Antibiotic-Induced Perturbations Are Manifested in the Dominant Intestinal Bacterial Phyla of Atlantic Salmon
The intestinal microbiota of certain farmed fish are often exposed to antimicrobial substances, such as antibiotics, that are used to prevent and treat bacterial diseases. Antibiotics that kill or inhibit the growth of harmful microbes can rapidly alter intestinal microbial diversity and composition...
Published in: | Microorganisms |
---|---|
Main Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
MDPI AG
2019
|
Subjects: | |
Online Access: | https://doi.org/10.3390/microorganisms7080233 https://doaj.org/article/9bd487734a4b4c6187f02d830683dd35 |
id |
ftdoajarticles:oai:doaj.org/article:9bd487734a4b4c6187f02d830683dd35 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:9bd487734a4b4c6187f02d830683dd35 2023-05-15T15:30:17+02:00 Antibiotic-Induced Perturbations Are Manifested in the Dominant Intestinal Bacterial Phyla of Atlantic Salmon Shruti Gupta Jorge Fernandes Viswanath Kiron 2019-08-01T00:00:00Z https://doi.org/10.3390/microorganisms7080233 https://doaj.org/article/9bd487734a4b4c6187f02d830683dd35 EN eng MDPI AG https://www.mdpi.com/2076-2607/7/8/233 https://doaj.org/toc/2076-2607 2076-2607 doi:10.3390/microorganisms7080233 https://doaj.org/article/9bd487734a4b4c6187f02d830683dd35 Microorganisms, Vol 7, Iss 8, p 233 (2019) fish Salmo salar antibiotics florfenicol oxolinic acid intestinal bacteria microbiota high-throughput amplicon sequencing Biology (General) QH301-705.5 article 2019 ftdoajarticles https://doi.org/10.3390/microorganisms7080233 2022-12-30T22:19:44Z The intestinal microbiota of certain farmed fish are often exposed to antimicrobial substances, such as antibiotics, that are used to prevent and treat bacterial diseases. Antibiotics that kill or inhibit the growth of harmful microbes can rapidly alter intestinal microbial diversity and composition, with potential effects on the host health. In this study, we have elucidated the impact of two antibiotics, florfenicol and oxolinic acid, by employing a high-throughput 16S rRNA gene amplicon sequencing technique on the distal and mid intestinal microbial communities of Atlantic salmon ( Salmo salar ). For this, Atlantic salmon were offered diets with or without antibiotics. We then investigated the bacterial communities in the intestinal mucus of the fish. Our results showed that antibiotic exposure shifts the intestinal microbial profile differentially. In addition, the bacterial compositions of the control and antibiotic-fed groups were significantly different. Antibiotic feeding altered the composition and abundance of the dominant bacterial phyla, namely Proteobacteria, Actinobacteria, Firmicutes, Spirochaetes, Bacteroidetes, Tenericutes, and Thermotogae. The bacterial association network analysis also indicated the differential pattern of co-occurrence of bacteria in the three study groups. The results regarding the differences in the structure and association of the intestinal microbiota of Atlantic salmon after florfenicol and oxolinic acid feeding can be employed to attenuate the adverse effects of antibiotic feeding on fish. Article in Journal/Newspaper Atlantic salmon Salmo salar Directory of Open Access Journals: DOAJ Articles Microorganisms 7 8 233 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
fish Salmo salar antibiotics florfenicol oxolinic acid intestinal bacteria microbiota high-throughput amplicon sequencing Biology (General) QH301-705.5 |
spellingShingle |
fish Salmo salar antibiotics florfenicol oxolinic acid intestinal bacteria microbiota high-throughput amplicon sequencing Biology (General) QH301-705.5 Shruti Gupta Jorge Fernandes Viswanath Kiron Antibiotic-Induced Perturbations Are Manifested in the Dominant Intestinal Bacterial Phyla of Atlantic Salmon |
topic_facet |
fish Salmo salar antibiotics florfenicol oxolinic acid intestinal bacteria microbiota high-throughput amplicon sequencing Biology (General) QH301-705.5 |
description |
The intestinal microbiota of certain farmed fish are often exposed to antimicrobial substances, such as antibiotics, that are used to prevent and treat bacterial diseases. Antibiotics that kill or inhibit the growth of harmful microbes can rapidly alter intestinal microbial diversity and composition, with potential effects on the host health. In this study, we have elucidated the impact of two antibiotics, florfenicol and oxolinic acid, by employing a high-throughput 16S rRNA gene amplicon sequencing technique on the distal and mid intestinal microbial communities of Atlantic salmon ( Salmo salar ). For this, Atlantic salmon were offered diets with or without antibiotics. We then investigated the bacterial communities in the intestinal mucus of the fish. Our results showed that antibiotic exposure shifts the intestinal microbial profile differentially. In addition, the bacterial compositions of the control and antibiotic-fed groups were significantly different. Antibiotic feeding altered the composition and abundance of the dominant bacterial phyla, namely Proteobacteria, Actinobacteria, Firmicutes, Spirochaetes, Bacteroidetes, Tenericutes, and Thermotogae. The bacterial association network analysis also indicated the differential pattern of co-occurrence of bacteria in the three study groups. The results regarding the differences in the structure and association of the intestinal microbiota of Atlantic salmon after florfenicol and oxolinic acid feeding can be employed to attenuate the adverse effects of antibiotic feeding on fish. |
format |
Article in Journal/Newspaper |
author |
Shruti Gupta Jorge Fernandes Viswanath Kiron |
author_facet |
Shruti Gupta Jorge Fernandes Viswanath Kiron |
author_sort |
Shruti Gupta |
title |
Antibiotic-Induced Perturbations Are Manifested in the Dominant Intestinal Bacterial Phyla of Atlantic Salmon |
title_short |
Antibiotic-Induced Perturbations Are Manifested in the Dominant Intestinal Bacterial Phyla of Atlantic Salmon |
title_full |
Antibiotic-Induced Perturbations Are Manifested in the Dominant Intestinal Bacterial Phyla of Atlantic Salmon |
title_fullStr |
Antibiotic-Induced Perturbations Are Manifested in the Dominant Intestinal Bacterial Phyla of Atlantic Salmon |
title_full_unstemmed |
Antibiotic-Induced Perturbations Are Manifested in the Dominant Intestinal Bacterial Phyla of Atlantic Salmon |
title_sort |
antibiotic-induced perturbations are manifested in the dominant intestinal bacterial phyla of atlantic salmon |
publisher |
MDPI AG |
publishDate |
2019 |
url |
https://doi.org/10.3390/microorganisms7080233 https://doaj.org/article/9bd487734a4b4c6187f02d830683dd35 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
Microorganisms, Vol 7, Iss 8, p 233 (2019) |
op_relation |
https://www.mdpi.com/2076-2607/7/8/233 https://doaj.org/toc/2076-2607 2076-2607 doi:10.3390/microorganisms7080233 https://doaj.org/article/9bd487734a4b4c6187f02d830683dd35 |
op_doi |
https://doi.org/10.3390/microorganisms7080233 |
container_title |
Microorganisms |
container_volume |
7 |
container_issue |
8 |
container_start_page |
233 |
_version_ |
1766360727227990016 |