Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar)
Abstract Background Puberty in male Atlantic salmon in aquaculture can start as early as after the first winter in seawater, stunts growth and entails welfare problems due to the maturation-associated loss of osmoregulation capacity in seawater. A better understanding of the regulation of puberty is...
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ftdoajarticles:oai:doaj.org/article:9d3aa4dbba924196a9ad1b36a9bd5661 2023-05-15T15:31:15+02:00 Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar) Rüdiger W. Schulz Geir Lasse Taranger Jan Bogerd Wouter Nijenhuis Birgitta Norberg Rune Male Eva Andersson 2019-06-01T00:00:00Z https://doi.org/10.1186/s12958-019-0493-8 https://doaj.org/article/9d3aa4dbba924196a9ad1b36a9bd5661 EN eng BMC http://link.springer.com/article/10.1186/s12958-019-0493-8 https://doaj.org/toc/1477-7827 doi:10.1186/s12958-019-0493-8 1477-7827 https://doaj.org/article/9d3aa4dbba924196a9ad1b36a9bd5661 Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-16 (2019) Photoperiod Puberty Spermatogenesis Gonadotropins Androgens Growth factors Gynecology and obstetrics RG1-991 Reproduction QH471-489 article 2019 ftdoajarticles https://doi.org/10.1186/s12958-019-0493-8 2022-12-31T04:02:11Z Abstract Background Puberty in male Atlantic salmon in aquaculture can start as early as after the first winter in seawater, stunts growth and entails welfare problems due to the maturation-associated loss of osmoregulation capacity in seawater. A better understanding of the regulation of puberty is the basis for developing improved cultivation approaches that avoid these problems. Our aim here was to identify morphological and molecular markers signaling the initiation of, and potential involvement in, testis maturation. Methods In the first experiment, we monitored for the first time in large Atlantic salmon males several reproductive parameters during 17 months including the first reproductive cycle. Since testicular growth accelerated after the Winter solstice, we focused in the second experiment on the 5 months following the winter solstice, exposing fish from February 1 onwards to the natural photoperiod (NL) or to continuous additional light (LL). Results In the first experiment, testis weight, plasma androgens and pituitary gonadotropin transcript levels increased with the appearance of type B spermatogonia in the testis, but testicular transcript levels for gonadotropin or androgen receptors did not change while being clearly detectable. In the second experiment, all males kept under NL had been recruited into puberty until June. However, recruitment into puberty was blocked in ~ 40% of the males exposed to LL. The first morphological sign of recruitment was an increased proliferation activity of single spermatogonia and Sertoli cells. Irrespective of the photoperiod, this early sign of testis maturation was accompanied by elevated pituitary gnrhr4 and fshb and testicular igf3 transcript levels as well as increased plasma androgen levels. The transition into puberty occurred again with stable testicular gonadotropin and androgen receptor transcript levels. Conclusions The sensitivity to reproductive hormones is already established before puberty starts and up-regulation of testicular hormone receptor ... Article in Journal/Newspaper Atlantic salmon Salmo salar Directory of Open Access Journals: DOAJ Articles Reproductive Biology and Endocrinology 17 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Photoperiod Puberty Spermatogenesis Gonadotropins Androgens Growth factors Gynecology and obstetrics RG1-991 Reproduction QH471-489 |
spellingShingle |
Photoperiod Puberty Spermatogenesis Gonadotropins Androgens Growth factors Gynecology and obstetrics RG1-991 Reproduction QH471-489 Rüdiger W. Schulz Geir Lasse Taranger Jan Bogerd Wouter Nijenhuis Birgitta Norberg Rune Male Eva Andersson Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar) |
topic_facet |
Photoperiod Puberty Spermatogenesis Gonadotropins Androgens Growth factors Gynecology and obstetrics RG1-991 Reproduction QH471-489 |
description |
Abstract Background Puberty in male Atlantic salmon in aquaculture can start as early as after the first winter in seawater, stunts growth and entails welfare problems due to the maturation-associated loss of osmoregulation capacity in seawater. A better understanding of the regulation of puberty is the basis for developing improved cultivation approaches that avoid these problems. Our aim here was to identify morphological and molecular markers signaling the initiation of, and potential involvement in, testis maturation. Methods In the first experiment, we monitored for the first time in large Atlantic salmon males several reproductive parameters during 17 months including the first reproductive cycle. Since testicular growth accelerated after the Winter solstice, we focused in the second experiment on the 5 months following the winter solstice, exposing fish from February 1 onwards to the natural photoperiod (NL) or to continuous additional light (LL). Results In the first experiment, testis weight, plasma androgens and pituitary gonadotropin transcript levels increased with the appearance of type B spermatogonia in the testis, but testicular transcript levels for gonadotropin or androgen receptors did not change while being clearly detectable. In the second experiment, all males kept under NL had been recruited into puberty until June. However, recruitment into puberty was blocked in ~ 40% of the males exposed to LL. The first morphological sign of recruitment was an increased proliferation activity of single spermatogonia and Sertoli cells. Irrespective of the photoperiod, this early sign of testis maturation was accompanied by elevated pituitary gnrhr4 and fshb and testicular igf3 transcript levels as well as increased plasma androgen levels. The transition into puberty occurred again with stable testicular gonadotropin and androgen receptor transcript levels. Conclusions The sensitivity to reproductive hormones is already established before puberty starts and up-regulation of testicular hormone receptor ... |
format |
Article in Journal/Newspaper |
author |
Rüdiger W. Schulz Geir Lasse Taranger Jan Bogerd Wouter Nijenhuis Birgitta Norberg Rune Male Eva Andersson |
author_facet |
Rüdiger W. Schulz Geir Lasse Taranger Jan Bogerd Wouter Nijenhuis Birgitta Norberg Rune Male Eva Andersson |
author_sort |
Rüdiger W. Schulz |
title |
Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar) |
title_short |
Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar) |
title_full |
Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar) |
title_fullStr |
Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar) |
title_full_unstemmed |
Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar) |
title_sort |
entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in atlantic salmon (salmo salar) |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s12958-019-0493-8 https://doaj.org/article/9d3aa4dbba924196a9ad1b36a9bd5661 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-16 (2019) |
op_relation |
http://link.springer.com/article/10.1186/s12958-019-0493-8 https://doaj.org/toc/1477-7827 doi:10.1186/s12958-019-0493-8 1477-7827 https://doaj.org/article/9d3aa4dbba924196a9ad1b36a9bd5661 |
op_doi |
https://doi.org/10.1186/s12958-019-0493-8 |
container_title |
Reproductive Biology and Endocrinology |
container_volume |
17 |
container_issue |
1 |
_version_ |
1766361738314252288 |