Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study
Objective. To identify socio-demographic and clinical factors associated with mortality among persons with tuberculosis (TB) and TB/HIV co-infection in Suriname. Methods. This was a retrospective cohort study using data from the national TB and HIV databases for 2010 – 2015. The survival probability...
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ftdoajarticles:oai:doaj.org/article:9cacba9a1e0d46ba893fd168315a10f1 2023-05-15T15:09:18+02:00 Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study Deborah Stijnberg Eric Commiesie Diana Marín Ward Schrooten Freddy Perez Mauro Sanchez 2019-12-01T00:00:00Z https://doi.org/10.26633/RPSP.2019.103 https://doaj.org/article/9cacba9a1e0d46ba893fd168315a10f1 EN ES PT eng spa por Pan American Health Organization http://iris.paho.org/xmlui/handle/123456789/51755 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2019.103 https://doaj.org/article/9cacba9a1e0d46ba893fd168315a10f1 Revista Panamericana de Salud Pública, Vol 43, Iss 1, Pp 1-9 (2019) tuberculosis hiv mortality national health programs suriname Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.26633/RPSP.2019.103 2022-12-31T01:32:16Z Objective. To identify socio-demographic and clinical factors associated with mortality among persons with tuberculosis (TB) and TB/HIV co-infection in Suriname. Methods. This was a retrospective cohort study using data from the national TB and HIV databases for 2010 – 2015. The survival probability of TB and TB/HIV co-infected patients was analyzed using the Kaplan-Meier estimates and the log-rank test. A Cox proportional hazard model was applied. Results. The study showed that HIV-seropositivity (aHR: 2.08, 95%CI: 1.48 – 2.92) and older age (aHR: 5.84, 95%CI: 3.00 – 11.4) are statistically associated with higher mortality. For the TB/HIV co-infected patients, TB treatment (aHR: 0.43, 95%CI: 0.35 – 0.53) reduces the risk of death. Similarly, HIV treatment started within 56 days (aHR: 0.15, 95%CI: 0.12 – 0.19) and delayed (aHR: 0.25, 95%CI: 0.13 – 0.47) result in less hazard for mortality; Directly-Observed Treatment (aOR: 0.16, 95%CI: 0.09 – 0.29) further reduces the risk. Conclusions. The Ministry of Health of Suriname should develop strategies for early case-finding in key populations, such as for HIV and TB in men 60 years of age and older. Implementation of Isoniazid Preventive Therapy for HIV should be pursued. Scaling up TB and HIV treatment, preferably through supervision, are essential to reducing the TB/HIV mortality. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Meier ENVELOPE(-45.900,-45.900,-60.633,-60.633) Revista Panamericana de Salud Pública 43 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish Portuguese |
topic |
tuberculosis hiv mortality national health programs suriname Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
tuberculosis hiv mortality national health programs suriname Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Deborah Stijnberg Eric Commiesie Diana Marín Ward Schrooten Freddy Perez Mauro Sanchez Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study |
topic_facet |
tuberculosis hiv mortality national health programs suriname Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Objective. To identify socio-demographic and clinical factors associated with mortality among persons with tuberculosis (TB) and TB/HIV co-infection in Suriname. Methods. This was a retrospective cohort study using data from the national TB and HIV databases for 2010 – 2015. The survival probability of TB and TB/HIV co-infected patients was analyzed using the Kaplan-Meier estimates and the log-rank test. A Cox proportional hazard model was applied. Results. The study showed that HIV-seropositivity (aHR: 2.08, 95%CI: 1.48 – 2.92) and older age (aHR: 5.84, 95%CI: 3.00 – 11.4) are statistically associated with higher mortality. For the TB/HIV co-infected patients, TB treatment (aHR: 0.43, 95%CI: 0.35 – 0.53) reduces the risk of death. Similarly, HIV treatment started within 56 days (aHR: 0.15, 95%CI: 0.12 – 0.19) and delayed (aHR: 0.25, 95%CI: 0.13 – 0.47) result in less hazard for mortality; Directly-Observed Treatment (aOR: 0.16, 95%CI: 0.09 – 0.29) further reduces the risk. Conclusions. The Ministry of Health of Suriname should develop strategies for early case-finding in key populations, such as for HIV and TB in men 60 years of age and older. Implementation of Isoniazid Preventive Therapy for HIV should be pursued. Scaling up TB and HIV treatment, preferably through supervision, are essential to reducing the TB/HIV mortality. |
format |
Article in Journal/Newspaper |
author |
Deborah Stijnberg Eric Commiesie Diana Marín Ward Schrooten Freddy Perez Mauro Sanchez |
author_facet |
Deborah Stijnberg Eric Commiesie Diana Marín Ward Schrooten Freddy Perez Mauro Sanchez |
author_sort |
Deborah Stijnberg |
title |
Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study |
title_short |
Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study |
title_full |
Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study |
title_fullStr |
Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study |
title_full_unstemmed |
Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study |
title_sort |
factors associated with mortality in persons co-infected with tuberculosis and hiv in suriname: a retrospective cohort study |
publisher |
Pan American Health Organization |
publishDate |
2019 |
url |
https://doi.org/10.26633/RPSP.2019.103 https://doaj.org/article/9cacba9a1e0d46ba893fd168315a10f1 |
long_lat |
ENVELOPE(-45.900,-45.900,-60.633,-60.633) |
geographic |
Arctic Meier |
geographic_facet |
Arctic Meier |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 43, Iss 1, Pp 1-9 (2019) |
op_relation |
http://iris.paho.org/xmlui/handle/123456789/51755 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2019.103 https://doaj.org/article/9cacba9a1e0d46ba893fd168315a10f1 |
op_doi |
https://doi.org/10.26633/RPSP.2019.103 |
container_title |
Revista Panamericana de Salud Pública |
container_volume |
43 |
container_start_page |
1 |
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1766340506410811392 |