CoMM: A Collaborative Mixed Model That Integrates GWAS and eQTL Data Sets to Investigate the Genetic Architecture of Complex Traits

• Published in: Bioinformatics and Biology Insights
• Main Authors: Kar-Fu Yeung, Yi Yang, Can Yang, Jin Liu
• Format: Article in Journal/Newspaper
• Language: English
• Published: SAGE Publishing 2019
• Subjects: Biology (General); QH301-705.5; Handle The; Northern Finland
• Online Access: https://doi.org/10.1177/1177932219881435; https://doaj.org/article/9e3354128f024f49875224af87555164

Genome-wide association study (GWAS) analyses have identified thousands of associations between genetic variants and complex traits. However, it is still a challenge to uncover the mechanisms underlying the association. With the growing availability of transcriptome data sets, it has become possible...