Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin
Introduction This study confirmed the absence of natural infection with Xenotropic murine leukemia virus-related virus (XMRV) or XMRV-related disease in human populations of the Brazilian Amazon basin. We demonstrated that 803 individuals of both sexes, who were residents of Belem in the Brazilian S...
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ftdoajarticles:oai:doaj.org/article:a03c59cca19b40409437184a94a2dcdf 2023-05-15T15:05:08+02:00 Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin Samara Tatielle Monteiro Gomes Luciana Imbiriba Rommel Rodriguéz Burbano Artur Luiz da Costa Silva Rosimar Neris Martins Feitosa Izaura Maria Vieira Cayres-Vallinoto Marluísa de Oliveira Guimarães Ishak Ricardo Ishak Antonio Carlos Rosário Vallinoto 2014-06-01T00:00:00Z https://doi.org/10.1590/0037-8682-0075-2014 https://doaj.org/article/a03c59cca19b40409437184a94a2dcdf EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300302&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0075-2014 https://doaj.org/article/a03c59cca19b40409437184a94a2dcdf Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 3, Pp 302-306 (2014) Xenotropic murine leukemia virus-related virus Retrovirus Amazon region Brazil Arctic medicine. Tropical medicine RC955-962 article 2014 ftdoajarticles https://doi.org/10.1590/0037-8682-0075-2014 2022-12-31T02:52:58Z Introduction This study confirmed the absence of natural infection with Xenotropic murine leukemia virus-related virus (XMRV) or XMRV-related disease in human populations of the Brazilian Amazon basin. We demonstrated that 803 individuals of both sexes, who were residents of Belem in the Brazilian State of Pará, were not infected with XMRV. Methods Individuals were divided into 4 subgroups: healthy individuals, individuals infected with human immunodeficiency virus, type 1 (HIV-1), individuals infected with human T-lymphotrophic virus, types 1 or 2 (HTLV-1/2), and individuals with prostate cancer. XMRV infection was investigated by nested PCR to detect the viral gag gene and by quantitative PCR to detect pol. Results There was no amplification of either gag or pol segments from XRMV in any of the samples examined. Conclusions This study supports the conclusions of the studies that eventually led to the retraction of the original study reporting the association between XMRV and human diseases. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 47 3 302 306 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Xenotropic murine leukemia virus-related virus Retrovirus Amazon region Brazil Arctic medicine. Tropical medicine RC955-962 |
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Xenotropic murine leukemia virus-related virus Retrovirus Amazon region Brazil Arctic medicine. Tropical medicine RC955-962 Samara Tatielle Monteiro Gomes Luciana Imbiriba Rommel Rodriguéz Burbano Artur Luiz da Costa Silva Rosimar Neris Martins Feitosa Izaura Maria Vieira Cayres-Vallinoto Marluísa de Oliveira Guimarães Ishak Ricardo Ishak Antonio Carlos Rosário Vallinoto Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin |
topic_facet |
Xenotropic murine leukemia virus-related virus Retrovirus Amazon region Brazil Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction This study confirmed the absence of natural infection with Xenotropic murine leukemia virus-related virus (XMRV) or XMRV-related disease in human populations of the Brazilian Amazon basin. We demonstrated that 803 individuals of both sexes, who were residents of Belem in the Brazilian State of Pará, were not infected with XMRV. Methods Individuals were divided into 4 subgroups: healthy individuals, individuals infected with human immunodeficiency virus, type 1 (HIV-1), individuals infected with human T-lymphotrophic virus, types 1 or 2 (HTLV-1/2), and individuals with prostate cancer. XMRV infection was investigated by nested PCR to detect the viral gag gene and by quantitative PCR to detect pol. Results There was no amplification of either gag or pol segments from XRMV in any of the samples examined. Conclusions This study supports the conclusions of the studies that eventually led to the retraction of the original study reporting the association between XMRV and human diseases. |
format |
Article in Journal/Newspaper |
author |
Samara Tatielle Monteiro Gomes Luciana Imbiriba Rommel Rodriguéz Burbano Artur Luiz da Costa Silva Rosimar Neris Martins Feitosa Izaura Maria Vieira Cayres-Vallinoto Marluísa de Oliveira Guimarães Ishak Ricardo Ishak Antonio Carlos Rosário Vallinoto |
author_facet |
Samara Tatielle Monteiro Gomes Luciana Imbiriba Rommel Rodriguéz Burbano Artur Luiz da Costa Silva Rosimar Neris Martins Feitosa Izaura Maria Vieira Cayres-Vallinoto Marluísa de Oliveira Guimarães Ishak Ricardo Ishak Antonio Carlos Rosário Vallinoto |
author_sort |
Samara Tatielle Monteiro Gomes |
title |
Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin |
title_short |
Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin |
title_full |
Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin |
title_fullStr |
Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin |
title_full_unstemmed |
Lack of evidence for human infection with Xenotropic murine leukemia virus-related virus in the Brazilian Amazon basin |
title_sort |
lack of evidence for human infection with xenotropic murine leukemia virus-related virus in the brazilian amazon basin |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2014 |
url |
https://doi.org/10.1590/0037-8682-0075-2014 https://doaj.org/article/a03c59cca19b40409437184a94a2dcdf |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 47, Iss 3, Pp 302-306 (2014) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300302&lng=en&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0075-2014 https://doaj.org/article/a03c59cca19b40409437184a94a2dcdf |
op_doi |
https://doi.org/10.1590/0037-8682-0075-2014 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
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47 |
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3 |
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302 |
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