Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016.
A total of 1,596 laboratory-confirmed imported dengue cases were identified in Taiwan during 2011-2016. Most of the imported cases arrived from Southeast Asia as well as the Indian subcontinent, the Pacific region, Latin America, Australia and Africa. Phylogenetic analyses of the complete envelope p...
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ftdoajarticles:oai:doaj.org/article:9f15f435950648c785914c355ecffd9e 2023-05-15T15:06:05+02:00 Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016. Cheng-Fen Yang Shu-Fen Chang Tung-Chien Hsu Chien-Ling Su Tzy-Chen Wang Shih-Hung Lin Su-Lin Yang Chien-Chou Lin Pei-Yun Shu 2018-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0006773 https://doaj.org/article/9f15f435950648c785914c355ecffd9e EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC6168156?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006773 https://doaj.org/article/9f15f435950648c785914c355ecffd9e PLoS Neglected Tropical Diseases, Vol 12, Iss 9, p e0006773 (2018) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2018 ftdoajarticles https://doi.org/10.1371/journal.pntd.0006773 2022-12-31T00:23:26Z A total of 1,596 laboratory-confirmed imported dengue cases were identified in Taiwan during 2011-2016. Most of the imported cases arrived from Southeast Asia as well as the Indian subcontinent, the Pacific region, Latin America, Australia and Africa. Phylogenetic analyses of the complete envelope protein gene sequences from 784 imported dengue virus (DENV) isolates were conducted, and the results suggest that the DENV-1 genotype I and DENV-2 Cosmopolitan genotype comprise the predominant serotype/genotype of DENV strains circulating in Southeast Asia. The DENV-1 genotype III, DENV-3 genotype III and DENV-4 genotype I and II strains were found to be newly emerging in several Southeast Asian countries. Our results also showed that geographical restrictions of DENV-1 genotype I, DENV-1 genotype III and DENV-2 Cosmopolitan genotype are becoming blurred, indicating the extensive introductions and continuous expansions of DENV strains between nations in Southeast Asia. In this study, we present the geographic distribution and dynamic transmission of DENV strains circulating in Southeast Asian countries. In addition, we demonstrated local dengue epidemics caused by several imported DENV strains in Taiwan during 2011-2016. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Pacific Indian PLOS Neglected Tropical Diseases 12 9 e0006773 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Cheng-Fen Yang Shu-Fen Chang Tung-Chien Hsu Chien-Ling Su Tzy-Chen Wang Shih-Hung Lin Su-Lin Yang Chien-Chou Lin Pei-Yun Shu Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
A total of 1,596 laboratory-confirmed imported dengue cases were identified in Taiwan during 2011-2016. Most of the imported cases arrived from Southeast Asia as well as the Indian subcontinent, the Pacific region, Latin America, Australia and Africa. Phylogenetic analyses of the complete envelope protein gene sequences from 784 imported dengue virus (DENV) isolates were conducted, and the results suggest that the DENV-1 genotype I and DENV-2 Cosmopolitan genotype comprise the predominant serotype/genotype of DENV strains circulating in Southeast Asia. The DENV-1 genotype III, DENV-3 genotype III and DENV-4 genotype I and II strains were found to be newly emerging in several Southeast Asian countries. Our results also showed that geographical restrictions of DENV-1 genotype I, DENV-1 genotype III and DENV-2 Cosmopolitan genotype are becoming blurred, indicating the extensive introductions and continuous expansions of DENV strains between nations in Southeast Asia. In this study, we present the geographic distribution and dynamic transmission of DENV strains circulating in Southeast Asian countries. In addition, we demonstrated local dengue epidemics caused by several imported DENV strains in Taiwan during 2011-2016. |
format |
Article in Journal/Newspaper |
author |
Cheng-Fen Yang Shu-Fen Chang Tung-Chien Hsu Chien-Ling Su Tzy-Chen Wang Shih-Hung Lin Su-Lin Yang Chien-Chou Lin Pei-Yun Shu |
author_facet |
Cheng-Fen Yang Shu-Fen Chang Tung-Chien Hsu Chien-Ling Su Tzy-Chen Wang Shih-Hung Lin Su-Lin Yang Chien-Chou Lin Pei-Yun Shu |
author_sort |
Cheng-Fen Yang |
title |
Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016. |
title_short |
Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016. |
title_full |
Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016. |
title_fullStr |
Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016. |
title_full_unstemmed |
Molecular characterization and phylogenetic analysis of dengue viruses imported into Taiwan during 2011-2016. |
title_sort |
molecular characterization and phylogenetic analysis of dengue viruses imported into taiwan during 2011-2016. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2018 |
url |
https://doi.org/10.1371/journal.pntd.0006773 https://doaj.org/article/9f15f435950648c785914c355ecffd9e |
geographic |
Arctic Pacific Indian |
geographic_facet |
Arctic Pacific Indian |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 12, Iss 9, p e0006773 (2018) |
op_relation |
http://europepmc.org/articles/PMC6168156?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006773 https://doaj.org/article/9f15f435950648c785914c355ecffd9e |
op_doi |
https://doi.org/10.1371/journal.pntd.0006773 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
12 |
container_issue |
9 |
container_start_page |
e0006773 |
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1766337742729379840 |