Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool.
A major task in human genetics is to understand the nature of the evolutionary processes that have shaped the gene pools of contemporary populations. Ancient DNA studies have great potential to shed light on the evolution of populations because they provide the opportunity to sample from the same po...
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2009
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Online Access: | https://doi.org/10.1371/journal.pgen.1000343 https://doaj.org/article/9b80bbe7c7db4a139d46de93f6e5aa6f |
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ftdoajarticles:oai:doaj.org/article:9b80bbe7c7db4a139d46de93f6e5aa6f 2023-05-15T16:49:44+02:00 Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool. Agnar Helgason Carles Lalueza-Fox Shyamali Ghosh Sigrún Sigurethardóttir Maria Lourdes Sampietro Elena Gigli Adam Baker Jaume Bertranpetit Lilja Arnadóttir Unnur Thornorsteinsdottir Kári Stefánsson 2009-01-01T00:00:00Z https://doi.org/10.1371/journal.pgen.1000343 https://doaj.org/article/9b80bbe7c7db4a139d46de93f6e5aa6f EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC2613751?pdf=render https://doaj.org/toc/1553-7390 https://doaj.org/toc/1553-7404 1553-7390 1553-7404 doi:10.1371/journal.pgen.1000343 https://doaj.org/article/9b80bbe7c7db4a139d46de93f6e5aa6f PLoS Genetics, Vol 5, Iss 1, p e1000343 (2009) Genetics QH426-470 article 2009 ftdoajarticles https://doi.org/10.1371/journal.pgen.1000343 2022-12-31T14:11:46Z A major task in human genetics is to understand the nature of the evolutionary processes that have shaped the gene pools of contemporary populations. Ancient DNA studies have great potential to shed light on the evolution of populations because they provide the opportunity to sample from the same population at different points in time. Here, we show that a sample of mitochondrial DNA (mtDNA) control region sequences from 68 early medieval Icelandic skeletal remains is more closely related to sequences from contemporary inhabitants of Scotland, Ireland, and Scandinavia than to those from the modern Icelandic population. Due to a faster rate of genetic drift in the Icelandic mtDNA pool during the last 1,100 years, the sequences carried by the first settlers were better preserved in their ancestral gene pools than among their descendants in Iceland. These results demonstrate the inferential power gained in ancient DNA studies through the application of population genetics analyses to relatively large samples. Article in Journal/Newspaper Iceland Directory of Open Access Journals: DOAJ Articles PLoS Genetics 5 1 e1000343 |
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Directory of Open Access Journals: DOAJ Articles |
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language |
English |
topic |
Genetics QH426-470 |
spellingShingle |
Genetics QH426-470 Agnar Helgason Carles Lalueza-Fox Shyamali Ghosh Sigrún Sigurethardóttir Maria Lourdes Sampietro Elena Gigli Adam Baker Jaume Bertranpetit Lilja Arnadóttir Unnur Thornorsteinsdottir Kári Stefánsson Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool. |
topic_facet |
Genetics QH426-470 |
description |
A major task in human genetics is to understand the nature of the evolutionary processes that have shaped the gene pools of contemporary populations. Ancient DNA studies have great potential to shed light on the evolution of populations because they provide the opportunity to sample from the same population at different points in time. Here, we show that a sample of mitochondrial DNA (mtDNA) control region sequences from 68 early medieval Icelandic skeletal remains is more closely related to sequences from contemporary inhabitants of Scotland, Ireland, and Scandinavia than to those from the modern Icelandic population. Due to a faster rate of genetic drift in the Icelandic mtDNA pool during the last 1,100 years, the sequences carried by the first settlers were better preserved in their ancestral gene pools than among their descendants in Iceland. These results demonstrate the inferential power gained in ancient DNA studies through the application of population genetics analyses to relatively large samples. |
format |
Article in Journal/Newspaper |
author |
Agnar Helgason Carles Lalueza-Fox Shyamali Ghosh Sigrún Sigurethardóttir Maria Lourdes Sampietro Elena Gigli Adam Baker Jaume Bertranpetit Lilja Arnadóttir Unnur Thornorsteinsdottir Kári Stefánsson |
author_facet |
Agnar Helgason Carles Lalueza-Fox Shyamali Ghosh Sigrún Sigurethardóttir Maria Lourdes Sampietro Elena Gigli Adam Baker Jaume Bertranpetit Lilja Arnadóttir Unnur Thornorsteinsdottir Kári Stefánsson |
author_sort |
Agnar Helgason |
title |
Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool. |
title_short |
Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool. |
title_full |
Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool. |
title_fullStr |
Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool. |
title_full_unstemmed |
Sequences from first settlers reveal rapid evolution in Icelandic mtDNA pool. |
title_sort |
sequences from first settlers reveal rapid evolution in icelandic mtdna pool. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2009 |
url |
https://doi.org/10.1371/journal.pgen.1000343 https://doaj.org/article/9b80bbe7c7db4a139d46de93f6e5aa6f |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
PLoS Genetics, Vol 5, Iss 1, p e1000343 (2009) |
op_relation |
http://europepmc.org/articles/PMC2613751?pdf=render https://doaj.org/toc/1553-7390 https://doaj.org/toc/1553-7404 1553-7390 1553-7404 doi:10.1371/journal.pgen.1000343 https://doaj.org/article/9b80bbe7c7db4a139d46de93f6e5aa6f |
op_doi |
https://doi.org/10.1371/journal.pgen.1000343 |
container_title |
PLoS Genetics |
container_volume |
5 |
container_issue |
1 |
container_start_page |
e1000343 |
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1766039934862360576 |