Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil
Introduction To determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) anti-Toxoplasma gondii antibodies among pregnant and postpartum women attended within the public healthcare system in Niterói, State of Rio de Janeiro, and to detect possible exposure factors associated wit...
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ftdoajarticles:oai:doaj.org/article:9b7e70e63cdd4d0eb02fec38f9cb4a93 2023-05-15T15:12:59+02:00 Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil Fernanda Loureiro de Moura Maria Regina Reis Amendoeira Otílio Machado Pereira Bastos Danuza Pinheiro Bastos Garcia de Mattos Ana Beatriz Monteiro Fonseca José Leonardo Nicolau Leandro Baptista das Neves Patricia Riddell Millar 2013-02-01T00:00:00Z https://doaj.org/article/9b7e70e63cdd4d0eb02fec38f9cb4a93 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000200200 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/9b7e70e63cdd4d0eb02fec38f9cb4a93 Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 2, Pp 200-207 (2013) Toxoplasma gondii Pregnant women Postpartum women Seroprevalence Arctic medicine. Tropical medicine RC955-962 article 2013 ftdoajarticles 2022-12-30T23:24:30Z Introduction To determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) anti-Toxoplasma gondii antibodies among pregnant and postpartum women attended within the public healthcare system in Niterói, State of Rio de Janeiro, and to detect possible exposure factors associated with T. gondii infection in this population. Methods IgM and IgG anti-T. gondii antibodies were investigated in 276 pregnant and 124 postpartum women by using the indirect immunofluorescence (IFAT) and immunoenzymatic assay (ELISA) techniques. The participants were selected by convenience sampling. All these 400 patients filled out a free and informed consent statement, answered an epidemiological questionnaire and were informed about the disease. Results Among the 400 samples analyzed, 234 (58.5%) were reactive to IgG anti-T. gondii antibodies, according to the IFAT and/or ELISA assay. One pregnant woman was found to be reactive to IgM anti-T. gondii antibodies, with an intermediate IgG avidity test. Risk factor analysis showed that seropositivity was significantly associated (p<0.05) with age, contact with cats and presence of rodents at home. Through a logistic regression model, these associations were confirmed for age and contact with cats, while education at least of the high school level was found to be a protective factor. Conclusions The prevalence rate of IgG anti-T. gondii antibodies in the City of Niterói was high and the risk factors for infection detected after multivariate analysis were: age over 30 years, contact with cats and education levels lower than university graduate level. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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Toxoplasma gondii Pregnant women Postpartum women Seroprevalence Arctic medicine. Tropical medicine RC955-962 |
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Toxoplasma gondii Pregnant women Postpartum women Seroprevalence Arctic medicine. Tropical medicine RC955-962 Fernanda Loureiro de Moura Maria Regina Reis Amendoeira Otílio Machado Pereira Bastos Danuza Pinheiro Bastos Garcia de Mattos Ana Beatriz Monteiro Fonseca José Leonardo Nicolau Leandro Baptista das Neves Patricia Riddell Millar Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
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Toxoplasma gondii Pregnant women Postpartum women Seroprevalence Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction To determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) anti-Toxoplasma gondii antibodies among pregnant and postpartum women attended within the public healthcare system in Niterói, State of Rio de Janeiro, and to detect possible exposure factors associated with T. gondii infection in this population. Methods IgM and IgG anti-T. gondii antibodies were investigated in 276 pregnant and 124 postpartum women by using the indirect immunofluorescence (IFAT) and immunoenzymatic assay (ELISA) techniques. The participants were selected by convenience sampling. All these 400 patients filled out a free and informed consent statement, answered an epidemiological questionnaire and were informed about the disease. Results Among the 400 samples analyzed, 234 (58.5%) were reactive to IgG anti-T. gondii antibodies, according to the IFAT and/or ELISA assay. One pregnant woman was found to be reactive to IgM anti-T. gondii antibodies, with an intermediate IgG avidity test. Risk factor analysis showed that seropositivity was significantly associated (p<0.05) with age, contact with cats and presence of rodents at home. Through a logistic regression model, these associations were confirmed for age and contact with cats, while education at least of the high school level was found to be a protective factor. Conclusions The prevalence rate of IgG anti-T. gondii antibodies in the City of Niterói was high and the risk factors for infection detected after multivariate analysis were: age over 30 years, contact with cats and education levels lower than university graduate level. |
format |
Article in Journal/Newspaper |
author |
Fernanda Loureiro de Moura Maria Regina Reis Amendoeira Otílio Machado Pereira Bastos Danuza Pinheiro Bastos Garcia de Mattos Ana Beatriz Monteiro Fonseca José Leonardo Nicolau Leandro Baptista das Neves Patricia Riddell Millar |
author_facet |
Fernanda Loureiro de Moura Maria Regina Reis Amendoeira Otílio Machado Pereira Bastos Danuza Pinheiro Bastos Garcia de Mattos Ana Beatriz Monteiro Fonseca José Leonardo Nicolau Leandro Baptista das Neves Patricia Riddell Millar |
author_sort |
Fernanda Loureiro de Moura |
title |
Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
title_short |
Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
title_full |
Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
title_fullStr |
Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
title_full_unstemmed |
Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil |
title_sort |
prevalence and risk factors for toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the city of niterói, state of rio de janeiro, brazil |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2013 |
url |
https://doaj.org/article/9b7e70e63cdd4d0eb02fec38f9cb4a93 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 46, Iss 2, Pp 200-207 (2013) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000200200 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/9b7e70e63cdd4d0eb02fec38f9cb4a93 |
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1766343589663604736 |