Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function
Objective The aim of the study is to assess changes in heart structure and function associated with heavy alcohol use by comparing echocardiographic indices in a population-based sample to those in patients admitted to an inpatient facility with severe alcohol problems.Methods and results We used da...
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ftdoajarticles:oai:doaj.org/article:a1830e6283614984af5a4f8c5f581922 2023-05-15T15:23:43+02:00 Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function Henrik Schirmer Sofia Malyutina Maria Averina David Leon Tom Wilsgaard Olena Iakunchykova Andrew Ryabikov Alexander Kudryavtsev Mikhail Kornev Ekaterina Voronina Andrey Paramonov 2021-06-01T00:00:00Z https://doi.org/10.1136/openhrt-2020-001457 https://doaj.org/article/a1830e6283614984af5a4f8c5f581922 EN eng BMJ Publishing Group https://openheart.bmj.com/content/8/1/e001457.full https://doaj.org/toc/2053-3624 doi:10.1136/openhrt-2020-001457 2053-3624 https://doaj.org/article/a1830e6283614984af5a4f8c5f581922 Open Heart, Vol 8, Iss 1 (2021) Diseases of the circulatory (Cardiovascular) system RC666-701 article 2021 ftdoajarticles https://doi.org/10.1136/openhrt-2020-001457 2022-12-31T06:21:56Z Objective The aim of the study is to assess changes in heart structure and function associated with heavy alcohol use by comparing echocardiographic indices in a population-based sample to those in patients admitted to an inpatient facility with severe alcohol problems.Methods and results We used data from the Know Your Heart study (2015–2017) which is a cross-sectional study that recruited 2479 participants aged 35–69 years from the general population of the city of Arkhangelsk in Northwest Russia and 278 patients from the Arkhangelsk Regional Psychiatric Hospital with a primary diagnosis related to chronic alcohol use (narcology clinic subsample). The drinking patterns of the population-based sample were characterised in detail. We used regression models controlling for age, sex, smoking, education and waist to hip ratio to evaluate the differences in echocardiographic indices in participants with different drinking patterns. The means of left ventricular end-diastolic diameter and indexed left atrial systolic diameter were increased among heavy drinkers (narcology clinic subsample), while mean left ventricular ejection fraction was decreased in this group compared with the population-based sample. In contrast, the harmful and hazardous drinkers in the population-based sample did not differ from non-problem drinkers with respect to echocardiographic indices of systolic and diastolic function.Conclusions Extremely heavy drinking is associated with a specific set of structural and functional abnormalities of the heart that may be regarded as precursors of alcohol-related dilated cardiomyopathy. Article in Journal/Newspaper Arkhangelsk Northwest Russia Directory of Open Access Journals: DOAJ Articles Open Heart 8 1 e001457 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Diseases of the circulatory (Cardiovascular) system RC666-701 |
spellingShingle |
Diseases of the circulatory (Cardiovascular) system RC666-701 Henrik Schirmer Sofia Malyutina Maria Averina David Leon Tom Wilsgaard Olena Iakunchykova Andrew Ryabikov Alexander Kudryavtsev Mikhail Kornev Ekaterina Voronina Andrey Paramonov Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function |
topic_facet |
Diseases of the circulatory (Cardiovascular) system RC666-701 |
description |
Objective The aim of the study is to assess changes in heart structure and function associated with heavy alcohol use by comparing echocardiographic indices in a population-based sample to those in patients admitted to an inpatient facility with severe alcohol problems.Methods and results We used data from the Know Your Heart study (2015–2017) which is a cross-sectional study that recruited 2479 participants aged 35–69 years from the general population of the city of Arkhangelsk in Northwest Russia and 278 patients from the Arkhangelsk Regional Psychiatric Hospital with a primary diagnosis related to chronic alcohol use (narcology clinic subsample). The drinking patterns of the population-based sample were characterised in detail. We used regression models controlling for age, sex, smoking, education and waist to hip ratio to evaluate the differences in echocardiographic indices in participants with different drinking patterns. The means of left ventricular end-diastolic diameter and indexed left atrial systolic diameter were increased among heavy drinkers (narcology clinic subsample), while mean left ventricular ejection fraction was decreased in this group compared with the population-based sample. In contrast, the harmful and hazardous drinkers in the population-based sample did not differ from non-problem drinkers with respect to echocardiographic indices of systolic and diastolic function.Conclusions Extremely heavy drinking is associated with a specific set of structural and functional abnormalities of the heart that may be regarded as precursors of alcohol-related dilated cardiomyopathy. |
format |
Article in Journal/Newspaper |
author |
Henrik Schirmer Sofia Malyutina Maria Averina David Leon Tom Wilsgaard Olena Iakunchykova Andrew Ryabikov Alexander Kudryavtsev Mikhail Kornev Ekaterina Voronina Andrey Paramonov |
author_facet |
Henrik Schirmer Sofia Malyutina Maria Averina David Leon Tom Wilsgaard Olena Iakunchykova Andrew Ryabikov Alexander Kudryavtsev Mikhail Kornev Ekaterina Voronina Andrey Paramonov |
author_sort |
Henrik Schirmer |
title |
Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function |
title_short |
Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function |
title_full |
Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function |
title_fullStr |
Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function |
title_full_unstemmed |
Heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function |
title_sort |
heavy alcohol drinking and subclinical echocardiographic abnormalities of structure and function |
publisher |
BMJ Publishing Group |
publishDate |
2021 |
url |
https://doi.org/10.1136/openhrt-2020-001457 https://doaj.org/article/a1830e6283614984af5a4f8c5f581922 |
genre |
Arkhangelsk Northwest Russia |
genre_facet |
Arkhangelsk Northwest Russia |
op_source |
Open Heart, Vol 8, Iss 1 (2021) |
op_relation |
https://openheart.bmj.com/content/8/1/e001457.full https://doaj.org/toc/2053-3624 doi:10.1136/openhrt-2020-001457 2053-3624 https://doaj.org/article/a1830e6283614984af5a4f8c5f581922 |
op_doi |
https://doi.org/10.1136/openhrt-2020-001457 |
container_title |
Open Heart |
container_volume |
8 |
container_issue |
1 |
container_start_page |
e001457 |
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