Frequency of the Risk A Allele of rs17713054 Localized in the 3p21.31 COVID-19 Risk Locus in the Yakut Population
Background: Genome-wide association studies identified the region of chromosome 3p21.31 as having the strongest association with the severe COVID-19 and susceptibility to SARS-CoV-2 infection. The aim of our study was to investigate the frequency of the risk A allele of rs17713054 localized in the 3...
Published in: | International Journal of Biomedicine |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
International Medical Research and Development Corporation
2022
|
Subjects: | |
Online Access: | https://doi.org/10.21103/Article12(1)_OA19 https://doaj.org/article/a1ed268956904b228a31c1a49391d3c3 |
id |
ftdoajarticles:oai:doaj.org/article:a1ed268956904b228a31c1a49391d3c3 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:a1ed268956904b228a31c1a49391d3c3 2023-05-15T18:45:15+02:00 Frequency of the Risk A Allele of rs17713054 Localized in the 3p21.31 COVID-19 Risk Locus in the Yakut Population Nadezhda I. Pavlova Aleksey A. Bochurov Vladislav A. Alekseev Aleksandra T. Diakonova Vladimir V. Dodokhov Khariton A. Kurtanov 2022-03-01T00:00:00Z https://doi.org/10.21103/Article12(1)_OA19 https://doaj.org/article/a1ed268956904b228a31c1a49391d3c3 EN eng International Medical Research and Development Corporation http://www.ijbm.org/articles/i45/ijbm_12(1)_oa19.pdf https://doaj.org/toc/2158-0510 https://doaj.org/toc/2158-0529 doi:10.21103/Article12(1)_OA19 2158-0510 2158-0529 https://doaj.org/article/a1ed268956904b228a31c1a49391d3c3 International Journal of Biomedicine, Vol 12, Iss 1, Pp 155-159 (2022) sars-cov-2 rs17713054 epithelial-mesenchymal transition leucine zipper transcription factor like 1 Medicine R article 2022 ftdoajarticles https://doi.org/10.21103/Article12(1)_OA19 2022-12-31T12:59:21Z Background: Genome-wide association studies identified the region of chromosome 3p21.31 as having the strongest association with the severe COVID-19 and susceptibility to SARS-CoV-2 infection. The aim of our study was to investigate the frequency of the risk A allele of rs17713054 localized in the 3p21.31 COVID-19 risk locus in Yakuts. Methods and Results: A total of 382 DNA samples from healthy Yakut volunteers (184 men and 198 women; the average age of 41.8±0.05 years) were examined. Our results show that the frequency of the risk A allele of the rs17713054 SNP in the Yakut population occurs at a frequency of 2% and generally corresponds to the frequency of East Asian populations (from 0% to 2%), geographically close to the Yakuts and belonging to the same Mongoloid race. Article in Journal/Newspaper Yakuts Directory of Open Access Journals: DOAJ Articles International Journal of Biomedicine 12 1 155 159 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
sars-cov-2 rs17713054 epithelial-mesenchymal transition leucine zipper transcription factor like 1 Medicine R |
spellingShingle |
sars-cov-2 rs17713054 epithelial-mesenchymal transition leucine zipper transcription factor like 1 Medicine R Nadezhda I. Pavlova Aleksey A. Bochurov Vladislav A. Alekseev Aleksandra T. Diakonova Vladimir V. Dodokhov Khariton A. Kurtanov Frequency of the Risk A Allele of rs17713054 Localized in the 3p21.31 COVID-19 Risk Locus in the Yakut Population |
topic_facet |
sars-cov-2 rs17713054 epithelial-mesenchymal transition leucine zipper transcription factor like 1 Medicine R |
description |
Background: Genome-wide association studies identified the region of chromosome 3p21.31 as having the strongest association with the severe COVID-19 and susceptibility to SARS-CoV-2 infection. The aim of our study was to investigate the frequency of the risk A allele of rs17713054 localized in the 3p21.31 COVID-19 risk locus in Yakuts. Methods and Results: A total of 382 DNA samples from healthy Yakut volunteers (184 men and 198 women; the average age of 41.8±0.05 years) were examined. Our results show that the frequency of the risk A allele of the rs17713054 SNP in the Yakut population occurs at a frequency of 2% and generally corresponds to the frequency of East Asian populations (from 0% to 2%), geographically close to the Yakuts and belonging to the same Mongoloid race. |
format |
Article in Journal/Newspaper |
author |
Nadezhda I. Pavlova Aleksey A. Bochurov Vladislav A. Alekseev Aleksandra T. Diakonova Vladimir V. Dodokhov Khariton A. Kurtanov |
author_facet |
Nadezhda I. Pavlova Aleksey A. Bochurov Vladislav A. Alekseev Aleksandra T. Diakonova Vladimir V. Dodokhov Khariton A. Kurtanov |
author_sort |
Nadezhda I. Pavlova |
title |
Frequency of the Risk A Allele of rs17713054 Localized in the 3p21.31 COVID-19 Risk Locus in the Yakut Population |
title_short |
Frequency of the Risk A Allele of rs17713054 Localized in the 3p21.31 COVID-19 Risk Locus in the Yakut Population |
title_full |
Frequency of the Risk A Allele of rs17713054 Localized in the 3p21.31 COVID-19 Risk Locus in the Yakut Population |
title_fullStr |
Frequency of the Risk A Allele of rs17713054 Localized in the 3p21.31 COVID-19 Risk Locus in the Yakut Population |
title_full_unstemmed |
Frequency of the Risk A Allele of rs17713054 Localized in the 3p21.31 COVID-19 Risk Locus in the Yakut Population |
title_sort |
frequency of the risk a allele of rs17713054 localized in the 3p21.31 covid-19 risk locus in the yakut population |
publisher |
International Medical Research and Development Corporation |
publishDate |
2022 |
url |
https://doi.org/10.21103/Article12(1)_OA19 https://doaj.org/article/a1ed268956904b228a31c1a49391d3c3 |
genre |
Yakuts |
genre_facet |
Yakuts |
op_source |
International Journal of Biomedicine, Vol 12, Iss 1, Pp 155-159 (2022) |
op_relation |
http://www.ijbm.org/articles/i45/ijbm_12(1)_oa19.pdf https://doaj.org/toc/2158-0510 https://doaj.org/toc/2158-0529 doi:10.21103/Article12(1)_OA19 2158-0510 2158-0529 https://doaj.org/article/a1ed268956904b228a31c1a49391d3c3 |
op_doi |
https://doi.org/10.21103/Article12(1)_OA19 |
container_title |
International Journal of Biomedicine |
container_volume |
12 |
container_issue |
1 |
container_start_page |
155 |
op_container_end_page |
159 |
_version_ |
1766236276925661184 |