Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum

Abstract Background The aim of the present work was to assess i) ex vivo activity of pyronaridine (PND) and piperaquine (PPQ), as new components of artemisinin-based combination therapy (ACT), to define susceptibility baseline, ii) their activities compared to other partner drugs, namely monodesethy...

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Bibliographic Details
Published in:Malaria Journal
Main Authors: Pascual Aurélie, Parola Philippe, Benoit-Vical Françoise, Simon Fabrice, Malvy Denis, Picot Stéphane, Delaunay Pascal, Basset Didier, Maubon Danièle, Faugère Bernard, Ménard Guillaume, Bourgeois Nathalie, Oeuvray Claude, Didillon Eric, Rogier Christophe, Pradines Bruno
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2012
Subjects:
Malaria
Plasmodium falciparum
Anti-malarial
In vitro
Resistance
Pyronaridine
Piperaquine
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Rho
Online Access:https://doi.org/10.1186/1475-2875-11-45
https://doaj.org/article/9ec13234059144b18c4e63182e29403b

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