Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog
Canine distemper virus (CDV) is a major viral pathogen in domestic dogs, belonging to the Paramyxoviridae family, in the Morbillivirus genus. It is present worldwide, and a wide range of domestic animals and wild carnivores are at risk. In the absence of vaccination, dogs have a low chance of surviv...
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MDPI AG
2021
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Online Access: | https://doi.org/10.3390/vetsci8040061 https://doaj.org/article/9c3bc53273ac410b8ade9fa1db74eb77 |
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ftdoajarticles:oai:doaj.org/article:9c3bc53273ac410b8ade9fa1db74eb77 2023-05-15T14:57:43+02:00 Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog Zsófia Lanszki Brigitta Zana Safia Zeghbib Ferenc Jakab Nikoletta Szabó Gábor Kemenesi 2021-04-01T00:00:00Z https://doi.org/10.3390/vetsci8040061 https://doaj.org/article/9c3bc53273ac410b8ade9fa1db74eb77 EN eng MDPI AG https://www.mdpi.com/2306-7381/8/4/61 https://doaj.org/toc/2306-7381 doi:10.3390/vetsci8040061 2306-7381 https://doaj.org/article/9c3bc53273ac410b8ade9fa1db74eb77 Veterinary Sciences, Vol 8, Iss 61, p 61 (2021) Paramyxoviridae Morbillivirus canine distemper virus haemagglutinin gene arctic-like lineage domestic dog Veterinary medicine SF600-1100 article 2021 ftdoajarticles https://doi.org/10.3390/vetsci8040061 2022-12-31T10:59:11Z Canine distemper virus (CDV) is a major viral pathogen in domestic dogs, belonging to the Paramyxoviridae family, in the Morbillivirus genus. It is present worldwide, and a wide range of domestic animals and wild carnivores are at risk. In the absence of vaccination, dogs have a low chance of survival; however, if and when a dog survives, it can take an average of a few weeks to a few months to fully wipe out the virus. In the present study, we traced the course of infection of a 1-year-old mixed-breed male dog. The animal had an unusually long course of persistent CDV infection with a vector-borne heartworm ( Dirofilaria immitis ) co-infection. The dog excreted the CDV for 17 months with PCR positivity in urine samples collected from February 2019 through June 2020. The sequencing and phylogenetic analysis of the hemagglutinin gene revealed the CDV to be the member of the endemic Arctic-like genetic lineage. To the best of our knowledge, this report represents the longest documented canine infection of CDV. Notably, we highlight the necessity regarding CDV infectivity studies to better comprehend the transmission attributes of the virus. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Veterinary Sciences 8 4 61 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Paramyxoviridae Morbillivirus canine distemper virus haemagglutinin gene arctic-like lineage domestic dog Veterinary medicine SF600-1100 |
spellingShingle |
Paramyxoviridae Morbillivirus canine distemper virus haemagglutinin gene arctic-like lineage domestic dog Veterinary medicine SF600-1100 Zsófia Lanszki Brigitta Zana Safia Zeghbib Ferenc Jakab Nikoletta Szabó Gábor Kemenesi Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog |
topic_facet |
Paramyxoviridae Morbillivirus canine distemper virus haemagglutinin gene arctic-like lineage domestic dog Veterinary medicine SF600-1100 |
description |
Canine distemper virus (CDV) is a major viral pathogen in domestic dogs, belonging to the Paramyxoviridae family, in the Morbillivirus genus. It is present worldwide, and a wide range of domestic animals and wild carnivores are at risk. In the absence of vaccination, dogs have a low chance of survival; however, if and when a dog survives, it can take an average of a few weeks to a few months to fully wipe out the virus. In the present study, we traced the course of infection of a 1-year-old mixed-breed male dog. The animal had an unusually long course of persistent CDV infection with a vector-borne heartworm ( Dirofilaria immitis ) co-infection. The dog excreted the CDV for 17 months with PCR positivity in urine samples collected from February 2019 through June 2020. The sequencing and phylogenetic analysis of the hemagglutinin gene revealed the CDV to be the member of the endemic Arctic-like genetic lineage. To the best of our knowledge, this report represents the longest documented canine infection of CDV. Notably, we highlight the necessity regarding CDV infectivity studies to better comprehend the transmission attributes of the virus. |
format |
Article in Journal/Newspaper |
author |
Zsófia Lanszki Brigitta Zana Safia Zeghbib Ferenc Jakab Nikoletta Szabó Gábor Kemenesi |
author_facet |
Zsófia Lanszki Brigitta Zana Safia Zeghbib Ferenc Jakab Nikoletta Szabó Gábor Kemenesi |
author_sort |
Zsófia Lanszki |
title |
Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog |
title_short |
Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog |
title_full |
Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog |
title_fullStr |
Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog |
title_full_unstemmed |
Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog |
title_sort |
prolonged infection of canine distemper virus in a mixed-breed dog |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doi.org/10.3390/vetsci8040061 https://doaj.org/article/9c3bc53273ac410b8ade9fa1db74eb77 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Veterinary Sciences, Vol 8, Iss 61, p 61 (2021) |
op_relation |
https://www.mdpi.com/2306-7381/8/4/61 https://doaj.org/toc/2306-7381 doi:10.3390/vetsci8040061 2306-7381 https://doaj.org/article/9c3bc53273ac410b8ade9fa1db74eb77 |
op_doi |
https://doi.org/10.3390/vetsci8040061 |
container_title |
Veterinary Sciences |
container_volume |
8 |
container_issue |
4 |
container_start_page |
61 |
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1766329846119530496 |