Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy?
Gestational diabetes mellitus (GDM) is a serious condition associated to both maternal and offspring complications. Yet, no globally accepted consensus exists on how to test and diagnose GDM. In Greenland, the clinical criteria for testing and diagnosing GDM are adapted from Danish guidelines. The a...
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ftdoajarticles:oai:doaj.org/article:a149e026fb684f2f860c769c2b11926b 2023-05-15T15:12:16+02:00 Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy? Michael Lynge Pedersen Ole Lind Trine Abelsen Jesper Olesen Marit Eika Jørgensen 2018-01-01T00:00:00Z https://doi.org/10.1080/22423982.2018.1528126 https://doaj.org/article/a149e026fb684f2f860c769c2b11926b EN eng Taylor & Francis Group http://dx.doi.org/10.1080/22423982.2018.1528126 https://doaj.org/toc/2242-3982 2242-3982 doi:10.1080/22423982.2018.1528126 https://doaj.org/article/a149e026fb684f2f860c769c2b11926b International Journal of Circumpolar Health, Vol 77, Iss 1 (2018) Gestational diabetes diagnostic prevalence macrosomia overweight inuit Greenland Arctic medicine. Tropical medicine RC955-962 article 2018 ftdoajarticles https://doi.org/10.1080/22423982.2018.1528126 2023-01-08T01:34:03Z Gestational diabetes mellitus (GDM) is a serious condition associated to both maternal and offspring complications. Yet, no globally accepted consensus exists on how to test and diagnose GDM. In Greenland, the clinical criteria for testing and diagnosing GDM are adapted from Danish guidelines. The aim of this study was to estimate the prevalence of GDM among Greenlanders using both the current clinical GDM criteria and the recent WHO 2013 criteria and, further, to study the association between GDM, pre-pregnant overweight or obesity and macrosomia. A cross-sectional study of all 450 Greenlandic women who gave birth to a singleton in Nuuk within 1 year was performed. Based on an oral glucose tolerance test measuring capillary whole blood glucose, 119 women were categorised as having clinical GDM, WHO 2013 GDM or not GDM. Macrosomia defined as birth weight above 4,000 g was used as outcome variable. The prevalence of clinical GDM and WHO 2013 GDM was 0.4% (95% CI; 0–1.1) and 6.9% (95% CI; 4.5–9.2). WHO 2013 GDM, fasting blood glucose, pre-pregnant maternal overweight and obesity were associated with macrosomia. WHO 2013 GDM criteria were superior to clinical criteria in predicting macrosomia indicating that it may be time to consider the diagnostic strategy used in Greenland. Pre-pregnant overweight may also need more intensified lifestyle-intervention. Abbreviations: GDM: Gestational diabetes mellitus; VP: venous plasma; CWB: capillary whole blood; OGTT: oral glucose tolerance test; WHO: World Health Organisation; FIGO: The International Federation of Gynaecology and Obstetrics; BMI: body mass index; GA: gestational age Article in Journal/Newspaper Arctic Circumpolar Health Greenland greenlander* greenlandic International Journal of Circumpolar Health inuit Nuuk Directory of Open Access Journals: DOAJ Articles Arctic Greenland Nuuk ENVELOPE(-52.150,-52.150,68.717,68.717) International Journal of Circumpolar Health 77 1 1528126 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Gestational diabetes diagnostic prevalence macrosomia overweight inuit Greenland Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Gestational diabetes diagnostic prevalence macrosomia overweight inuit Greenland Arctic medicine. Tropical medicine RC955-962 Michael Lynge Pedersen Ole Lind Trine Abelsen Jesper Olesen Marit Eika Jørgensen Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy? |
topic_facet |
Gestational diabetes diagnostic prevalence macrosomia overweight inuit Greenland Arctic medicine. Tropical medicine RC955-962 |
description |
Gestational diabetes mellitus (GDM) is a serious condition associated to both maternal and offspring complications. Yet, no globally accepted consensus exists on how to test and diagnose GDM. In Greenland, the clinical criteria for testing and diagnosing GDM are adapted from Danish guidelines. The aim of this study was to estimate the prevalence of GDM among Greenlanders using both the current clinical GDM criteria and the recent WHO 2013 criteria and, further, to study the association between GDM, pre-pregnant overweight or obesity and macrosomia. A cross-sectional study of all 450 Greenlandic women who gave birth to a singleton in Nuuk within 1 year was performed. Based on an oral glucose tolerance test measuring capillary whole blood glucose, 119 women were categorised as having clinical GDM, WHO 2013 GDM or not GDM. Macrosomia defined as birth weight above 4,000 g was used as outcome variable. The prevalence of clinical GDM and WHO 2013 GDM was 0.4% (95% CI; 0–1.1) and 6.9% (95% CI; 4.5–9.2). WHO 2013 GDM, fasting blood glucose, pre-pregnant maternal overweight and obesity were associated with macrosomia. WHO 2013 GDM criteria were superior to clinical criteria in predicting macrosomia indicating that it may be time to consider the diagnostic strategy used in Greenland. Pre-pregnant overweight may also need more intensified lifestyle-intervention. Abbreviations: GDM: Gestational diabetes mellitus; VP: venous plasma; CWB: capillary whole blood; OGTT: oral glucose tolerance test; WHO: World Health Organisation; FIGO: The International Federation of Gynaecology and Obstetrics; BMI: body mass index; GA: gestational age |
format |
Article in Journal/Newspaper |
author |
Michael Lynge Pedersen Ole Lind Trine Abelsen Jesper Olesen Marit Eika Jørgensen |
author_facet |
Michael Lynge Pedersen Ole Lind Trine Abelsen Jesper Olesen Marit Eika Jørgensen |
author_sort |
Michael Lynge Pedersen |
title |
Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy? |
title_short |
Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy? |
title_full |
Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy? |
title_fullStr |
Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy? |
title_full_unstemmed |
Gestational diabetes and macrosomia among Greenlanders. Time to change diagnostic strategy? |
title_sort |
gestational diabetes and macrosomia among greenlanders. time to change diagnostic strategy? |
publisher |
Taylor & Francis Group |
publishDate |
2018 |
url |
https://doi.org/10.1080/22423982.2018.1528126 https://doaj.org/article/a149e026fb684f2f860c769c2b11926b |
long_lat |
ENVELOPE(-52.150,-52.150,68.717,68.717) |
geographic |
Arctic Greenland Nuuk |
geographic_facet |
Arctic Greenland Nuuk |
genre |
Arctic Circumpolar Health Greenland greenlander* greenlandic International Journal of Circumpolar Health inuit Nuuk |
genre_facet |
Arctic Circumpolar Health Greenland greenlander* greenlandic International Journal of Circumpolar Health inuit Nuuk |
op_source |
International Journal of Circumpolar Health, Vol 77, Iss 1 (2018) |
op_relation |
http://dx.doi.org/10.1080/22423982.2018.1528126 https://doaj.org/toc/2242-3982 2242-3982 doi:10.1080/22423982.2018.1528126 https://doaj.org/article/a149e026fb684f2f860c769c2b11926b |
op_doi |
https://doi.org/10.1080/22423982.2018.1528126 |
container_title |
International Journal of Circumpolar Health |
container_volume |
77 |
container_issue |
1 |
container_start_page |
1528126 |
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1766342978603843584 |