Parotid enlargement due to adenovirus infection in patient with human immunodeficiency virus infection

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Maria Irma Seixas Duarte, Valdir Sabbaga Amato, Juliane Gomes de Paula, David Everson Uip, Marcos Boulos, Vicente Amato Neto
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1996
• Subjects: Vírus da imunodeficiência humana; Adenovirus; Parótida; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/S0037-86821996000500015; https://doaj.org/article/9e43361445d849cf95e5bbe6ee557c07

The authors report a case of adenovirus- induced enlargement of the parotid gland involving a patient infected with human immunodeficiency virus (HIV). Physical examination revealed good general condition, no fever and bilateral enlargement of the parotid region, which was of increased consistency and slightly tender to palpation. Histological examination of the parotid gland demonstrated a slight periductal lymphomononuclear inflammatory infiltrate with the presence of focal points of necrosis. Tests to determine the presence of fungi and alcohol-acid resistent bacilli were negative. Immunohistochemistry for cytomegalovirus, heipes simplex, HIV p24 antigen and adenovirus showed positivity only for adenovirus in the epithelial nuclei of numerous gland ducts. Tins is the third case of this type reported in the literature, indicating the importance of including adenovirus in the differential diagnosis of this condition.