12936-018-2565-1 2022-12-31T14:44:25Z Abstract Background Despite the development of resistance to Plasmodium falciparum malaria, sulfadoxine–pyrimethamine is still effective for intermittent preventive treatment of malaria in pregnancy (IPTp). In Tanzania, more than 10 years have passed since sulfadoxine–pyrimethamine and sulfamethopyrazine–pyrimethamine (SPs) were reserved for IPTp only. However, the retail pharmaceutical outlet dispensers’ knowledge and their compliance with the policies have not been recently explored. Therefore, this study was designed to investigate dispensers’ knowledge about these medications together with their actual dispensing practices, a decade since they were limited for IPTp use only. Methods This descriptive cross-sectional study was conducted between February and July 2017 in all municipalities of Dar-es-Salaam city. Data were collected by direct interviews using a structured questionnaire to assess knowledge and a simulated client approach was used to assess the actual practice of medicine dispensers. Data analysis was done by using SPSS version 20 and Chi square test was used to test significant differences in proportions between different categorical variables. A p-value of less than 0.05 was considered to be statistically significant. Results A random sample of 422 medicine dispensers participated in this study whereby 185 (43.8%) were from community pharmacies and 237 (56.2%) from accredited drug dispensing outlets. The study revealed that SPs were available in 76% of the community pharmaceutical outlets in Dar es Salaam. In general majority of the dispensers (64%) had moderate to high knowledge about SPs and their indication. About 80% of the dispensers were aware that SP is reserved for IPTp. However, irrespective of the level of knowledge, almost all dispensers (92%) were willing to dispense the medicines for the purpose of treating malaria, contrary to the current Tanzania malaria treatment guideline. Conclusion Majority of the medicine dispensers in the community pharmaceutical outlets were knowledgeable ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 17 1 |
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Sulfonamide-based antimalarials Availability Medicine dispensers Knowledge Practice Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Sulfonamide-based antimalarials Availability Medicine dispensers Knowledge Practice Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Alphonce I. Marealle Dennis P. Mbwambo Wigilya P. Mikomangwa Manase Kilonzi Hamu J. Mlyuka Ritah F. Mutagonda A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania |
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Sulfonamide-based antimalarials Availability Medicine dispensers Knowledge Practice Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Despite the development of resistance to Plasmodium falciparum malaria, sulfadoxine–pyrimethamine is still effective for intermittent preventive treatment of malaria in pregnancy (IPTp). In Tanzania, more than 10 years have passed since sulfadoxine–pyrimethamine and sulfamethopyrazine–pyrimethamine (SPs) were reserved for IPTp only. However, the retail pharmaceutical outlet dispensers’ knowledge and their compliance with the policies have not been recently explored. Therefore, this study was designed to investigate dispensers’ knowledge about these medications together with their actual dispensing practices, a decade since they were limited for IPTp use only. Methods This descriptive cross-sectional study was conducted between February and July 2017 in all municipalities of Dar-es-Salaam city. Data were collected by direct interviews using a structured questionnaire to assess knowledge and a simulated client approach was used to assess the actual practice of medicine dispensers. Data analysis was done by using SPSS version 20 and Chi square test was used to test significant differences in proportions between different categorical variables. A p-value of less than 0.05 was considered to be statistically significant. Results A random sample of 422 medicine dispensers participated in this study whereby 185 (43.8%) were from community pharmacies and 237 (56.2%) from accredited drug dispensing outlets. The study revealed that SPs were available in 76% of the community pharmaceutical outlets in Dar es Salaam. In general majority of the dispensers (64%) had moderate to high knowledge about SPs and their indication. About 80% of the dispensers were aware that SP is reserved for IPTp. However, irrespective of the level of knowledge, almost all dispensers (92%) were willing to dispense the medicines for the purpose of treating malaria, contrary to the current Tanzania malaria treatment guideline. Conclusion Majority of the medicine dispensers in the community pharmaceutical outlets were knowledgeable ... |
format |
Article in Journal/Newspaper |
author |
Alphonce I. Marealle Dennis P. Mbwambo Wigilya P. Mikomangwa Manase Kilonzi Hamu J. Mlyuka Ritah F. Mutagonda |
author_facet |
Alphonce I. Marealle Dennis P. Mbwambo Wigilya P. Mikomangwa Manase Kilonzi Hamu J. Mlyuka Ritah F. Mutagonda |
author_sort |
Alphonce I. Marealle |
title |
A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania |
title_short |
A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania |
title_full |
A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania |
title_fullStr |
A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania |
title_full_unstemmed |
A decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in Tanzania |
title_sort |
decade since sulfonamide-based anti-malarial medicines were limited for intermittent preventive treatment of malaria among pregnant women in tanzania |
publisher |
BMC |
publishDate |
2018 |
url |
https://doi.org/10.1186/s12936-018-2565-1 https://doaj.org/article/a218fda8b9d94388b44d3bda86964923 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 17, Iss 1, Pp 1-7 (2018) |
op_relation |
http://link.springer.com/article/10.1186/s12936-018-2565-1 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-018-2565-1 1475-2875 https://doaj.org/article/a218fda8b9d94388b44d3bda86964923 |
op_doi |
https://doi.org/10.1186/s12936-018-2565-1 |
container_title |
Malaria Journal |
container_volume |
17 |
container_issue |
1 |
_version_ |
1766347053112229888 |