Prevalence of Trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the Department of Casanare (Colombia).

The purpose of this study was to calculate the seroprevalence of Trypanosoma cruzi infection in a sample of inhabitants from a region considered to be at high risk of natural transmission of Chagas disease in Colombia. A cross-sectional study was conducted in subjects from 5 municipalities, recruite...

Full description

Bibliographic Details
Published in:PLoS Neglected Tropical Diseases
Main Authors: Fredy Roberto Salazar Gutierrez, Martha Liliana Trujillo Güiza, Magally del Carmen Escobar Martínez
Format: Article in Journal/Newspaper
Language:English
Published: Public Library of Science (PLoS) 2013
Subjects:
Online Access:https://doi.org/10.1371/journal.pntd.0002113
https://doaj.org/article/9bd958e3516f482596cade9d024299fd
id ftdoajarticles:oai:doaj.org/article:9bd958e3516f482596cade9d024299fd
record_format openpolar
spelling ftdoajarticles:oai:doaj.org/article:9bd958e3516f482596cade9d024299fd 2023-05-15T15:10:41+02:00 Prevalence of Trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the Department of Casanare (Colombia). Fredy Roberto Salazar Gutierrez Martha Liliana Trujillo Güiza Magally del Carmen Escobar Martínez 2013-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002113 https://doaj.org/article/9bd958e3516f482596cade9d024299fd EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3591340?pdf=render https://doaj.org/toc/1935-2735 1935-2735 doi:10.1371/journal.pntd.0002113 https://doaj.org/article/9bd958e3516f482596cade9d024299fd PLoS Neglected Tropical Diseases, Vol 7, Iss 3, p e2113 (2013) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2013 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002113 2022-12-30T20:58:54Z The purpose of this study was to calculate the seroprevalence of Trypanosoma cruzi infection in a sample of inhabitants from a region considered to be at high risk of natural transmission of Chagas disease in Colombia. A cross-sectional study was conducted in subjects from 5 municipalities, recruited in urban and rural locations, distributed by gender according to the demographic information available. Socio-demographic information, history of potential exposure to insect vectors, blood donating, as well as symptoms suggesting cardiac disease were collected using a questionnaire. After giving written informed consent, blood specimens were obtained from 486 people to determine the serologic evidence of past exposure to T. cruzi. Infection was diagnosed when two different tests (ELISA and IHA) were positive. The seroprevalence of antibodies against T. cruzi was 16.91% considering an estimated population of 44,355 aged between 15 and 89 years (95%IC: 13.72 to 20.01). The factors significantly associated with the infection were: 1- Housing materials like vegetable material, adobe or unfinished brick walls; 2- The fact of having previous tests for Chagas disease (regardless of the result). Of note, the mean ages among infected and not infected participants were significantly different (49.19 vs. 41.66, p ≤ 0.0001). Among the studied municipalities, the one with the highest frequency of T. cruzi infection was Nunchia, with 31.15% of the surveyed subjects. Therefore it may be concluded that T. cruzi infection is highly prevalent in the north region of Casanare, in Colombia. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 7 3 e2113
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
spellingShingle Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Fredy Roberto Salazar Gutierrez
Martha Liliana Trujillo Güiza
Magally del Carmen Escobar Martínez
Prevalence of Trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the Department of Casanare (Colombia).
topic_facet Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
description The purpose of this study was to calculate the seroprevalence of Trypanosoma cruzi infection in a sample of inhabitants from a region considered to be at high risk of natural transmission of Chagas disease in Colombia. A cross-sectional study was conducted in subjects from 5 municipalities, recruited in urban and rural locations, distributed by gender according to the demographic information available. Socio-demographic information, history of potential exposure to insect vectors, blood donating, as well as symptoms suggesting cardiac disease were collected using a questionnaire. After giving written informed consent, blood specimens were obtained from 486 people to determine the serologic evidence of past exposure to T. cruzi. Infection was diagnosed when two different tests (ELISA and IHA) were positive. The seroprevalence of antibodies against T. cruzi was 16.91% considering an estimated population of 44,355 aged between 15 and 89 years (95%IC: 13.72 to 20.01). The factors significantly associated with the infection were: 1- Housing materials like vegetable material, adobe or unfinished brick walls; 2- The fact of having previous tests for Chagas disease (regardless of the result). Of note, the mean ages among infected and not infected participants were significantly different (49.19 vs. 41.66, p ≤ 0.0001). Among the studied municipalities, the one with the highest frequency of T. cruzi infection was Nunchia, with 31.15% of the surveyed subjects. Therefore it may be concluded that T. cruzi infection is highly prevalent in the north region of Casanare, in Colombia.
format Article in Journal/Newspaper
author Fredy Roberto Salazar Gutierrez
Martha Liliana Trujillo Güiza
Magally del Carmen Escobar Martínez
author_facet Fredy Roberto Salazar Gutierrez
Martha Liliana Trujillo Güiza
Magally del Carmen Escobar Martínez
author_sort Fredy Roberto Salazar Gutierrez
title Prevalence of Trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the Department of Casanare (Colombia).
title_short Prevalence of Trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the Department of Casanare (Colombia).
title_full Prevalence of Trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the Department of Casanare (Colombia).
title_fullStr Prevalence of Trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the Department of Casanare (Colombia).
title_full_unstemmed Prevalence of Trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the Department of Casanare (Colombia).
title_sort prevalence of trypanosoma cruzi infection among people aged 15 to 89 years inhabiting the department of casanare (colombia).
publisher Public Library of Science (PLoS)
publishDate 2013
url https://doi.org/10.1371/journal.pntd.0002113
https://doaj.org/article/9bd958e3516f482596cade9d024299fd
geographic Arctic
geographic_facet Arctic
genre Arctic
genre_facet Arctic
op_source PLoS Neglected Tropical Diseases, Vol 7, Iss 3, p e2113 (2013)
op_relation http://europepmc.org/articles/PMC3591340?pdf=render
https://doaj.org/toc/1935-2735
1935-2735
doi:10.1371/journal.pntd.0002113
https://doaj.org/article/9bd958e3516f482596cade9d024299fd
op_doi https://doi.org/10.1371/journal.pntd.0002113
container_title PLoS Neglected Tropical Diseases
container_volume 7
container_issue 3
container_start_page e2113
_version_ 1766341666519646208